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User Reviews for Progesterone

Also known as: Prometrium, Crinone, Endometrin, Progest, Menopause Formula Progesterone, Gestone, Prochieve, Cyclogest, First Progesterone MC10, First Progesterone MC5

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Condition Avg. Ratings Reviews Compare
Gender Dysphoria
1 review 0 medications
1 review 51 medications
Endometrial Hyperplasia, Prophylaxis
3 reviews 17 medications
Perimenopausal Symptoms
8 reviews 12 medications
1 review 103 medications
Progesterone Insufficiency
21 reviews 10 medications
Premature Labor
5 reviews 15 medications
Uterine Bleeding
6 reviews 10 medications
3 reviews 34 medications
Summary of Progesterone reviews 7.2 49 reviews

Reviews for Progesterone

Jules · Taken for 1 to 2 years September 11, 2019

For Progesterone Insufficiency: "I get freaky and can't remember what happened the next morning!"

Stat5150 · Taken for 1 to 6 months July 21, 2019

Prometrium (progesterone) for Progesterone Insufficiency: "I was given prometrium 100mg vaginal inserts 14 days out of the month along with estradiol patch 1mg for post menopausal symptoms. Prior to taking the prometrium, I was sleeping poorly and had stubborn weight around the belly I couldn't get rid of. After menopause, my figure changed and I gained a total of 10 lbs. Well...miraculously in a month on these, I lost 7 of those pounds! I am sleeping really well. Almost too much but maybe I needed it. My post menopause pants are getting too loose now and I think I'll have to unpack my high-rise jeans. Yay for prometrium!"

Lena July 16, 2019

For Progesterone Insufficiency: "On June 30, 2019 the pharmacy filled my prescription with a new generic drug from the manufacturer Akorn, for micronized progesterone 100 mg capsules, I take 300 mg each night. The generic for Prometrium from Akorn manufacturer-generic micronized progesterone, I started itching, now I am itching head to toe, also, I started having headaches and dizziness. I started having strange vivid dreams, not sleeping well, increased hot flashes. I have been taking Prometrium for many years, including other generics without any problems. I decided to stop taking the Akorn manufacturer generic micronized progesterone 100 mg capsules, and request a new prescription of Prometrium. The FDA wrote two warning letters to Akorn in 02/2018 and 06/2019, at the same plants where the medication was made. It may be contaminated with unknown foreign substances. My co-pay after insurance for a 90 day supply was $241.24 -for quantity of 270 capsules, 100 mg each. Very expensive for a generic that harmed me!"

Anonymous · Taken for less than 1 month July 13, 2019

Prometrium (progesterone) for : "I am 21 years old & in about 2 months gained 30 pounds although I worked out consistently & kept a clean diet. In addition I wasn’t sleeping, was retaining so much water I could not wear rings, & had horrific mood swings. However, my main problem was that I could no longer breathe, just speaking or walking felt like a marathon. For 8 months I have had an endless nightmare of appointments & tests with different medical specialist with no answers. After loss of all hope, I finally decided to see a hormone specialist. Because of a mild progesterone deficiency she recommended Prometrium for 6 weeks. I have been on 200 mg. of Prometrium for two weeks now & after only 3 days I started noticing my water retention lessening & I could breathe again! I can now workout better than I ever have been able to in my life, I sleep well, my stress levels are down, & my mood swings have subsided. This medication may have saved my life. Get your hormones checked!"

Laulee June 27, 2019

For Progesterone Insufficiency: "I started generic Prometrium for 10 days (for Premature menopause) then stopped because I broke out with itchy red bumps on my arms & legs. And, I still got hot flashes. When I stopped taking the progesterone (200mg at night) I started getting foggy brain again and terrible face aches and headaches. I restarted the generic Prometrium after a 5 day hiatus & after the red itchy bumps dried up. Now that I take the 200mg again no more head or face aches, and mild hot flashes finally disappeared. However, I continue to have vivid exhausting dreams every night that I take this. My sleep is NOT deep or restful. It is night after night of lucid, unwanted crazy dreams. This is an unreported side effect- I read other women experienced this, too. Also I get tiny somewhat itchy bumps under the skin on both of my hands. I wonder if the brand name Prometrium would have these bad effects on me as well..."

kat June 17, 2019

For Perimenopausal Symptoms: "Does anyone else have a problem taking the 100mg (red, round gel ball) capsule made by Akorn inc? I find the capsule keeps sticking to the sides of my throat. It really bothers me so I am going to see if there is another brand."

nightOwl March 18, 2019

For Progesterone Insufficiency: "Just four times a year? I'll take it. I need this Rx because I am on an estrogen patch for severe menopause symptoms. My dose is intra-vaginally, 200 mg, every other night for 12 nights, every 3 months - so 4 times per year. I never forget it because I begin my regimen at the start of each season. This method of progesterone by far right easiest method to tolerate for me. I won't use these hormones forever, but for right now, they help. The first few days, I get mild PMS symptoms - to be expected - then usually begin menstruating, which means it did its job. The PMS rises and falls with stress levels and other issues. I manage it by doubling my exercise routine, adding meditation; - high stress levels drive many PMS symptoms. I also switched to a Mediterranean diet a few years ago. I strongly recommend these things as they have a proven record of reducing PMS symptoms."

Nic · Taken for 1 to 6 months November 8, 2018

Crinone (progesterone) for Progesterone Insufficiency: "I used it for IVF/Frozen Embryo Transfer. I’m due with our baby any day now, it was super easy and convenient to use. I’d much rather do this than a intra-muscular shot into the butt every day."

Yogi · Taken for less than 1 month October 17, 2018

For Uterine Bleeding: "I was prescribed progesterone by my GYN for unusual, post menopause spotting coupled with the thickening of my uterine lining. He said it might reduce the uterine lining. Mine is 16 mm and normal is about 4 mm. He did not say how this drug would achieve this. I do not know if the lining will evaporate or if I will have a period. I have been on it for 30 days and the spotting has stopped. I will now have a vaginal ultrasound to see how thick the lining is. I can't imagine it would be thinner because how would that happen if there was no period. I give the drug high points because I slept really well and there were no odd symptoms, no breast tenderness, no real dizziness. I took it at bedtime of course."

Missy · Taken for 1 to 6 months July 12, 2018

Prometrium (progesterone) for Perimenopausal Symptoms: "I’m 46, perimenopausal, regular periods. I had very bad PMS and sore breasts for 2 weeks before period, and a serious inability to lose weight. I started this 3 months ago and I’m down 8 pounds, sleeping better and PMS is way better although it took the full 3 months for it to start helping. Now weighing 140 pounds at 5’7. I was very worried about weight gain on this, but it was opposite for me! I take 100mg at bedtime and stop it for 7 days during my period. I also started on Estro support (DIM) to lower estrogen as well. That also made a huge difference! Get your hormones tested so you know exactly what’s going on in your body!"

Frenchy · Taken for 1 to 6 months March 20, 2018

Prometrium (progesterone) for Uterine Bleeding: "Helps bleeding. Makes asthma worse. Helps me sleep."

Anonymous · Taken for less than 1 month January 27, 2018

For Gender Dysphoria: "I just recently started taking Prometrium and have been really happy with it: breast growth was a really pleasant surprise, considering I've been taking spironolactone and estradiol for almost 6 years. The reduction of anxiety has been fantastic, too, but it can make me really sleepy too"

Melba Bona · Taken for less than 1 month January 1, 2018

Prometrium (progesterone) for Uterine Bleeding: "I'm 50 and developed simple hyperplasia. Went eight months without a period and then had a three-week period that was very heavy and sent me to the ER for hemorrhaging. Doctor put me on Prometrium 100 mg daily for three months. After just two pills, I was having panic attacks during the day and at night. Could not take it. Current endometrial lining is 8.4mm after three weeks of bleeding, so likely will need a D&C. Will work with a naturopath to have some hormone testing done. It's likely that this dosage is just too high for me, but Prometrium doesn't come in a lower dose than 100 mg."

61778 September 24, 2017

For Perimenopausal Symptoms: "I take progesterone 100mg one a day and estradiol 1mg one a day. I have bad headaches, and start bleeding again when my period stop almost 2 years ago. My hot flashes slowed down but still there. Am I suppose to do these things? I need to know more from someone who takes those meds."

Baby2017 · Taken for less than 1 month January 27, 2017

For Progesterone Insufficiency: "I was prescribed progesterone in early pregnancy due to insufficiency. I switched pharmacies and this p-2 progesterone pill was a new brand that I was switched to. Two hours after taking the first pill (vaginally, as directed) I had spotting. This spotting continued for three days while I was on this pill. One day I didn't take it until the late afternoon and all morning had no bleeding. Then two hours after taking the pill I started bleeding again. I was far enough along in my pregnancy that when I brought this up to my doctor he said that I could safely stop taking it. Ever since I stopped taking this pill, the bleeding had since stopped too! I would not recommend this brand of progesterone."

Beachmom1974 December 23, 2016

Prometrium (progesterone) for Perimenopausal Symptoms: "I'm 42 years old and perimenopause has taken over my life. My estrogen dominance was so bad that for 8 whole days before I even started my period I was almost bed ridden. My breasts were so sore, it was as if they were engorged and I, at times, felt a low grade fever coming on. I have a 21 day cycle. I have one week a month that I felt pretty OK... Only one week a month!! Went to the Obgyn and begged for help. I'm now day 5 on prometrium. So far my head is clear, no boob pain, I'm awake not tired, not hungery either. I do have some uterine cramps every afternoon for some reason. I can't wait to see how my whole cycle will be. So far so good, very happy."

Shernandez0517 · Taken for 1 to 6 months December 12, 2016

Prometrium (progesterone) for Premature Labor: "Mild side affects such as fatigue and hunger, horrible headaches if not taken at all. Seems to work, however for the price paid for the medication seems like they could include a applicator like the ones they give with gels and OTC yeast meds etc. It's not fun or very easy trying to shove pills in your VAGAY with your fingers every single time you must use this medication."

boomer1171 November 22, 2016

Prometrium (progesterone) for Progesterone Insufficiency: "I was diagnosed with hyperplasia. I was experiencing very heavy, clotty periods for YEARS. I thought this was normal until I had a month long period. This pill is heaven sent. I have not had a period for about 8 months, have lost a tone of weight, have more energy than I have had in years and I would say the only side effect is tender breasts. I cannot guarantee this result for everyone but clearly I was no producing my own progesterone."

Shell99 · Taken for less than 1 month October 17, 2016

For Progesterone Insufficiency: "Hey everyone, told you I'd be back. Lol So I'm still on the AK 100mg. pill. I have lost over 3 pounds. I haven't changed anything since before taking this medication. In fact the only thing it changed is my mood, and stress levels, an of course my hormonal issue. I do have a tiny list of effects it's had on me so far. Ok so, my voice before was deeper an more loud, angry so to speak.(Which was because of too much testosterone in my system.) So my voice started to change 3 days after starting this pill. It gave me a slight sore throat at first. Then my voice would cut out, or crack. So embarrassing...but now I have a softer tone. My depression is much less, I'm much happier now an positive. Acne is gone now too. Btw I'm 38. An progesterone works."

Shell99 October 7, 2016

For Progesterone Insufficiency: "I'm on AK pill. My doctor said my weight problems an acne are from having no progesterone to regulate my hormones. An that it made my testosterone too high, which makes it hard to lose any weight. Took last night. Slept great. No bloat, an high energy. I'm happy so far. Can't say I have any bad side effects. I'll check back if I get any negatives."

Just an FYI. · Taken for 1 to 6 months September 5, 2016

Prometrium (progesterone) for Progesterone Insufficiency: "I've been taking Prometrium for about 4 months now, & for the most part have no side effects. It works like its suppose to and keeps my progesterone to where it needs to be. However, just an FYI you should always take it before bed with food & I mean lights out in bed to sleep not watching TV or playing on your phone/tablet. If you take Prometrium & not go to bed it will cause a euphoric (high) feeling which may be unsettling to some people & may cause panic, because it does feel really weird."

boomer0511 July 24, 2016

For Endometrial Hyperplasia, Prophylaxis: "I was diagnosed 5 months ago with hyperplasia. I had experienced extreme periods with clotting and 7-10 bleeding for over 5 years. I thought this was normal for women approaching menopause, it is NOT. I was also 30-40 Lbs. over weight. My gynecologist put me on progesterone pills and a few months later she did a D&C. She told me my hyperplasia was gone and the best benefit is that i have no periods. I can't say enough about this pill. I am beyond child baring years so no periods is such a bonus!"

savethetigers July 9, 2016

For Endometrial Hyperplasia, Prophylaxis: "I take this med because I use vivelle estrogen patch and need progesterone every 3 months to prevent uterine lining buildup. I take 200 intravaginally, every other day for 12 days - 6 doses total - every 3 months. At first dose, I was slammed with drowsiness, lower back pain, hot flashes at night, restless sleep and weakness in legs. I had cramps, but did not get a period. By the last dose, the side effects were better. but still it was no picnic. It's a small price to pay however for being able to take vivelle dot and get estrogen, and as far as I understand, the easiest way to take progesterone as I don't want a uterine implant."

Maureen2 April 26, 2016

For Progesterone Insufficiency: "The first two years on 100 mg were ok with a very rough 3 month adjustment period of feeling emotionally and physically completely wacked out. After two years I started feeling menopausal symtoms of brain fog again so started taking 200 mg. This is my second month, emotional roller coaster angry outbursts, racing heartbeat, no sleep! I am giving it another month to see if things Will get to normal like before. Maybe I have to go through this every several years, part of getting older."

Anonymous · Taken for less than 1 month April 18, 2016

For Uterine Bleeding: "I am 44 years old and taking AK2 generic for Prometrium for unusual uterine bleeding. The doctor put me on this to stop my irregular bleeding but so far after 4 days of taking I am still bleeding with some clots. I am supposed to take this for 12 days. He said my progesterone levels were really low and the endometrium had built up too much in my uterus. The first time I took it I got really dizzy and sleepy so now taking at night. I have had bad headache on two different occasions and fast heartbeat and definitely feel brain fog and can't think. This medicine is no fun. I had normal cycle up until a month and a half ago but a few months before that noticed reduced cycle so having low hormonal levels I guess."


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