Gonadotropin releasing hormone (GnRH) is a hormone produced in the hypothalamus and transported to the pituitary gland through the blood stream. GnRH controls the secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. Secretion of GnRH is controlled by neural input from other parts of the brain and in females particularly, through negative feedback by the sex steroids.
More potent analogues of GnRH (compared to endogenous GnRH) have been synthesized and are used to treat endometriosis, fibroids, infertility and prostate cancer.
Subscribe to receive email notifications whenever new articles are published.
Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include Micromedex® (updated May 1st, 2017), Cerner Multum™ (updated May 3rd, 2017), Wolters Kluwer™ (updated May 2nd, 2017) and others. To view content sources and attributions, please refer to our editorial policy.