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Medications for Endometriosis

What is Endometriosis:  Endometriosis is a condition in which the tissue that normally lines the uterus (endometrium) grows in other areas of the body, causing pain, irregular bleeding, and frequently infertility.

The tissue growth typically occurs in the pelvic area, outside of the uterus, on the ovaries, bowel, rectum, bladder, and the delicate lining of the pelvis, but it can occur in other areas of the body as well.

Medications to treat Endometriosis

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
Depo-Provera Rx X N 47 reviews
6.0

Generic name: medroxyprogesterone systemic

Drug class: hormones/antineoplastics, contraceptives, progestins

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Lupron Rx X N 21 reviews
5.0

Generic name: leuprolide systemic

Drug class: hormones/antineoplastics, gonadotropin releasing hormones

For consumers: dosage, interactions, side effects

 
norethindrone Rx X N X 27 reviews
5.0

Generic name: norethindrone systemic

Brand names:  Aygestin, Camila, Jolivette, Nora-Be, Errin, Ortho Micronor, Nor-QD, Deblitane, Incassia, Jencycla, Lyza, Norlyda, Norlyroc, Sharobel

Drug class: contraceptives, progestins

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Lupron Depot Rx X N 77 reviews
6.0

Generic name: leuprolide systemic

Drug class: hormones/antineoplastics, gonadotropin releasing hormones

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Zoladex Rx X N 21 reviews
6.0

Generic name: goserelin systemic

Drug class: hormones/antineoplastics, gonadotropin releasing hormones

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Aviane Off Label Rx X N X 7 reviews
8.0

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
Aygestin Rx X N X 2 reviews
7.0

Generic name: norethindrone systemic

Drug class: contraceptives, progestins

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Lutera Off Label Rx X N X 4 reviews
7.0

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
medroxyprogesterone Rx X N 53 reviews
6.0

Generic name: medroxyprogesterone systemic

Brand names:  Depo-Provera, Provera, Depo-Provera Contraceptive, depo-subQ provera 104

Drug class: hormones/antineoplastics, contraceptives, progestins

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Seasonique Off Label Rx X N X 28 reviews
5.0

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
Provera Rx X N 2 reviews
4.0

Generic name: medroxyprogesterone systemic

Drug class: hormones/antineoplastics, contraceptives, progestins

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Loestrin 24 Fe Rx X N X 20 reviews
6.0

Generic name: ethinyl estradiol / norethindrone systemic

Drug class: contraceptives, sex hormone combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
progesterone Off Label Rx/OTC B N 1 review
7.0

Generic name: progesterone systemic

Drug class: progestins

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Natural Product Monographs, Prescribing Information

Off Label: Yes

 
Lupron Depot 3.75 mg Rx X N 6 reviews
5.0

Generic name: leuprolide systemic

Drug class: hormones/antineoplastics, gonadotropin releasing hormones

For consumers: dosage, interactions, side effects

 
Sprintec Rx X N X 13 reviews
6.0

Generic name: ethinyl estradiol / norgestimate systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Depo-Provera Contraceptive Rx X N Add review Add

Generic name: medroxyprogesterone systemic

Drug class: hormones/antineoplastics, contraceptives, progestins

For consumers: dosage, interactions, side effects

 
Lupron Depot 11.25 mg Rx X N 2 reviews
3.0

Generic name: leuprolide systemic

Drug class: hormones/antineoplastics, gonadotropin releasing hormones

For consumers: dosage, interactions, side effects

 
Microgestin Fe 1 / 20 Rx X N X 11 reviews
7.0

Generic name: ethinyl estradiol / norethindrone systemic

Drug class: contraceptives, sex hormone combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Seasonale Off Label Rx X N X 2 reviews
7.0

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
Ortho Tri-Cyclen Rx X N X Add review Add

Generic name: ethinyl estradiol / norgestimate systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Cryselle Off Label Rx X N X 7 reviews
6.0

Generic name: ethinyl estradiol / norgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
ethinyl estradiol / levonorgestrel Off Label Rx X N X 77 reviews
6.0

Generic name: ethinyl estradiol / levonorgestrel systemic

Brand names:  Aviane, Lutera, Seasonique, Seasonale, Jolessa, Levlen, Levora, Quasense, LoSeasonique, Orsythia, CamreseLo, Falmina, Portia, Sronyx, Triphasil, Enpresse, Kurvelo, Nordette, Amethia Lo, Chateal, Lessina, Levlite, Myzilra, Preven EC, Triphasil-28, Trivora, Trivora-28

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

Off Label: Yes

 
Mononessa Rx X N X 4 reviews
7.0

Generic name: ethinyl estradiol / norgestimate systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
danazol Rx X N 3 reviews
7.0

Generic name: danazol systemic

Brand name:  Danocrine

Drug class: antigonadotropic agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Jolessa Off Label Rx X N X 3 reviews
8.0

Generic name: ethinyl estradiol / levonorgestrel systemic

Drug class: contraceptives

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
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Topics under Endometriosis

Learn more about Endometriosis

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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