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Gonadotropin-releasing hormone antagonists

What are Gonadotropin-releasing hormone antagonists

*Gonadotropin-releasing hormone (GnRH) antagonists are synthetic analogs of gonadotropin-releasing hormone, which is produced by the hypothalamus and controls the secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH) by the anterior pituitary. Gonadotropin-releasing hormone antagonists bind to gonadotropin-releasing hormone receptors and decrease the effect of gonadotropin-releasing hormone.

In men, gonadotropin-releasing hormone antagonists inhibit the release of luteinizing hormone, and consequently less testosterone is produced. Testosterone stimulates the growth of many forms of prostate cancer. Gonadotropin-releasing hormone antagonists are used to treat prostate cancer as by reducing the levels of testosterone the size of prostate cancer is reduced.

Gonadotropin-releasing hormone antagonists are used to treat women undergoing fertility treatment. It prevents early release of luteinizing hormone (LH) and premature ovulation in women being administered follicle-stimulating hormone (FSH) when preparing for in-vitro fertilization.

List of Gonadotropin-releasing hormone antagonists:

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Drug NameView by: Brand | Generic Reviews Avg. Ratings
Firmagon (Pro, More...)
generic name: degarelix
5 reviews
Antagon (More...)
generic name: ganirelix
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Cetrotide (Pro, More...)
generic name: cetrorelix
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Plenaxis (More...)
generic name: abarelix
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See Also

Medical conditions associated with gonadotropin-releasing hormone antagonists: