Skip to Content

Nexplanon (etonogestrel) Drug Interactions

A total of 256 drugs are known to interact with Nexplanon (etonogestrel).

  • 41 major drug interactions
  • 206 moderate drug interactions
  • 9 minor drug interactions

Show all medications in the database that may interact with Nexplanon (etonogestrel).

Check for interactions

Type in a drug name to check for interactions with Nexplanon (etonogestrel).

Most frequently checked interactions

View interaction reports for Nexplanon (etonogestrel) and the medicines listed below.

  • Adderall (amphetamine / dextroamphetamine)
  • amitriptyline (Elavil, Endep, Vanatrip)
  • amoxicillin (Amoxil, Trimox, Apo-Amoxi, Amoxicot, Moxatag, DisperMox, Moxilin, Wymox, Biomox)
  • biotin (Hair, Skin & Nails, Appearex)
  • bupropion (Wellbutrin, Wellbutrin XL, Wellbutrin SR, Zyban, Buproban, Budeprion, Aplenzin, Forfivo XL, Budeprion XL, Budeprion SR)
  • doxycycline (Vibramycin, Oracea, Monodox, Doxy 100, Doryx, Adoxa, Targadox, Morgidox, Acticlate, Vibra-Tabs, Doxy-Caps, Periostat, Doxy 200, Oraxyl, Doryx MPC, Doxy-D, Alodox, Adoxa Pak, Avidoxy, Adoxa TT, Adoxa CK, Ocudox, LymePak, Uracil, Mondoxyne NL, NicAzel Doxy, Doxy-Lemmon)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • hydroxyzine (Vistaril, Atarax, Hyzine, Vistazine, Rezine)
  • ibuprofen (Advil, Motrin, IBU, Children's Motrin, Proprinal, Advil Liqui-Gels, Ibu-8, Motrin IB, Motrin Childrens, Rufen, Childrens Ibuprofen Berry, IBU-200, Ibuprofen PMR, Advil Migraine, Ibu-Tab, Genpril, Menadol, Advil Children's, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, Addaprin, Motrin Infant Drops, NeoProfen, Caldolor, Motrin Pediatric, Haltran, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Nuprin, Advil Junior Strength, Actiprofen, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
  • Implanon (etonogestrel)
  • Lamictal (lamotrigine)
  • melatonin (Melatonin Time Release, SGard, Bio-Melatonin, Health Aid Melatonin, VesPro Melatonin)
  • metformin (Glucophage, Glumetza, Glucophage XR, Fortamet, Riomet)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • Peri-DS (casanthranol / docusate)
  • Plan B (levonorgestrel)
  • propranolol (Inderal, Inderal LA, Hemangeol, InnoPran XL, Inderal XL)
  • sertraline (Zoloft)
  • sumatriptan (Imitrex, Onzetra Xsail, Imitrex Nasal, Zembrace SymTouch, Zecuity, Alsuma, Sumavel DosePro, Tosymra, Imitrex Statdose)
  • Topamax (topiramate)
  • topiramate (Topamax, Trokendi XR, Topiragen, Qudexy XR, Topamax Sprinkle)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, ConZip, Zydol, Tramal SR, GenRx Tramadol, Zamadol, Ryzolt, Tramedo, Larapam SR, Tramahexal SR, Tramahexal, Zydol XL, Rybix ODT, Ultram ODT)
  • trazodone (Desyrel, Oleptro, Desyrel Dividose)
  • Tylenol (acetaminophen)
  • Vitamin B12 (cyanocobalamin)
  • Vitamin D3 (cholecalciferol)
  • Zoloft (sertraline)

Nexplanon (etonogestrel) alcohol/food interactions

There are 2 alcohol/food interactions with Nexplanon (etonogestrel)

Nexplanon (etonogestrel) disease interactions

There are 9 disease interactions with Nexplanon (etonogestrel) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Hide