Leuprolide / Norethindrone Dosage
Medically reviewed by Drugs.com. Last updated on Jan 10, 2019.
Applies to the following strengths: 3.75 mg-5 mg; 11.25 mg-5 mg
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Endometriosis
Leuprolide: 3.75 mg IM once a month or 11.25 mg IM once every three months
Norethindrone: 5 mg once daily
Duration of therapy: Not to exceed six months
Comments: Leuprolide should be administered by a healthcare provider. If symptoms recur consider retreatment for up to another six months. Treatment beyond two six-month courses has not been studied and is not recommended. Due to different release characteristics, similar doses of leuprolide 1 month and 3 month depot formulations are not equivalent.
Renal Dose Adjustments
Leuprolide: Data not available
Norethindrone: Data not available
Liver Dose Adjustments
Leuprolide: Data not available
Norethindrone: Mild to moderate liver dysfunction: Data not available.
Norethindrone: Contraindicated in markedly impaired liver function or disease.
Precautions
Consult WARNINGS section for dosing related precautions.
Dialysis
Data not available
Other Comments
Reconstitution/preparation techniques: The manufacturer's product information should be consulted.
Patient advice: Use a form of birth control that does not contain hormones (diaphragm with spermicide, condoms with spermicide, a copper IUD)
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about leuprolide/norethindrone
Consumer resources
Other brands: Lupaneta Pack
