Comparing Medroxyprogesterone vs Prometrium
| Medroxyprogesterone | Prometrium |
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| Medroxyprogesterone | Prometrium (progesterone) |
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Prescription only
Prescribed for Amenorrhea, Abnormal Uterine Bleeding, Endometrial Cancer, Endometrial Hyperplasia - Prophylaxis, Birth Control, Endometriosis, Gender Affirming Hormone Therapy . May also be... View more |
Prescription and OTC
Prescribed for Endometrial Hyperplasia - Prophylaxis, Amenorrhea, Progesterone Insufficiency, Perimenopausal Symptoms, Uterine Bleeding, Premature Labor. Prometrium may also be used for purposes not... View more |
Related suggestions Amenorrhea
Endometrial Hyperplasia, Prophylaxis
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| More about Medroxyprogesterone | More about Prometrium (progesterone) | ||||||||||||||||
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| Ratings & Reviews | |||||||||||||||||
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Medroxyprogesterone has an average rating of 4.5 out of 10 from a total of 2428 ratings on Drugs.com. 31% of reviewers reported a positive effect, while 51% reported a negative effect. |
Prometrium has an average rating of 7.2 out of 10 from a total of 33 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 17% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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See also: medroxyprogesterone side effects in more detail. |
Common side effects include:
See also: Prometrium side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all medroxyprogesterone prices |
View all Prometrium prices and generic prices |
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| Dosage Form(s) Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Depo-Provera, depo-subQ provera 104, Provera | Other progesterone brands include: Crinone, Cyclogest, Endometrin, First Progesterone MC10, First Progesterone MC5, Gestone, Milprosa | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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401 hours |
1 hour |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category B
No proven risk in humans
Oral Formulations
Category N
Not classified
Excluding Oral Formulations See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 221 drugs are known to interact with medroxyprogesterone:
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A total of 180 drugs are known to interact with Prometrium:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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June 18, 1959 |
N/A |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.