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Medications for Endometriosis

About Endometriosis:  Endometriosis is a condition in which the tissue that normally lines the uterus (endometrium) grows in other areas of the body, causing pain, irregular bleeding, and frequently infertility.

The tissue growth typically occurs in the pelvic area, outside of the uterus, on the ovaries, bowel, rectum, bladder, and the delicate lining of the pelvis, but it can occur in other areas of the body as well.

Drugs Used to Treat Endometriosis

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
Depo-Provera X N 54 reviews
6.0

Generic name: medroxyprogesterone systemic

Drug class: hormones/antineoplastics, contraceptives, progestins

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

norethindrone X N X 33 reviews
5.0

Generic name: norethindrone systemic

Brand names:  Aygestin, Camila, Jolivette, Errin, Nora-Be, Heather, Ortho Micronor, Nor-QD, Sharobel, Deblitane, Incassia, Jencycla, Lyza, Norlyda, Norlyroc …show all

Drug class: contraceptives, progestins

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Lupron Depot X N 89 reviews
5.0

Generic name: leuprolide systemic

Drug class: hormones/antineoplastics, gonadotropin releasing hormones

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

medroxyprogesterone X N 61 reviews
5.0

Generic name: medroxyprogesterone systemic

Brand names:  Depo-Provera, Provera, Depo-Provera Contraceptive, depo-subQ provera 104 …show all

Drug class: hormones/antineoplastics, contraceptives, progestins

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Zoladex X N 26 reviews
6.0

Generic name: goserelin systemic

Drug class: hormones/antineoplastics, gonadotropin releasing hormones

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Lutera Off Label X N X 5 reviews
8.0

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

Aviane Off Label X N X 7 reviews
8.0

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

Provera X N 2 reviews
4.0

Generic name: medroxyprogesterone systemic

Drug class: hormones/antineoplastics, contraceptives, progestins

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Aygestin X N X 2 reviews
7.0

Generic name: norethindrone systemic

Drug class: contraceptives, progestins

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

ethinyl estradiol / levonorgestrel Off Label X N X 85 reviews
5.0

Generic name: ethinyl estradiol / levonorgestrel systemic

Brand names:  Lutera, Aviane, Seasonique, Seasonale, Jolessa, Levlen, Levora, LoSeasonique, Quasense, Orsythia, Triphasil, Amethia Lo, CamreseLo, Chateal, Enpresse, Falmina, Kurvelo, Lessina, Myzilra, Portia, Sronyx, Trivora …show all

Drug class: contraceptives

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, Prescribing Information

Off Label: Yes

Seasonique Off Label X N X 29 reviews
5.0

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

progesterone Off Label B N 1 review
7.0

Generic name: progesterone systemic

Drug class: progestins

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Natural Product Monographs, Prescribing Information

Off Label: Yes

Sprintec X N X 14 reviews
6.0

Generic name: ethinyl estradiol / norgestimate systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

leuprolide X N 123 reviews
5.0

Generic name: leuprolide systemic

Brand name:  Lupron Depot

Drug class: hormones/antineoplastics, gonadotropin releasing hormones

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Depo-Provera Contraceptive X N Add review Rate

Generic name: medroxyprogesterone systemic

Drug class: hormones/antineoplastics, contraceptives, progestins

For consumers: dosage, interactions, side effects

danazol X N 3 reviews
7.0

Generic name: danazol systemic

Brand name:  Danocrine

Drug class: antigonadotropic agents

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Ortho Tri-Cyclen X N X 1 review
2.0

Generic name: ethinyl estradiol / norgestimate systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Seasonale Off Label X N X 2 reviews
7.0

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

ethinyl estradiol / norethindrone X N X 70 reviews
6.0

Generic name: ethinyl estradiol / norethindrone systemic

Drug class: contraceptives, sex hormone combinations

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, Prescribing Information

Mononessa X N X 5 reviews
7.0

Generic name: ethinyl estradiol / norgestimate systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

ethinyl estradiol / norgestimate X N X 48 reviews
6.0

Generic name: ethinyl estradiol / norgestimate systemic

Brand names:  Sprintec, Ortho Tri-Cyclen, Mononessa, TriNessa, Tri-Sprintec, Ortho Tri-Cyclen Lo, Ortho Cyclen, Estarylla, Mono-Linyah, Previfem, Tri-Estarylla, Tri-Linyah, Tri-Lo-Marzia, Tri-Lo-Sprintec, Tri-Previfem, TriNessa Lo …show all

Drug class: contraceptives

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, Prescribing Information

Jolessa Off Label X N X 3 reviews
8.0

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

Cryselle Off Label X N X 8 reviews
5.0

Generic name: ethinyl estradiol / norgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

TriNessa X N X Add review
8.0

Generic name: ethinyl estradiol / norgestimate systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

desogestrel / ethinyl estradiol Off Label X N X 3 reviews
8.0

Generic name: desogestrel / ethinyl estradiol systemic

Drug class: contraceptives

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, Prescribing Information

Off Label: Yes

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Topics under Endometriosis

Learn more about Endometriosis

Micromedex® Care Notes

Symptoms and treatments

Mayo Clinic Reference

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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