Nexplanon Alternatives Compared
| Nexplanon | Mirena | Lo Loestrin Fe |
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| Nexplanon (etonogestrel) | Mirena (levonorgestrel) | Lo Loestrin Fe (ethinyl estradiol / norethindrone) |
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Prescription only
Prescribed for Birth Control. Nexplanon may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Heavy Menstrual Bleeding, Birth Control. Mirena may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Birth Control. Lo Loestrin Fe may also be used for purposes not listed in this medication guide. |
Related suggestions Birth Control (Contraception)
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| More about Nexplanon (etonogestrel) | More about Mirena (levonorgestrel) | More about Lo Loestrin Fe (ethinyl estradiol / norethindrone) | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
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No lower-cost generic available |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Nexplanon has an average rating of 5.1 out of 10 from a total of 4847 ratings on Drugs.com. 32% of reviewers reported a positive effect, while 42% reported a negative effect. |
Mirena has an average rating of 6.1 out of 10 from a total of 2595 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 32% reported a negative effect. |
Lo Loestrin Fe has an average rating of 5.6 out of 10 from a total of 1543 ratings on Drugs.com. 42% of reviewers reported a positive effect, while 37% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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Common side effects include:
See also: Nexplanon side effects in more detail. |
See also: Mirena side effects in more detail. |
See also: Lo Loestrin Fe side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Nexplanon prices |
View all Mirena prices and generic prices |
View all Lo Loestrin Fe prices and generic prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
Other levonorgestrel brands include: Aftera, AfterPill, AfterPlan, Athentia Next, Curae, EContra One-Step, Fallback Solo, Her Style, Julie, Kyleena, Liletta, Morning After, My Choice, My Way, New Day, Next Choice One Dose, Opcicon One-Step, Option 2, Optionelle, Plan B One-Step, PostDay One-Step, SheWise, Skyla, Take Action View more | Other ethinyl estradiol / norethindrone brands include: Alyacen 1/35, Alyacen 7/7/7, Aranelle, Aurovela 1.5/30, Aurovela 1/20, Aurovela 24 Fe, Aurovela Fe 1.5/30, Aurovela Fe 1/20, Balziva, Blisovi 24 Fe, Blisovi Fe 1.5/30, Blisovi Fe 1/20, Brevicon, Briellyn, Chabelina Fe, Charlotte 24 Fe, Cyclafem 0.5/35, Cyclafem 1/35, Cyclafem 7/7/7, Cyonanz, Dasetta, Dasetta 1/35, Dasetta 7/7/7, Estrostep Fe, Femcon Fe, femhrt, Finzala, Fyavolv, Gemmily, Generess Fe, Gildagia, Gildess 1.5/30, Gildess 1/20, Gildess 24 Fe, Gildess Fe 1.5/30, Gildess Fe 1/20, Hailey 1.5/30, Hailey 24 Fe, Hailey Fe 1.5/30, Hailey Fe 1/20, Jinteli, Junel 1.5/30, Junel 1/20, Junel Fe 1.5/30, Junel Fe 1/20, Junel Fe 24, Kaitlib Fe, Larin 1.5/30, Larin 1/20, Larin 24 Fe, Larin Fe 1.5/30, Larin Fe 1/20, Layolis Fe, Leena, Leribane, Loestrin 21 1/20, Lomedia 24 Fe, Melodetta 24 Fe, Merzee, Mibelas 24 Fe, Microgestin 1.5/30, Microgestin 1/20, Microgestin Fe 1.5/30, Microgestin Fe 1/20, Minastrin 24 Fe, Necon 0.5/35, Necon 7/7/7, Nexesta Fe, Norinyl 1+35, Nortrel 0.5/35, Nortrel 1/35, Nortrel 7/7/7, Nylia 1/35, Nylia 7/7/7, Ortho-Novum 7/7/7, Philith, Pirmella 1/35, Pirmella 7/7/7, Rhuzdah, Tarina 24 Fe, Tarina Fe 1/20, Taysofy, Taytulla, Tilia Fe, Tri-Legest, Tri-Legest Fe, Vyfemla, Wera, Wymzya Fe, Zenchent, Zenchent Fe View more | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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25 hours |
45 hours |
14 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 227 drugs are known to interact with Nexplanon:
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A total of 240 drugs are known to interact with Mirena:
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A total of 450 drugs are known to interact with Lo Loestrin Fe:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| First Approval Date | ||||||||||||||||||||||||||
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July 17, 2006 |
December 06, 2000 |
October 21, 2010 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.