Comparing Progesterone vs Prometrium
Progesterone |
Prometriumprogesterone |
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Prescribed for Progesterone Insufficiency, Endometrial Hyperplasia - Prophylaxis, Amenorrhea, Perimenopausal Symptoms, Uterine Bleeding, Premature Labor. May also be prescribed off label for... more |
Prescribed for Progesterone Insufficiency, Endometrial Hyperplasia - Prophylaxis, Amenorrhea, Perimenopausal Symptoms, Uterine Bleeding, Premature Labor. Prometrium may also be used for purposes not... more |
Choose a suggestion belowAmenorrhea
Premature Labor
Perimenopausal Symptoms
Progesterone Insufficiency
Endometrial Hyperplasia, Prophylaxis
Uterine Bleeding
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Prescription and OTC |
Prescription and OTC |
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Ratings & ReviewsRecent helpful reviews |
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7.3
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7.8
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Drug Class |
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Side Effects |
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Commonly reported side effects include: abdominal cramps, depression, dizziness, and headache. See the full progesterone side effects document. |
Common side effects include: abdominal cramps, dizziness, and headache. See the full Prometrium side effects document. |
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Pricing and Coupons* Prices are without insurance |
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Generic Availability |
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Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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Crinone, Cyclogest, Endometrin, First Progesterone MC10, First Progesterone MC5, Gestone, Menopause Formula Progesterone, Prochieve, Progest, Prometrium more... | Other progesterone brands include: Crinone, Cyclogest, Endometrin, First Progesterone MC10, First Progesterone MC5, Gestone, Menopause Formula Progesterone, Prochieve, Progest more... | ||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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1 hour |
1 hour |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category B
No proven risk in humans
Oral Formulations
Category N
Not classified
Excluding Oral Formulations See the full Pregnancy Warnings document. |
Category B
No proven risk in humans
Oral Formulations
Category N
Not classified
Excluding Oral Formulations See the full Pregnancy Warnings document. |
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FDA Alerts |
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N/A |
N/A |
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Drug Interactions |
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A total of 208 drugs are known to interact with progesterone:
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A total of 208 drugs are known to interact with Prometrium:
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Alcohol/Food/Lifestyle Interactions |
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Disease Interactions |
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First Approval Date |
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May 11, 1978 |
May 14, 1998 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
For Progesterone Insufficiency The first two years on 100 mg were ok with a very rough 3 month adjustment period of feeling emotionally and physically completely wacked out. After two years I started feeling menopausal symtoms of brain fog again so started taking 200 mg. This is my second month, emotional roller coaster angry outbursts, racing heartbeat, no sleep! I am giving it another month to see if things Will get to normal like before. Maybe I have to go through this every several years, part of getting older.