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Provera (medroxyprogesterone) Drug Interactions

A total of 255 drugs are known to interact with Provera (medroxyprogesterone).

  • 17 major drug interactions
  • 229 moderate drug interactions
  • 9 minor drug interactions

Show all medications in the database that may interact with Provera (medroxyprogesterone).

Check for interactions

Type in a drug name to check for interactions with Provera (medroxyprogesterone).

Most frequently checked interactions

View interaction reports for Provera (medroxyprogesterone) and the medicines listed below.

  • Advil (ibuprofen)
  • Aleve (naproxen)
  • Ambien (zolpidem)
  • Ativan (lorazepam)
  • Clomid (clomiphene)
  • Cymbalta (duloxetine)
  • estradiol (Estrace, Estradiol Patch, Climara, Vivelle-Dot, Minivelle, Estrogel, Vivelle, Estrogen Patches, Femring, Divigel, Delestrogen, Estrofem, Estraderm, Evamist, Alora, Elestrin, Progynova, Estradot, Elleste Solo, Depo-Estradiol, Valergen, Primogyn Depot, Oestradiol Implants, Oesclim, Estradot 37.5, Oestrogel Pump-Pack, Dermestril, Evorel, Aerodiol, Sandrena, Fematrix, Nuvelle TS Phase I, FemTab, Estrasorb, Femtran, Climodien, Organon Oestradiol, Estradiol G GAM, Provames, Thaissept, Estra Pellets, Depogen, Dep Gynogen, Gynogen LA 20, Dioval 40, Dioval XX, Duragen, Estra-C, Estra-V 40, Estro-Cyp, Gynodiol, Estro-Span 40, Medidiol 10, Dura-Estrin, Fempatch, Esclim, Estragyn LA 5, Clinagen LA 40, Estro-LA, Menaval-20, Estradot 50, Estradot 75, Estradot 100, FemSeven, Progynova TS, Zumenon, Adgyn Estro, FemSeven Sequi Phase I, Menorest Patch, Climaval, Bedol, Delidose, Dermestril Septem, Estrapatch, Estreva, Femsept, Menorest, Oestrodose, Oestrogel, Oromone, Systen, Thais, Dotti, Menostar, Femtrace)
  • Excedrin (acetaminophen / aspirin / caffeine)
  • Flexeril (cyclobenzaprine)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • hydrochlorothiazide (HydroDIURIL, Microzide, Esidrix, Oretic, Aquazide H, Diaqua, Hydro Par, Ezide, Carozide, Loqua)
  • ibuprofen (Advil, Motrin, IBU, Advil Liqui-Gels, Motrin IB, Proprinal, Advil Children's, Caldolor, Children's Motrin, Childrens Ibuprofen Berry, Motrin Childrens, Rufen, Ibuprofen PMR, Ibu-8, Motrin Pediatric, Menadol, Nuprin, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, Advil Migraine, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, NeoProfen, Ibu-Tab, Genpril, Haltran, IBU-200, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Actiprofen, Addaprin, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, Motrin Junior Strength, Motrin Infant Drops, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
  • levothyroxine (Synthroid, Levoxyl, Tirosint, Levothroid, Eltroxin, Levothyrox, Euthyrox, Unithroid, L Thyroxine Roche, Levo-T, Oroxine, Eutroxsig, Novothyrox, Tirosint-Sol, Levotabs, Levotec, Evotrox)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • metformin (Glucophage, Glumetza, Glucophage XR, Fortamet, Riomet)
  • Mirena (levonorgestrel)
  • Nexium (esomeprazole)
  • Nexplanon (etonogestrel)
  • Norco (acetaminophen / hydrocodone)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • Premarin (conjugated estrogens)
  • simvastatin (Zocor, FloLipid)
  • Synthroid (levothyroxine)
  • tranexamic acid (Lysteda, Cyklokapron)
  • trazodone (Desyrel, Oleptro, Desyrel Dividose)
  • Tylenol (acetaminophen)
  • Vitamin D3 (cholecalciferol)
  • Zoloft (sertraline)

Provera (medroxyprogesterone) alcohol/food interactions

There are 3 alcohol/food interactions with Provera (medroxyprogesterone)

Provera (medroxyprogesterone) disease interactions

There are 13 disease interactions with Provera (medroxyprogesterone) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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