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User Reviews for Depo-Provera

Depo-Provera has an average rating of 4.3 out of 10 from a total of 1,861 ratings on Drugs.com. 29% of reviewers reported a positive effect, while 55% reported a negative effect.

Condition Avg. Rating Reviews Compare
Birth Control  
5.2
966 reviews 340 medications
Abnormal Uterine Bleeding  
2.8
801 reviews 102 medications
Endometriosis  
5.8
79 reviews 102 medications
Amenorrhea  
7.3
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Endometrial Cancer  
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Endometrial Hyperplasia, Prophylaxis  
9.0
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Summary of Depo-Provera reviews 4.3 1,861 reviews

Reviews may be edited to correct grammar/spelling, or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Depo-Provera

AB · Taken for 10 years or more September 5, 2020

For Abnormal Uterine Bleeding: “I have been on Depo for 10 years without missing a injection. I had no side effects and LOVED not having a period. Something in the drug has obviously been altered because I'm having a period now, and nothing else in my routine has changed. This began around February/March of this year (2020). I've still continued to get the injection, but am questioning what exactly has happened to the drug and why patients have not been informed about any changes to the drug.”

6 / 10
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Taza · Taken for 1 to 6 months July 3, 2021

For Abnormal Uterine Bleeding: “I’ve started the depo provera injection fairly recently 24 May 2021. I was on my period which I normally have for seven days but with this injection my period went from normal flow to a dark brown, slow flow which couldn’t fill a pad. To changing halfway in June to a medium heavy flow. I called the doctors in the early stages because when I read the symptoms it said spotting but not heavy flow period. When I spoke to her it was like speaking to someone who doesn’t want to hear you. Not helpful at all. It’s now July I’ve been bleeding for a total of 42 days and counting. Will I get the 2nd injection in August? Nope. Would I recommend it? Nope. It really mucks up your emotions It has made me cry over stupid things. I had this injection so I could have sex without fear of pregnancy have I been able to have sex no. My advice once again it’s not the one to get”

1 / 10
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GG February 15, 2021

For Abnormal Uterine Bleeding: “I have been on Depo Provera for 22 years. After my very first injection 22 years ago, I have had zero periods and zero breakthrough bleeding. Zero side effects. Nothing. This has been a blessing. I had my last Depo Shot on 1/12/21. My next one is not due until 3/30/21. Today I wake up and have bleeding. While I realize that this can be due to other causes, I was just reading that there are others experiencing this. Perhaps there is something wrong with a batch of the medication? Will see what happens from here and keep an eye on it.”

10 / 10
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Christina d. · Taken for 1 to 6 months June 9, 2020

For Abnormal Uterine Bleeding: “I can't believe all the reviews I'm reading about the shot making you bleed for weeks or even months because now its happening to me. I got the shot for the first time in late April and I started to bleed about 2 and a half weeks ago. And I'm still bleeding. This really sucks. Being on a period everyday is not what I signed up for. I will NOT be getting it again and I just want my period to go back to normal. Would NOT recommend getting this to anyone!”

1 / 10
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Ms.Queen · Taken for 1 to 6 months September 18, 2020

For Abnormal Uterine Bleeding: “I feel better knowing I'm not going through this horrible experience of Depo-provera alone. I loved the depo just because I didn't have periods over 5 years using this shot. And now to bleed every day longer than 10 days is very depressing. I would like to know what I can do to make this bleeding stop. This can't be healthy”

1 / 10
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GG January 4, 2021

For Abnormal Uterine Bleeding: “I've been on Depo-Provera for over a decade with no side effects, no periods or breakthrough bleeding. I have never missed an injection, however 3 weeks before my next injection I'm bleeding. This is an unwelcome, painful surprise because I've been without a period for as long as I've been on this birth control which has been almost 14 years. Something has changed with the medication”

8 / 10
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Amanda · Taken for 1 to 6 months February 28, 2020

For Abnormal Uterine Bleeding: “I got on the shot in early Nov 2019, it's now Feb 27th and I have been on a period since. Not a light period but a heavy "blood clot" type one. I'll never get this shot again, and I will not recommend it to anyone.”

1 / 10
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Frequently asked questions

Bananamom · Taken for less than 1 month October 4, 2020

For Abnormal Uterine Bleeding: “I took Depo-Provera injection many years ago. I never had a period or spotting from the first shot. I was on it for 6 years no issues other than weight gain. I got the shot again on September 10, 2020. I started bleeding 10 days ago. The cramps are extreme to the point I don't want to get out of bed. Which is not possible, I have 3 children age 8, 2, and 1 and a stay at home mom. Over the counter medication does not help with pain. There are too many of us experiencing the same things and a lot of us have already taken depo before with no issues.”

1 / 10
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Kat · Taken for 1 to 6 months February 10, 2020

For Abnormal Uterine Bleeding: “Worst contraceptive ever. I had my first depo shot on the 9th of Jan. Approximately two weeks after I started spotting and then bleeding heavily. I am so mad that my doctor never indicated or told me about any of these side effects. I will not be going back for a second injection. Now, I feel like I am on a permanent menstrual cycle. If any of you ladies are really wanting to do something about this horrible drug, report it to the FDA. And also to Pfizer on their website. I believe this drug needs to be removed from the market. I don't think any woman wants to keep bleeding for months on end at a time.”

1 / 10
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emma · Taken for 1 to 2 years February 13, 2020

For Abnormal Uterine Bleeding: “So I've been on this Depo-Provera shot since I was 16. I’m 18 now. I haven’t bleed on my period for 2 years. This past week I started to spot. Now I'm getting really heavy bleeding that’s bright red. It’s just a little odd that I’ve been on it for 2 years and haven’t bled at all and now all of the sudden I am. I am not sure if this is normal or not.”

5 / 10
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Harley21 July 13, 2021

For Abnormal Uterine Bleeding: “I have been taking the Depo-Provera for over 20 years, never had a period until a little over a year ago and now it comes and go's whenever it feels like, I never know when to expect it, i just thought this was normal due to the fact I had been on it so long, but then I went for my last injection a few days ago and I brought this up with my doctor and he told me this was not normal and is quite concerned and is now sending me to have a bunch of tests and freaking me out wondering what could be wrong and now I am reading all these reviews and thinking myself they have changed the product as everyone seems to be having similar issues, time to change to something different I think!”

1 / 10
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Keke · Taken for 10 years or more May 22, 2020

For Abnormal Uterine Bleeding: “I been on depo-provera for 20 years and was very happy but then when I love to out of state last year I start bleeding. I been bleeding for over 2 years now and I am so depress over this annoyance and my hubby is to. I really want sex but with the blood clots and non-stop bleeding I feel like I'm going crazy. I have tired everything the doctor has giving me bit it just won't stop and I'm sick of it. I'm mad and wish this bleeding just go away so I can try and be happy and work on my depression. Somebody please help me to stop this bleeding 2 years is too much.”

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Cry Baby · Taken for 1 to 6 months June 17, 2020

For Abnormal Uterine Bleeding: “Well I now know why this is a method of birth control....CUZ u won’t stop bleeding enough to be able to have sex!!!! Day 32 bleeding and counting.”

1 / 10
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JNK · Taken for less than 1 month August 20, 2020

For Abnormal Uterine Bleeding: “I was on depo from 2008-2011 with zero side effects. My periods were gone completely after the first shot and I had no weight gain and minimal mood swings. Fast forward to July 2020, all finished having children I got the shot again. I’ve now been bleeding heavily everyday for three weeks straight. Looking at this review forum makes me think the manufacturer made a change in early 2019 that quite obviously is not working with the majority of women’s menstruation. Who wants to bleed every day for a year?! NO ONE. I WILL NEVER GET THIS SHOT EVER AGAIN. NEVER.”

1 / 10
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Gladys · Taken for 6 months to 1 year June 1, 2020

For Birth Control: “I only see the negative sides effects of depo-provera being listed. Well I started the depo mid last year (2019) and so far so good I haven't hard any challenges or side effects while on it. Before the injection I used to bleed heavily with painful cramps but since I started this, no cramps with lighter bleeding that lasts for up to 3 days. Mind you before I used to bleed for seven days. I think it's all about ones body just because it failed on you doesn't mean it will fail on another person, people are different”

9 / 10
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Summer2012 · Taken for 1 to 6 months June 6, 2020

For Abnormal Uterine Bleeding: “I got the Depo-Provera in January - the only one I had. My heavy bleeding started the very next day and now 5 and a half months down the line I am still bleeding a heavy period everyday!! Doctors can not work out why or what is going on !!”

1 / 10
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Anonymous · Taken for 10 years or more March 4, 2021

For Abnormal Uterine Bleeding: “I have been on depo for TWENTY years and today have a full blown period. I mean, horrible cramping and all. I have never once had breakthrough bleeding or even a drop in 20 years. I received my injection on Jan 4th.”

10 / 10
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Vick · Taken for 1 to 6 months August 25, 2020

For Abnormal Uterine Bleeding: “I’ve took depo awhile back when I was around 17/18 , I’ve never experienced bleeding like this I recently got the Depo-Provera injection again because I have really horrible periods and extreme cramps, so I decided that I would go back on depo it was the worst thing I ever did. I experienced light spotting when I receive my first injection but I went in for my second around July 2020 and I’m still bleeding non stop and it’s getting very overwhelming because I can’t have sex with my boyfriend or if I do I have to take a shower first it’s really annoying I don’t recommend it to anyone you’ll be depressed for months”

1 / 10
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Hater of Depo · Taken for less than 1 month February 16, 2020

For Abnormal Uterine Bleeding: “I thought I would get Depo after a pregnancy scare my first jab was given at the beginning of August 2019, I bled from the next day onwards right up to when the next one was due so I decided not to have it, and it’s now mid-feb and I am still bleeding, I have had the occasional day where I think it’s over and it comes right back. In total over 6 months I have had 5 days of non-bleeding! It is almost like a form of torture, I thought it would be out my system by now!! DO NOT HAVE THIS, IT WILL BE THE BIGGEST REGRET OF YOUR LIFE!!”

1 / 10
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Zobow93 · Taken for 2 to 5 years March 27, 2021

For Abnormal Uterine Bleeding: “I’ve been on the Depo injection for 3+ years and have never had any bleeding. Until my last injection on 23rd Feb 2021 - I have been brown spotting for 1 week, and have woken up this morning with full blown red blood. I was so scared and I’m so glad I found this forum which shows it’s been happening to a lot of other women recently.”

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Anonymous May 31, 2020

For Abnormal Uterine Bleeding: “On Depo-provera I have been bleeding 4 weeks straight non stop!! I'm so crampy and wasn't bleeding up until I had the shot!! I had my son 10 weeks ago so decided to try this and what a REGRET!!!! Is there a bad batch or something?! As I had the shot a few years back and never had this problem”

1 / 10
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Adonnelly101 February 21, 2020

For Abnormal Uterine Bleeding: “I got this shot back in July. I went to the clinic for depo provera and I really thought this was gonna help. I guess I was wrong. Ever since August, I have had irregular bleeding but not a period just spotting and bleeding that happens at random times and I always get blood on my underwear and I don’t want to wear pads every single day. It’s been 7 months now and I’m still having this problem. I know it’s normal to have irregular bleeding but it should have stopped by now. This shot has been no help and I’m always having cramps and bleeding and I’m miserable. And if I stop the shot I’ll bleed for even longer and I really don’t want that. I don’t know what to do to make my periods regular and make my long periods never happen again. I don’t know if I should switch to the IUD cause I’ll probably have more side effects and I’m sick of it. Never should have gotten this shot. Big regret.”

2 / 10
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Anonymous · Taken for 6 months to 1 year June 10, 2020

For Abnormal Uterine Bleeding: “I got my first Depo-provera shot third week of October 2019. It is now June, I've had 4 shots and I’ve bled almost everyday. Sex is painful because progesterone makes me dry and I’m bleeding all the time. Almost 9 months straight of bleeding. I want to stop but I’m trying to wait for the 12 month mark where they said bleeding stops. We will see.”

1 / 10
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TIREDofBEINGprego · Taken for 6 months to 1 year June 1, 2020

For Abnormal Uterine Bleeding: “I started the depo at my 6 weeks check up after my 4th child. I get it every 3 months and have received in total 3 shots so far. I have been bleeding with a light period ever since the day I first got it. It's not as heavy as my usual period but it's enough to have to always wear a pad..”

4 / 10
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ARS · Taken for 1 to 6 months August 18, 2021

For Birth Control: “The depo is the worst thing I have ever put in my body. Ladies please re-consider before using this. Along with so many physical symptoms (nausea, acne, fatigue, heart burn, bloating cramps, bleeding constantly) the emotional symptoms are very prominent and worse than the physical ones. I believe this drug is destroying my relationship, I have no interest in sex or physical touch, I’m irritable all the time, depressed and have a constant feeling of emptiness that was not there before the depo my personality and mood took a full 180 on the depo. I am not going back in for my next injection. Something to also note is that the FDA is trying to pull this drug off the shelves. Please if you’re considering the depo do your research! I wish that I did.”

1 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.