Comparing Medroxyprogesterone vs Prometrium
| Medroxyprogesterone | Prometrium (progesterone) |
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| Medroxyprogesterone | Prometrium (progesterone) |
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Prescription only
Prescribed for Abnormal Uterine Bleeding, Endometrial Hyperplasia - Prophylaxis, Amenorrhea, Birth Control, Endometrial Cancer, Endometriosis, Gender Affirming Hormone Therapy, Gender Dysphoria... View more |
Prescription and OTC
Prescribed for Progesterone Insufficiency, Perimenopausal Symptoms, Uterine Bleeding, Endometrial Hyperplasia - Prophylaxis, Amenorrhea, Premature Labor. Prometrium may also be used for purposes not... View more |
Related suggestions Amenorrhea
Endometrial Hyperplasia, Prophylaxis
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| More about Medroxyprogesterone | More about Prometrium (progesterone) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Medroxyprogesterone has an average rating of 4.5 out of 10 from a total of 2474 ratings on Drugs.com. 30% of reviewers reported a positive effect, while 51% reported a negative effect. |
Prometrium has an average rating of 7.0 out of 10 from a total of 37 ratings on Drugs.com. 57% of reviewers reported a positive effect, while 16% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Medroxyprogesterone side effects |
View all Prometrium side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Medroxyprogesterone prices |
View all Prometrium prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Depo Provera, depo-subQ provera 104, Provera | Other progesterone brands include: Crinone, Cyclogest, Endometrin, First Progesterone MC10, First Progesterone MC5, Gestone, Milprosa | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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401 hours |
1 hour |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category B
No proven risk in humans
Oral Formulations
Category N
Not classified
Excluding Oral Formulations See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 256 drugs are known to interact with Medroxyprogesterone:
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A total of 221 drugs are known to interact with Prometrium:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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June 18, 1959 |
N/A |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.