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Medications for Endometriosis

The medications listed below are related to or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
norethindrone 5.3 99 reviews for norethindrone to treat Endometriosis Rx X N X
Generic name:
norethindrone systemic
Brand name:
Gallifrey
Drug class:
contraceptives, progestins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Lupron Depot 5.4 122 reviews for Lupron Depot to treat Endometriosis Rx X N
Generic name:
leuprolide systemic
Drug class:
hormones/antineoplastics, gonadotropin releasing hormones
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Orilissa 5.4 125 reviews for Orilissa to treat Endometriosis Rx N
Generic name:
elagolix systemic
Drug class:
gonadotropin-releasing hormone antagonists
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
progesterone Off-label 5.0 3 reviews for progesterone to treat Endometriosis Rx/OTC B N
Generic name:
progesterone systemic
Drug class:
progestins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Natural Product Monographs, Prescribing Information
Off-label:
Yes
medroxyprogesterone 5.7 95 reviews for medroxyprogesterone to treat Endometriosis Rx X N
Generic name:
medroxyprogesterone systemic
Brand names:
Provera, depo-subQ provera 104
Drug class:
hormones/antineoplastics, contraceptives, progestins
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Zoladex 6.7 68 reviews for Zoladex to treat Endometriosis Rx X N
Generic name:
goserelin systemic
Drug class:
hormones/antineoplastics, gonadotropin releasing hormones
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Provera 6.8 5 reviews for Provera to treat Endometriosis Rx X N
Generic name:
medroxyprogesterone systemic
Drug class:
hormones/antineoplastics, contraceptives, progestins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
danazol 6.8 4 reviews for danazol to treat Endometriosis Rx X N
Generic name:
danazol systemic
Brand name:
Danocrine
Drug class:
antigonadotropic agents
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
desogestrel / ethinyl estradiol Off-label 8.8 4 reviews for desogestrel / ethinyl estradiol to treat Endometriosis Rx X N X
Generic name:
desogestrel / ethinyl estradiol systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
Sprintec 5.5 21 reviews for Sprintec to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / norgestimate systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
depo-subQ provera 104 7.6 16 reviews for depo-subQ provera 104 to treat Endometriosis Rx X N
Generic name:
medroxyprogesterone systemic
Drug class:
hormones/antineoplastics, contraceptives, progestins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
leuprolide 5.3 158 reviews for leuprolide to treat Endometriosis Rx X N
Generic name:
leuprolide systemic
Brand name:
Lupron Depot
Drug class:
hormones/antineoplastics, gonadotropin releasing hormones
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Lutera Off-label 7.0 6 reviews for Lutera to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / levonorgestrel systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
Aviane Off-label 7.1 9 reviews for Aviane to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / levonorgestrel systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
Seasonique Off-label 5.2 30 reviews for Seasonique to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / levonorgestrel systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
ethinyl estradiol / levonorgestrel Off-label 5.4 111 reviews for ethinyl estradiol / levonorgestrel to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / levonorgestrel systemic
Brand names:
Lutera, Aviane, Seasonique, Seasonale, Jolessa, LoSeasonique, Kurvelo, Levora, Sronyx, Amethia Lo, CamreseLo, Chateal, Enpresse, Falmina, Lessina, Myzilra, Orsythia, Portia, Trivora
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
ethinyl estradiol / norethindrone Off-label 6.2 77 reviews for ethinyl estradiol / norethindrone to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / norethindrone systemic
Drug class:
contraceptives, sex hormone combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
Myfembree 7.8 8 reviews for Myfembree to treat Endometriosis Rx N X
Generic name:
estradiol / norethindrone / relugolix systemic
Drug class:
sex hormone combinations
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Seasonale Off-label 5.0 3 reviews for Seasonale to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / levonorgestrel systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
Cryselle Off-label 5.8 9 reviews for Cryselle to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / norgestrel systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
Danocrine 10 1 review for Danocrine to treat Endometriosis Rx X N
Generic name:
danazol systemic
Drug class:
antigonadotropic agents
For consumers:
dosage, interactions, side effects
Gallifrey Rate Add review Rx X N X
Generic name:
norethindrone systemic
Drug class:
progestins
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
goserelin 6.7 69 reviews for goserelin to treat Endometriosis Rx X N
Generic name:
goserelin systemic
Brand name:
Zoladex
Drug class:
hormones/antineoplastics, gonadotropin releasing hormones
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Jolessa Off-label 8.3 3 reviews for Jolessa to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / levonorgestrel systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
elagolix 5.4 128 reviews for elagolix to treat Endometriosis Rx N
Generic name:
elagolix systemic
Brand name:
Orilissa
Drug class:
gonadotropin-releasing hormone antagonists
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
ethinyl estradiol / norgestimate 5.2 77 reviews for ethinyl estradiol / norgestimate to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / norgestimate systemic
Brand names:
Sprintec, Estarylla, Tri-Sprintec, Previfem, Mono-Linyah, Tri-Estarylla, Tri-Linyah, Tri-Lo-Marzia, Tri-Lo-Sprintec, Tri-Previfem
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Low-Ogestrel-28 Off-label 8.0 2 reviews for Low-Ogestrel-28 to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / norgestrel systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
Estarylla 3.7 7 reviews for Estarylla to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / norgestimate systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
LoSeasonique Off-label 6.6 10 reviews for LoSeasonique to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / levonorgestrel systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
Synarel 7.2 9 reviews for Synarel to treat Endometriosis Rx X N
Generic name:
nafarelin systemic
Drug class:
gonadotropin releasing hormones
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Tri-Sprintec 5.0 13 reviews for Tri-Sprintec to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / norgestimate systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
ethinyl estradiol / ethynodiol Off-label 9.0 1 review for ethinyl estradiol / ethynodiol to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / ethynodiol systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
etonogestrel Off-label 4.5 11 reviews for etonogestrel to treat Endometriosis Rx X N
Generic name:
etonogestrel systemic
Drug class:
contraceptives, progestins
For consumers:
dosage, interactions, side effects
Off-label:
Yes
Kurvelo Off-label 10 1 review for Kurvelo to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / levonorgestrel systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
Levora Off-label 5.3 7 reviews for Levora to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / levonorgestrel systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
nafarelin 7.2 9 reviews for nafarelin to treat Endometriosis Rx X N
Generic name:
nafarelin systemic
Brand name:
Synarel
Drug class:
gonadotropin releasing hormones
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph
Previfem 9.0 1 review for Previfem to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / norgestimate systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Sronyx Off-label Rate Add review Rx X N X
Generic name:
ethinyl estradiol / levonorgestrel systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
Amethia Lo Off-label Rate Add review Rx X N X
Generic name:
ethinyl estradiol / levonorgestrel systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
CamreseLo Off-label Rate Add review Rx X N X
Generic name:
ethinyl estradiol / levonorgestrel systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
Chateal Off-label 4.0 4 reviews for Chateal to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / levonorgestrel systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
Elinest Off-label Rate Add review Rx X N X
Generic name:
ethinyl estradiol / norgestrel systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
Enpresse Off-label Rate Add review Rx X N X
Generic name:
ethinyl estradiol / levonorgestrel systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
ethinyl estradiol / norgestrel Off-label 6.2 11 reviews for ethinyl estradiol / norgestrel to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / norgestrel systemic
Brand names:
Cryselle, Low-Ogestrel-28, Elinest
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
Falmina Off-label 5.5 2 reviews for Falmina to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / levonorgestrel systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
Lessina Off-label 3.3 3 reviews for Lessina to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / levonorgestrel systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
leuprolide / norethindrone Rate Add review Rx X N X
Generic name:
leuprolide / norethindrone systemic
Brand name:
Lupaneta Pack
Drug class:
sex hormone combinations
For consumers:
dosage, interactions, side effects
Lupaneta Pack Rate Add review Rx X N X
Generic name:
leuprolide / norethindrone systemic
Drug class:
sex hormone combinations
For consumers:
dosage, interactions, side effects
Mono-Linyah 2.0 4 reviews for Mono-Linyah to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / norgestimate systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Myzilra Off-label Rate Add review Rx X N X
Generic name:
ethinyl estradiol / levonorgestrel systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
Orsythia Off-label 1.0 1 review for Orsythia to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / levonorgestrel systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
Portia Off-label 5.0 2 reviews for Portia to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / levonorgestrel systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
Tri-Estarylla Rate Add review Rx X N X
Generic name:
ethinyl estradiol / norgestimate systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Tri-Linyah 8.0 2 reviews for Tri-Linyah to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / norgestimate systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Tri-Lo-Marzia 4.8 4 reviews for Tri-Lo-Marzia to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / norgestimate systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Tri-Lo-Sprintec 6.7 3 reviews for Tri-Lo-Sprintec to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / norgestimate systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Tri-Previfem 5.7 3 reviews for Tri-Previfem to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / norgestimate systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Trivora Off-label 8.0 1 review for Trivora to treat Endometriosis Rx X N X
Generic name:
ethinyl estradiol / levonorgestrel systemic
Drug class:
contraceptives
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Off-label:
Yes
estradiol / norethindrone / relugolix 7.8 8 reviews for estradiol / norethindrone / relugolix to treat Endometriosis Rx N X
Generic name:
estradiol / norethindrone / relugolix systemic
Brand name:
Myfembree
Drug class:
sex hormone combinations
For consumers:
dosage, interactions, side effects

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Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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