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User Reviews for Medroxyprogesterone

Also known as: Depo-Provera, Provera, depo-subQ provera 104

Medroxyprogesterone has an average rating of 4.5 out of 10 from a total of 2,347 ratings on Drugs.com. 31% of reviewers reported a positive experience, while 51% reported a negative experience.

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Summary of Medroxyprogesterone reviews 4.5 2,347 reviews

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Medroxyprogesterone

AB · Taken for 10 years or more · September 5, 2020

Depo-Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: “I have been on Depo for 10 years without missing a injection. I had no side effects and LOVED not having a period. Something in the drug has obviously been altered because I'm having a period now, and nothing else in my routine has changed. This began around February/March of this year (2020). I've still continued to get the injection, but am questioning what exactly has happened to the drug and why patients have not been informed about any changes to the drug.”

6 / 10
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JosieL84 · January 23, 2020

Provera (medroxyprogesterone) for Amenorrhea: “A drug I can rely on! I always get my period within 5 days of stopping Provera 10mg x 5 days. This time, it came on the morning of day 4. But get your diapers ready! It is extremely bloody! I am thankful for it kickstarting my cycle in hopes of a positive Frozen Embryo Transfer! I don't mind the heavy bleed and cramping. When you have infertility and amennorhea, a period can be a blessing, it can mean new hope for the coming cycle (I am a glass half full type person!)”

10 / 10
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Linkinslide · Taken for 1 to 6 months · May 23, 2021

Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: “I've been taking the provera 10mg once a day since March 20, 2021 because I have irregular bleeding and 2 fibroids. My period has not stopped or slowed down at all. Last month it was just seven days, but this month, it's been on for two weeks. It seems like it wants to stop but then I'll have spotting before full on bleeding and it seems to happen after I take the pill. I was told this medication would stop my period and correct the irregular bleeding but it has done nothing of the sort. I feel, if anything, it's causing me to continuously bleed.”

1 / 10
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Taza · Taken for 1 to 6 months · July 3, 2021

Depo-Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: “I’ve started the depo provera injection fairly recently 24 May 2021. I was on my period which I normally have for seven days but with this injection my period went from normal flow to a dark brown, slow flow which couldn’t fill a pad. To changing halfway in June to a medium heavy flow. I called the doctors in the early stages because when I read the symptoms it said spotting but not heavy flow period. When I spoke to her it was like speaking to someone who doesn’t want to hear you. Not helpful at all. It’s now July I’ve been bleeding for a total of 42 days and counting. Will I get the 2nd injection in August? Nope. Would I recommend it? Nope. It really mucks up your emotions It has made me cry over stupid things. I had this injection so I could have sex without fear of pregnancy have I been able to have sex no. My advice once again it’s not the one to get”

1 / 10
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Mandy · December 15, 2019

Provera (medroxyprogesterone) for Amenorrhea: “I missed my period for 3 months and was very worried and didn’t know what was going on in my system but after Provera for 10 days I didn’t start my period. But then after another 5 days my period just started. Just have patience after taking this drug - it really effective. I hope this helps someone”

10 / 10
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Christina d. · Taken for 1 to 6 months · June 9, 2020

Depo-Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: “I can't believe all the reviews I'm reading about the shot making you bleed for weeks or even months because now its happening to me. I got the shot for the first time in late April and I started to bleed about 2 and a half weeks ago. And I'm still bleeding. This really sucks. Being on a period everyday is not what I signed up for. I will NOT be getting it again and I just want my period to go back to normal. Would NOT recommend getting this to anyone!”

1 / 10
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GG · February 15, 2021

Depo-Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: “I have been on Depo Provera for 22 years. After my very first injection 22 years ago, I have had zero periods and zero breakthrough bleeding. Zero side effects. Nothing. This has been a blessing. I had my last Depo Shot on 1/12/21. My next one is not due until 3/30/21. Today I wake up and have bleeding. While I realize that this can be due to other causes, I was just reading that there are others experiencing this. Perhaps there is something wrong with a batch of the medication? Will see what happens from here and keep an eye on it.”

10 / 10
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Frequently asked questions

Ms.Queen · Taken for 1 to 6 months · September 18, 2020

Depo-Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: “I feel better knowing I'm not going through this horrible experience of Depo-provera alone. I loved the depo just because I didn't have periods over 5 years using this shot. And now to bleed every day longer than 10 days is very depressing. I would like to know what I can do to make this bleeding stop. This can't be healthy”

1 / 10
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Missy · Taken for 1 to 2 years · February 28, 2019

Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: “I have been on this med several times , I am 48 years old going through menopause and have had abnormal bleeding off and on for 2 years. From what I understand 10 days on this med is not going to make you stop bleeding. What it does is "clean" you out first before it thins the lining enough to stop the bleeding. When I take it I bleed worse for a couple weeks, clots come out and then it stops and stays stopped so all the ladies taking it for 10 days give it more time please. The cramps are bad during the "cleaning" phase also but trust me it will get better.”

10 / 10
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GG · January 4, 2021

Depo-Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: “I've been on Depo-Provera for over a decade with no side effects, no periods or breakthrough bleeding. I have never missed an injection, however 3 weeks before my next injection I'm bleeding. This is an unwelcome, painful surprise because I've been without a period for as long as I've been on this birth control which has been almost 14 years. Something has changed with the medication”

8 / 10
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Connie · June 22, 2019

Provera (medroxyprogesterone) for Amenorrhea: “I have PCOS and my doctor prescribed me with Provera for 14 days, 10mg per day and was told by my doctor that it will help me regulate my period. I remember taking it on May 17 and I was on it till May 31. I was told that I was gonna get my period after 3 days. I didn’t get it after that but I had light spotting a couple days after. I called my doctor she said I should get it very soon. Finally it came on June 9th it was still very light, days has passed and it started to get heavier. It’s June 21 now and I’m still bleeding. I have called my doctor to check with her if this is serious as I had never bled this much before of course it was very alarming. She told me that I had to wait until it subside and have an ultrasound. I am also experiencing mood changes, breakouts, cramps, breast tenderness, fatigue, dizziness, nausea and headaches, the side effects are not so bad but my main concern is the long period. Did anyone else had the same experience?”

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Amanda · Taken for 1 to 6 months · February 28, 2020

Depo-Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: “I got on the shot in early Nov 2019, it's now Feb 27th and I have been on a period since. Not a light period but a heavy "blood clot" type one. I'll never get this shot again, and I will not recommend it to anyone.”

1 / 10
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Kat · Taken for 1 to 6 months · February 10, 2020

Depo-Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: “Worst contraceptive ever. I had my first depo shot on the 9th of Jan. Approximately two weeks after I started spotting and then bleeding heavily. I am so mad that my doctor never indicated or told me about any of these side effects. I will not be going back for a second injection. Now, I feel like I am on a permanent menstrual cycle. If any of you ladies are really wanting to do something about this horrible drug, report it to the FDA. And also to Pfizer on their website. I believe this drug needs to be removed from the market. I don't think any woman wants to keep bleeding for months on end at a time.”

1 / 10
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OverTired · Taken for less than 1 month · May 31, 2020

Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: “I've been currently taking Provera 10mg for about 28 days now. At first it stopped the bleeding all together for the first week. Then I started to spot again and bleed. Now the bleeding is getting progressively heavier and the clots are getting larger, like they are huge. This is a nightmare. I'm having to empty my 25ml menstrual cup every hour or two. Hoping to get ahold of my OB by Monday. I'm feeling very weak and I have lots of cramping.”

2 / 10
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Bananamom · Taken for less than 1 month · October 4, 2020

Depo-Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: “I took Depo-Provera injection many years ago. I never had a period or spotting from the first shot. I was on it for 6 years no issues other than weight gain. I got the shot again on September 10, 2020. I started bleeding 10 days ago. The cramps are extreme to the point I don't want to get out of bed. Which is not possible, I have 3 children age 8, 2, and 1 and a stay at home mom. Over the counter medication does not help with pain. There are too many of us experiencing the same things and a lot of us have already taken depo before with no issues.”

1 / 10
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Tamara · Taken for 1 to 6 months · April 15, 2021

Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: “I am 48 years old and childless and started bleeding on January 2nd until February 12th. I went to the gynecologist and she prescribed 10mg provera for 21 days and my cycle regulated. Low and behoĺd I got pregnant with my first baby at the start of April. Its amazing! I have just begun a new journey and I look forward to every single step.”

10 / 10
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emma · Taken for 1 to 2 years · February 13, 2020

Depo-Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: “So I've been on this Depo-Provera shot since I was 16. I’m 18 now. I haven’t bleed on my period for 2 years. This past week I started to spot. Now I'm getting really heavy bleeding that’s bright red. It’s just a little odd that I’ve been on it for 2 years and haven’t bled at all and now all of the sudden I am. I am not sure if this is normal or not.”

5 / 10
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Anonymous · Taken for less than 1 month · December 26, 2019

Provera (medroxyprogesterone) for Amenorrhea: “I took Provera for 10 days at a dose of 10mg a day, prescribed by my fertility doctor with intentions to induce my period. My period was always regular up until recently. The side effects while on this drug were some pretty bad, mood swings, mild cramps on and off and breast soreness. A week after the dose ended and I still hadn’t gotten my period. Low and behold it arrived this morning. Thanks to this drug we can now continue our fertility journey. Have patience- it can really work. Now I’ve got a heavy period with horrid cramps- but it’s worth it!!!”

9 / 10
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Rachel · Taken for less than 1 month · September 5, 2019

Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: “I feel like everyone who left reviews here only left negative ones. But for me the provera pill helped me so much. I kept bleeding after my miscarriage at 8 weeks, for about 8 weeks - the bleeding was severe towards the end and I've had enough. My doctor gave me a 14 day supply of provera and I stopped bleeding after 1 pill. My cycle has been reset now, so this worked for me very well.”

10 / 10
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Keke · Taken for 10 years or more · May 22, 2020

Depo-Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: “I been on depo-provera for 20 years and was very happy but then when I love to out of state last year I start bleeding. I been bleeding for over 2 years now and I am so depress over this annoyance and my hubby is to. I really want sex but with the blood clots and non-stop bleeding I feel like I'm going crazy. I have tired everything the doctor has giving me bit it just won't stop and I'm sick of it. I'm mad and wish this bleeding just go away so I can try and be happy and work on my depression. Somebody please help me to stop this bleeding 2 years is too much.”

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Gladys · Taken for 6 months to 1 year · June 1, 2020

Depo-Provera (medroxyprogesterone) for Birth Control: “I only see the negative sides effects of depo-provera being listed. Well I started the depo mid last year (2019) and so far so good I haven't hard any challenges or side effects while on it. Before the injection I used to bleed heavily with painful cramps but since I started this, no cramps with lighter bleeding that lasts for up to 3 days. Mind you before I used to bleed for seven days. I think it's all about ones body just because it failed on you doesn't mean it will fail on another person, people are different”

9 / 10
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Belle · Taken for less than 1 month · January 7, 2021

Provera (medroxyprogesterone) for Amenorrhea: “So let's talk about Provera. I was put on this for not having a period for 10 months. Just remember that during the time you don't have a period in most cases your body is still producing that lining. I took it for a week (10mg a day) and got my period 3 days later. It is my far the worst period I've ever had. This is worse than any period I've had even the ones I had directly after giving birth. I've bled through pads and tampons multiple times and I'm only on day 4! I'm feeling nauseous and dizzy and weak, normal daily functions are hard at this point. I also feel very angry and withdrawn to the point of where I just want to be by myself and sleep. Oh not to mention the huge clots I've been passing. If this were considered a "normal period" I would have went to the hospital by now. The cramps are horrendous also. I will say if you are trying to get your period it does the job, just be prepared for one nightmareish period.”

3 / 10
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Summer2012 · Taken for 1 to 6 months · June 6, 2020

Depo-Provera (medroxyprogesterone) for Abnormal Uterine Bleeding: “I got the Depo-Provera in January - the only one I had. My heavy bleeding started the very next day and now 5 and a half months down the line I am still bleeding a heavy period everyday!! Doctors can not work out why or what is going on !!”

1 / 10
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Rosh · Taken for less than 1 month · December 7, 2019

Provera (medroxyprogesterone) for Amenorrhea: “PCOS!!! Irregular periods and trying to conceive for 2nd 1, I was prescribed provera 10mg for 10 days so that my progesterone level could be monitored and from what i read from day 3-7 you get periods. Today day 6 and still no periods :(”

5 / 10
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Chanty · Taken for less than 1 month · November 8, 2020

Provera (medroxyprogesterone) for Amenorrhea: “I was missing my period for a year and 6 months my doctor recommended it and I took provera for the 5 days ...had my period on schedule every month since then (4 periods now) I would recommend to anyone”

10 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.