Comparing Medroxyprogesterone vs Progesterone
| Medroxyprogesterone | Progesterone |
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| Medroxyprogesterone | Progesterone |
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Prescription only
Prescribed for Amenorrhea, Abnormal Uterine Bleeding, Endometrial Cancer, Endometrial Hyperplasia - Prophylaxis, Birth Control, Endometriosis, Gender Affirming Hormone Therapy . May also be... View more |
Prescription and OTC
Progesterone is a hormone that is used to treat conditions associated with ovulation, fertility, menstruation, menopause, or abnormal uterine bleeding. It may be used in gender affirming therapy to... View more |
Related suggestions Endometriosis
Amenorrhea
Gender Dysphoria
Endometrial Hyperplasia, Prophylaxis
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| More about Medroxyprogesterone | More about Progesterone | ||||||||||||||||
| Generic Status | |||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Medroxyprogesterone has an average rating of 4.5 out of 10 from a total of 2428 ratings on Drugs.com. 31% of reviewers reported a positive effect, while 51% reported a negative effect. |
Progesterone has an average rating of 6.5 out of 10 from a total of 71 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 23% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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See also: medroxyprogesterone side effects in more detail. |
Commonly reported side effects include:
See also: progesterone side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all medroxyprogesterone prices |
View all progesterone prices |
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| Dosage Form(s) Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Depo-Provera, depo-subQ provera 104, Provera | Crinone, Cyclogest, Endometrin, First Progesterone MC10, First Progesterone MC5, Gestone, Milprosa, Prometrium | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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401 hours |
1 hour |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category B
No proven risk in humans
Oral Formulations
Category N
Not classified
Excluding Oral Formulations See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 221 drugs are known to interact with medroxyprogesterone:
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A total of 180 drugs are known to interact with progesterone:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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June 18, 1959 |
November 01, 1974 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.