Medroxyprogesterone Alternatives Compared
| Medroxyprogesterone | Mirena (levonorgestrel) | Nexplanon (etonogestrel) |
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| Medroxyprogesterone | Mirena (levonorgestrel) | Nexplanon (etonogestrel) |
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Prescription only
Prescribed for Abnormal Uterine Bleeding, Endometrial Hyperplasia - Prophylaxis, Amenorrhea, Endometrial Cancer, Birth Control, Endometriosis, Gender Affirming Hormone Therapy, Gender Dysphoria... View more |
Prescription only
Prescribed for Heavy Menstrual Bleeding, Birth Control. Mirena may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Birth Control. Nexplanon may also be used for purposes not listed in this medication guide. |
Related suggestions Birth Control
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| More about Medroxyprogesterone | More about Mirena (levonorgestrel) | More about Nexplanon (etonogestrel) | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Medroxyprogesterone has an average rating of 4.5 out of 10 from a total of 2469 ratings on Drugs.com. 30% of reviewers reported a positive effect, while 51% reported a negative effect. |
Mirena has an average rating of 6.1 out of 10 from a total of 2624 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 32% reported a negative effect. |
Nexplanon has an average rating of 5.0 out of 10 from a total of 4865 ratings on Drugs.com. 32% of reviewers reported a positive effect, while 43% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Medroxyprogesterone side effects |
View all Mirena side effects |
View all Nexplanon side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Medroxyprogesterone prices |
View all Mirena prices |
View all Nexplanon prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Depo Provera, depo-subQ provera 104, Provera | Other levonorgestrel brands include: Aftera, AfterPill, AfterPlan, Athentia Next, Curae, EContra One-Step, Fallback Solo, Her Style, Julie, Kyleena, Liletta, Morning After, My Choice, My Way, New Day, Next Choice One Dose, Opcicon One-Step, Option 2, Optionelle, Plan B One-Step, PostDay One-Step, SheWise, Skyla, Take Action View more |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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401 hours |
45 hours |
25 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 253 drugs are known to interact with Medroxyprogesterone:
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A total of 261 drugs are known to interact with Mirena:
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A total of 250 drugs are known to interact with Nexplanon:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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June 18, 1959 |
N/A |
July 17, 2006 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.