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Medroxyprogesterone User Reviews & Ratings (Page 3)

Brand names: Provera, Depo Provera, depo-subQ provera 104

Medroxyprogesterone has an average rating of 4.5 out of 10 from a total of 2,471 reviews on Drugs.com. 30% of reviewers reported a positive experience, while 51% reported a negative experience.

Reviews for Medroxyprogesterone

Commonly mentioned side effects
  • Upw...
  • Taken for 10 years or more
  • October 13, 2013

For Endometriosis "I have been on Depo now for over 20 years - I should be paid to be their poster child. It was the miracle medicine for me and my body. After 10 horrific years of monthly hell, I started Depo. Immediately, the periods went away, my hormones balanced and I literally regained my life. I have had no long-term effects, no weight gain, no side effects at all. For the right person, this works amazingly well. For others, it does not. But it IS worth a try!"

10 / 10
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  • Ado...
  • February 21, 2020

For Abnormal Uterine Bleeding "I got this shot back in July. I went to the clinic for Depo Provera, and I really thought this was gonna help. I guess I was wrong. Ever since August, I have had irregular bleeding but not a period, just spotting and bleeding that happens at random times, and I always get blood on my underwear, and I don’t want to wear pads every single day. It’s been 7 months now, and I’m still having this problem. I know it’s normal to have irregular bleeding, but it should have stopped by now. This shot has been no help, and I’m always having cramps and bleeding, and I’m miserable. And if I stop the shot, I’ll bleed for even longer, and I really don’t want that. I don’t know what to do to make my periods regular and make my long periods never happen again. I don’t know if I should switch to the IUD 'cause I’ll probably have more side effects, and I’m sick of it. Never should have gotten this shot. Big regret."

2 / 10
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57 Report
  • Cee...
  • October 14, 2019

For Abnormal Uterine Bleeding "I bled for 3 months straight with blood clots that were as big as a strawberry. The doctor put me on Provera to stop my period, the dose was 2 pills a day for 30 days. It worked... Then the next month, I didn't bleed for 2 months. The doctor put me back on Provera to start my period for 10 days, and it worked again."

10 / 10
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57 Report

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Frequently asked questions

  • spa...
  • March 5, 2011

For Abnormal Uterine Bleeding "I was having severe bleeding with large clots which lasted for 3 weeks. Finally, I saw the doctor and he gave me 10mg for 10 days. This is day 9. I stopped bleeding 2 days ago. I love this medicine, really. I'm hungry more often, but that's okay. Unsure what will happen when I stop taking it."

10 / 10
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119 Report
  • Ove...
  • Taken for less than 1 month
  • September 14, 2019

For Abnormal Uterine Bleeding "I started bleeding July 15, and it’s now Sep 14. I went to my doctor, they did an ultrasound, they said everything looked fine, blood work came back fine, and that sometimes it’s just the way it is, not knowing why I’m bleeding so much! Anyways, I threw a fit with the doctor, told her bleeding during intercourse and so much is not normal! She tried to tell me it was the positions we were doing, and I said no, I just want to know why. So she prescribed Provera 10 mgs, 1 tablet a day for 10 days. I am now on day 6, and the bleeding went from a little to so heavy I am changing my pads every hour! My cramps are unbearable, and there are so many blood clots! I just emailed my doctor to see what she says, fingers crossed that she can help give me answers!"

2 / 10
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  • Jmo...
  • Taken for less than 1 month
  • July 28, 2020

For Amenorrhea "I have PCOS and haven’t had regular (if any at all) periods for 2 years since coming off the contraceptive pill. Doctor prescribed me Provera for 10 days, and 2 days after finishing this 10-day course, I got my period. During the 10 days, I had a little breast tenderness, cramping, and moodiness, but very mild."

9 / 10
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  • JPe...
  • Taken for less than 1 month
  • January 27, 2020

For Amenorrhea "Took 10 mg Provera for 7 days for fertility reasons. Will NEVER take this medication again. I got such severe anxiety to the point where I ended up going to the ER because I thought something was wrong with me. I have never had such emotional instability in my life. About 3 weeks after taking the last pill, my panic attacks finally subsided. Also, my vision is all messed up now, and I am having muscle twitches. I did get my period, but was too bothered by all the Provera side effects that I didn’t end up going through with the Clomid."

1 / 10
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60 Report
  • Anonymous
  • September 14, 2014

For Abnormal Uterine Bleeding "I got Depo-Provera on June 10 at the hospital after giving birth to my daughter. Today is September 15 and I have not stopped bleeding at all! I also have two friends who have the same problem. This shot is terrible!"

1 / 10
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91 Report
  • Lee...
  • November 5, 2014

For Abnormal Uterine Bleeding "I thought the shot would be easy due to the fact of taking it every three months compared to the pill taking it every day, but the shot does not work for my body! I have been bleeding for over a month now. I am going back to the pill."

7 / 10
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95 Report
  • Anonymous
  • Taken for less than 1 month
  • May 7, 2019

For Abnormal Uterine Bleeding "Good evening, I stated my cycle like normal, only it lasted over a month. I freaked and went to the doctor because I was going insane. Got given a 14-day course of Provera, and I've been taking it for 2 days now, and the bleeding has stopped completely. I'm scared that if I stop taking it, I'll start to bleed again. I have to go back to get the ultrasound to figure out what happened. I've always had irregular periods, but normally I just would skip 3 or 4 months and start lasting 4-5 days most of the time, it's stress. This time it started and was beyond heavy. Not a lot of pain, though. I wish everyone hope for the madness we all share. Thanks for the comments. It's helped me a lot."

10 / 10
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54 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • June 10, 2020

For Abnormal Uterine Bleeding "I got my first Depo-Provera shot the third week of October 2019. It is now June, I've had 4 shots, and I’ve bled almost every day. Sex is painful because progesterone makes me dry, and I’m bleeding all the time. Almost 9 months straight of bleeding. I want to stop, but I’m trying to wait for the 12-month mark where they said bleeding stops. We will see."

1 / 10
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49 Report
  • Kin...
  • July 14, 2019

For Birth Control "Please do not use this horrible injection. As a medical scientist, I cannot believe how Depo-Provera passed the human trials and is on the market despite all the life-threatening side effects. I was hospitalized twice with severe bloating and kidney pain. It caused water retention (edema) all over my body, feet, legs, face, and abdomen! Constant dizziness, nausea, and cramps to the point that I can't function at work or home. This injection should not be on the market! It really ruined my life and I don't want anyone else to experience this. The FDA has a website where you can report all the adverse side effects of any medication, and it encourages people to report by either calling them or submitting an online form. Please, whoever reads this, if you have issues with Depo, go now to the FDA's website and complain about the horrible side effects you have experienced. The FDA will investigate the safety of this drug and potentially retract it from the market! It is our human right to safe medication, and this drug violates that right."

1 / 10
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55 Report
  • Anonymous
  • May 31, 2020

For Abnormal Uterine Bleeding "On Depo-Provera, I have been bleeding 4 weeks straight, nonstop!! I'm so crampy and wasn't bleeding up until I had the shot!! I had my son 10 weeks ago, so decided to try this and what a REGRET!!!! Is there a bad batch or something?! As I had the shot a few years back and never had this problem."

1 / 10
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  • TIR...
  • Taken for 6 months to 1 year
  • June 1, 2020

For Abnormal Uterine Bleeding "I started the depo at my 6-week check-up after my 4th child. I get it every 3 months and have received a total of 3 shots so far. I have been bleeding with a light period ever since the day I first got it. It's not as heavy as my usual period, but it's enough to have to always wear a pad."

4 / 10
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  • Rel...
  • Taken for less than 1 month
  • August 1, 2015

For Abnormal Uterine Bleeding "I was bleeding heavily for a month with extremely large blood clots that made it difficult and stressful to even leave the house. It was seriously affecting my quality of life and emotional well-being. My doctor prescribed Provera 10mg twice a day for ten days. After the second dose, the blood clots had completely disappeared. By the third dose, no bleeding at all. This medicine was like a miracle for me. I am happy to have my life back. I noticed I am having a headache, but it's not that bad. I'll take a headache any day over the suffering I endured with that excessive bleeding/clotting."

10 / 10
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79 Report
  • Ney...
  • May 30, 2013

For Abnormal Uterine Bleeding "I'm 18 years old. I never been on any other birth control but the 3 months on Depo-Provera... I bled for 2 months as well as depression. I was PMSing the full 2 months. Caused problems in my relationship because of it."

1 / 10
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103 Report
  • gat...
  • March 16, 2016

For Amenorrhea "I've always had VERY irregular periods due to kidney failure. I'm 22 years old and have gone as long as 6 years without a period. The first time I was prescribed Provera, I took 1 10 mg pill a day for 10 days. It took 2 weeks to get my period. I was so excited because I didn't think it was going to work for me. My period came back for 6 months without missing a beat. After it stopped coming, I had to redose and I'd get it for another 6 months at a time. I was having the worst time falling, but finally a miracle happened for me! If it wasn't for Provera giving me my period, I'm almost certain I wouldn't be holding my baby girl in my arms. I would give it a 10 rating if it weren't for me having to redose so often."

9 / 10
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72 Report
  • Key...
  • December 20, 2019

For Abnormal Uterine Bleeding "I never comment on stuff like this, but I must share my experience to help other women who have also had a bad experience with Depo Provera. I will get straight to it. I took the shot October 15, 2019, I stopped bleeding this morning. I purchased evening primrose from GMC, 1300 gel capsules, and I take 3 gel ibuprofen. I started taking the primrose after reading another post, and she stated she stopped bleeding in one day. I was tired of the doctor telling me, 'You have to wait for it to get out of your system.' I took matters into my own hands. Because of one of you ladies, I stopped bleeding. I will continue to take them until there is not a dot of blood left in my pad. Like I said, I take 1300 evening primrose. I have seen women take a higher dose, this dose works for me, and I take 600mg ibuprofen. I wouldn’t recommend taking that dose every day, use at your own discretion. NSAIDs are nephrotoxic. This works for me, and I don’t plan on taking the NSAIDs for too much longer."

8 / 10
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47 Report
  • Man...
  • Taken for 1 to 6 months
  • September 21, 2020

For Abnormal Uterine Bleeding "I got the 3-month Depo Provera injection. I experience irregular bleeding (having periods after every 2 weeks and spotting in between). This occurred for 3 months 'on the Depo Provera.' I did not go back for another shot because I switched to a copper IUD straight after the 3 months were over. I bled every single day (and not spotting) for nearly 3 months and 2 weeks. I guess it took nearly three months for the shot to wear off for the bleeding to stop completely. Worst nightmare. Was always tired, hair started to fall, experienced depression, low sex drive. I discouraged all my friends from taking this."

2 / 10
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42 Report
  • Dre...
  • March 9, 2015

For Abnormal Uterine Bleeding "I have been on Depo Provera since Dec. 6, 2015. Started bleeding on January 6, 2015, and it hasn't stopped since then! I had my second injection last Saturday, and I'm hoping that the bleeding will stop. It's effective in preventing pregnancy, but it's greatly affecting my sex life."

6 / 10
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  • Tan...
  • July 7, 2019

For Abnormal Uterine Bleeding "I’m a 27-year-old woman. I was diagnosed with PCOS at age 25, but always had irregular periods. Last May, I had a tube removed because it ruptured due to ectopic pregnancy. Around April, I missed my period, and it did not come for a month and a half. Then I started spotting for weeks. I finally went to the doctor, and they prescribed a birth control pill, 2 a day for 2 weeks, which did not work and caused the bleeding to get heavier after I finished the pills. It also caused me to have lower back pain, tender breasts, and diarrhea every day. Now I’m on Provera 10 for 10 days. Currently, on day 3, the cramps are horrible, and the bleeding is super heavy, and I still have all the same symptoms, plus a headache similar to a hangover. I am so tired of bleeding and being told it’s normal. I feel so depressed and hopeless. I’m going to stick with it though, because it’s my only hope atm."

2 / 10
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51 Report
  • JFa...
  • Taken for less than 1 month
  • November 10, 2019

For Amenorrhea "Took Provera 10 mg for 7 days. Then waited for withdrawal bleed, which seemed like forever. By day 9, I called GYN, panicked, thinking it wasn’t working, she said it could take up to 14 days after taking the last pill to work. Was getting discouraged, set up an appointment with GYN for the 14th day to discuss my other options, BUT on day 11, I started my flow! Be patient, unlike myself, it really does work! Will be taking Clomid again after 5 days, which has given me more side effects in the past than Provera did. Took at night before bed with little side effects."

9 / 10
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54 Report
  • Anonymous
  • Taken for 10 years or more
  • March 4, 2021

For Abnormal Uterine Bleeding "I have been on Depo for twenty years and today have a full-blown period. I mean, horrible cramping and all. I have never once had breakthrough bleeding or even a drop in 20 years. I received my injection on Jan 4th."

10 / 10
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42 Report
  • Sha...
  • Taken for 1 to 6 months
  • September 21, 2020

For Birth Control "I have been on this drug close to two months, and I haven't stopped bleeding. I was prescribed a medication to stop the bleeding, and it didn't work. I wish there was a way to get this drug out of my system now."

1 / 10
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43 Report
  • Sun...
  • Taken for less than 1 month
  • July 21, 2021

For Amenorrhea "I had irregular periods all through 2020, then in 2021 I missed 4 periods in a row. I took Provera 10 mg for 10 days. On the 6th day after my last pill, my period came, yay!!! But 9 days later, I’m still bleeding. I don’t know how much longer I’ll have to bleed for, but the bleeding is normal with zero cramps. I recommend Provera for every lady out there battling Amenorrhea and irregular periods."

10 / 10
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35 Report

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