Progesterone Alternatives Compared
| Progesterone | Prometrium | Endometrin |
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| Progesterone | Prometrium progesterone | Endometrin progesterone |
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Progesterone is a hormone that is used to treat female conditions associated with ovulation, fertility, menstruation, menopause, or abnormal uterine bleeding. It may increase the risk of blood clots... View more |
Prescribed for Endometrial Hyperplasia - Prophylaxis, Amenorrhea, Perimenopausal Symptoms, Progesterone Insufficiency, Uterine Bleeding, Premature Labor. Prometrium may also be used for purposes not... View more |
Prescribed for Endometrial Hyperplasia - Prophylaxis, Amenorrhea, Perimenopausal Symptoms, Progesterone Insufficiency, Uterine Bleeding, Premature Labor. Endometrin may also be used for purposes not... View more |
Choose a suggestion below Premature Labor
Perimenopausal Symptoms
Progesterone Insufficiency
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| More about Progesterone | More about Prometrium (progesterone) | More about Endometrin (progesterone) | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
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Prescription and OTC |
Prescription and OTC |
Prescription and OTC |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Progesterone has an average rating of 6.7 out of 10 from a total of 67 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 19% reported a negative effect. |
Prometrium has an average rating of 7.6 out of 10 from a total of 29 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 11% reported a negative effect. |
Be the first to share your experience with this drug. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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Commonly reported side effects include: abdominal cramps, depression, dizziness, headache. See the full progesterone side effects document. |
Common side effects include: abdominal cramps, dizziness, headache. See the full Prometrium side effects document. |
See the full Endometrin side effects document. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all progesterone prices |
View all Prometrium prices and generic prices |
View all Endometrin prices and generic prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Crinone, Cyclogest, Endometrin, First Progesterone MC10, First Progesterone MC5, Gestone, Milprosa, Prometrium | Other progesterone brands include: Crinone, Cyclogest, Endometrin, First Progesterone MC10, First Progesterone MC5, Gestone, Milprosa | Other progesterone brands include: Crinone, Cyclogest, First Progesterone MC10, First Progesterone MC5, Gestone, Milprosa, Prometrium | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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1 hour |
1 hour |
1 hour |
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| CSA Schedule** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category B
No proven risk in humans
Oral Formulations
Category N
Not classified
Excluding Oral Formulations See the full Pregnancy Warnings document. |
Category B
No proven risk in humans
Oral Formulations
Category N
Not classified
Excluding Oral Formulations See the full Pregnancy Warnings document. |
Category B
No proven risk in humans
Oral Formulations
Category N
Not classified
Excluding Oral Formulations See the full Pregnancy Warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 173 drugs are known to interact with progesterone:
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A total of 173 drugs are known to interact with Prometrium:
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A total of 173 drugs are known to interact with Endometrin:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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| First Approval Date | ||||||||||||||||||||||||||
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November 01, 1974 |
May 14, 1998 |
June 21, 2007 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient resources | ||||||||||||||||||||||||||
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N/A |
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| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.