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Medroxyprogesterone User Reviews & Ratings (Page 4)

Brand names: Provera, Depo Provera, depo-subQ provera 104

Medroxyprogesterone has an average rating of 4.5 out of 10 from a total of 2,471 reviews on Drugs.com. 30% of reviewers reported a positive experience, while 51% reported a negative experience.

Reviews for Medroxyprogesterone

Commonly mentioned side effects
  • Sun...
  • Taken for less than 1 month
  • July 22, 2018

For Abnormal Uterine Bleeding "My doctor put me on 10 mg Provera for two weeks due to menorrhagia. I had been bleeding heavily for two weeks when I started with the medication. Provera slowed my vaginal bleeding down to a medium flow, sometimes even a light flow, but it never stopped the bleeding. On the 14th day and last day of Provera, I started getting bad cramps that lasted for two and a half days. A day after I stopped with Provera, it was like someone turned on a faucet. Blood is gushing out of me. It’s like when you sit down and urinate, only it’s blood gushing out of my uterus. It was really scary until I came on here and saw that extremely heavy bleeding seemed to be normal when you first stop with Provera. Luckily, I’ve been off work the last two days and stayed in bed or on the toilet. The third day of being off Provera is tomorrow, which is also when I’m back at work. Hoping the bleeding will have slowed down a little bit by then."

5 / 10
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  • Rav...
  • October 4, 2014

For Abnormal Uterine Bleeding "My shot ended in August, and since then I have been constantly bleeding. I went in and saw a doctor about this issue, and they told me to take 3 pain relievers 4 times a day to stop the bleeding. I have tried that, and I am still bleeding. I will never get on this shot again. I have been on this shot before and never had issues like this."

1 / 10
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83 Report
  • Vic...
  • Taken for 1 to 6 months
  • April 1, 2019

For Birth Control "I would rate this drug 0 out of 10 if possible. Yes, it helped with my periods (I didn’t have them, just a bit of spotting), and I didn’t get pregnant! I had my second shot two months ago, and I won’t be going for a third. I am EXTREMELY moody, depressed, anxious/nervous, and I always feel on edge. I have also been getting paranoid about my relationship. Has anyone else experienced paranoia on this injection? Definitely do NOT recommend!!!!!"

1 / 10
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Frequently asked questions

  • Lac...
  • February 19, 2015

For Abnormal Uterine Bleeding "I've been taking this shot since October. I've been bleeding nonstop since December. It went from a 2-week period to a 2-month period. I've taken meds to help & nothing! This is horrible. It's like I'm on the shot for no reason."

2 / 10
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  • SHa...
  • Taken for less than 1 month
  • January 24, 2020

For Amenorrhea "Taking Provera was the worst decision I ever made. My period was very heavy. I was told by my OBGYN that it was going to delay my period, but it made me worse than I was before taking it. Day 5 of my period and still a heavy flow. Still have pain. I found out after taking it I will have another period 3-7 days after having a 10-day cycle. I can’t have this much bleeding."

1 / 10
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  • Zob...
  • Taken for 2 to 5 years
  • March 27, 2021

For Abnormal Uterine Bleeding "I’ve been on the Depo injection for 3+ years and have never had any bleeding. Until my last injection on 23rd Feb 2021, I have been brown spotting for 1 week and have woken up this morning with full-blown red blood. I was so scared, and I’m so glad I found this forum, which shows it’s been happening to a lot of other women recently."

3 / 10
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  • Eri...
  • March 22, 2013

For Birth Control "I've been on Depo Provera for about a month now, and I absolutely love it! I haven't had ANY bleeding, no cramps, no headaches or dizziness, no mood swings, no swollen or tender breasts, no weight gain, nothing! I still have a sex drive and I feel perfectly normal. Most people with good side effects don't think to share their experience, so remember that everyone's body is different and your experience might be like mine!"

10 / 10
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  • Lee...
  • June 12, 2019

For Abnormal Uterine Bleeding "I'm 41 years old. I've been taking Provera for a month now. It stopped my bleeding the first month, but then it came back in full force, and I haven't stopped bleeding yet, and it's been a month. I was put on it because of my anemia and fibroids because my blood was low due to the loss of blood. I have been feeling very weak, bleeding heavily, and having horrible pain, going back to the doctors due to the pain and bleeding. I cannot take the pain, and I stopped taking the pill."

1 / 10
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  • bar...
  • June 4, 2014

For Abnormal Uterine Bleeding "I've been on Depo-Provera for 2 years this month. It was great! Had little to no periods, light spotting for a week before I had gotten my next shot. Didn't have to worry about taking pills daily. I had no side effects at all. I was actually losing weight. But, the last shot I had back in March, they informed me that there was a new type of Depo formula that took the place of the Depo that my body was used to. Ever since then, my period has not stopped. I gained 20 pounds in one week of water weight. My cramps have been terrible to where I can't eat. I feel as though I'm pregnant at all times. I go Tuesday to either get checked to see if I need to be off it. Anyone else experienced this since they've changed it?"

8 / 10
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  • Rey...
  • Taken for 1 to 6 months
  • February 26, 2015

For Abnormal Uterine Bleeding "I got the Depo shot in October 2014. It is now February 2015, and I have been either spotting or full-on bleeding since then. I can't have sex because I start to bleed as if my period just started. I've been on and off the Depo for four years, and this is the first time I've had a bad experience with it. I also gained 25 pounds since October, but I eat healthily and go to the gym regularly."

2 / 10
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  • Anonymous
  • Taken for less than 1 month
  • May 7, 2014

For Abnormal Uterine Bleeding "I was bleeding for 7 weeks lightly, and then all of a sudden it came, and I was passing large clots and a lot of blood. My doctor put me on Provera 10mg twice a day. I had a horrible headache and felt tired, but my period did stop, which is great."

7 / 10
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  • Cri...
  • Taken for 1 to 6 months
  • February 12, 2014

For Abnormal Uterine Bleeding "I've been on this for a few months. I'm very bad at remembering to take the pill every day at the same exact time, so I figured the shot would be perfect. And I know it's still a little too early to determine whether or not I like it. I got my period in December, and she administered the shot. I haven't stopped bleeding since, and it's almost March! I spoke with my doctor, and she told me it was totally normal and it was my body getting used to the medication, but I very much dislike it. I've been VERY moody, and I get so turned off by food that sometimes I just go through the day drinking fluids. This has only been from one shot, but I'll see where it goes. If it continues to go downhill, I have to switch back to the pill."

3 / 10
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  • Pan...
  • Taken for less than 1 month
  • February 1, 2020

For Abnormal Uterine Bleeding "I was prescribed these to delay my period for 3 weeks while on holiday, they delayed it for about 7 days, but I still got my period, then had heavy, irregular bleeding for approximately 2 months. I have PCOS, so my periods are extremely irregular but only last 5 days and are light to normal. This medication wasn't any good for me at all, and along with the spontaneous, heavy bleeding, I had terrible pain and large clots. I'll never take them again. I've had northisterone in the past to delay my period, and they were brilliant. This is just my experience, and every woman is different."

3 / 10
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  • Mel...
  • Taken for 1 to 6 months
  • November 4, 2019

For Abnormal Uterine Bleeding "I have been taking Provera since July 2019. I have had heavy periods for years and started a very irregular pattern in Dec 2018. The doctor put me on it to thin out my lining and correct a hormonal imbalance. I've had one period that was very light in Sept and haven't had another one. I am having a D&C for a polyp removal and am hoping I am finally done with heavy bleeding. Provera has saved my sanity."

10 / 10
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  • sie...
  • Taken for less than 1 month
  • August 11, 2018

For Amenorrhea "So I was prescribed Provera because I haven’t had my period in over a year, and I had to take it for 5 days. I’m not sure of the dose, I think 5 or 10. I started on the 24th of July and stopped on the 28th. During the 5 days, I was getting like PMS and light cramping. After I stopped, it took me 6 days to finally get my period, and it was heavy. Like SUPER heavy. My periods are usually heavy, so it didn’t really faze me, and so were my cramps, but it’s horrible when you haven't had a period in a while, you kind of forget the pain. So I’m almost on day 9 of my period, and the flow is still going strong. I’m worried it won’t ever stop. My cramps are so bad it radiates to my back and down my legs, and it is constant all day, I don’t know what to do. My emotions are all over the place as well, I get in an uncontrollable rage and extremely sad throughout the day. Hopefully, it stops."

4 / 10
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  • And...
  • January 29, 2021

For Amenorrhea "I took Provera because I have irregular periods, and I was told it would help induce my periods. I took 10 mg for 10 days. I had a mild headache the first two days, then my body got used to it. I had my period a day after my 10th pill, and it was regular, nothing abnormal. I would recommend it."

9 / 10
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33 Report
  • Sto...
  • August 3, 2015

For Abnormal Uterine Bleeding "If I could give this shot a 0 rating, I would. Let's start with I've always had a normal period before this unexplained side effect of a shot. This shot was administered to me in April, and I didn't stop bleeding until July 31st. After doing my own research and taking matters into my own hands, it has finally stopped. I went to the doctor countless times trying to figure out how to stop the bleeding. I took (BLACKSTRAP MOLASSES), if I could type that in bold letters and in a bigger font, I would. When I tell you on the first day of taking it, the bleeding was much lighter, and on the 5th day it was gone. All I took was one tablespoon daily."

1 / 10
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  • you...
  • Taken for 6 months to 1 year
  • December 24, 2014

For Abnormal Uterine Bleeding "I have been receiving the Depo shot since July 2013. This has been my first and only birth control I've taken, and a huge benefit is that I am not worrying about taking a pill. However, for the past 6 months, I have experienced spotting. It is not enough blood to need to wear a tampon, however, it is very dark blood, which stains underwear. This has been extremely frustrating to me, and I am now trying to decide what my next best option for birth control will be."

7 / 10
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  • Anonymous
  • February 3, 2020

For Abnormal Uterine Bleeding "I received my second Depo Provera shot early October after having it once before and while I was 17/18. My mood swings are horrible still, breast tenderness is outrageous. I also have had the worst cramping pain (worse than IUD pain). It was unbearable when I first started ovulating. I could not lay flat in bed, had a heating blanket and heating pad on my lower back and abdominal area for a week. I took Midol and ibuprofen like the doctors told me, and nothing has stopped this. I have clots coming out, they want me to come in again to poke at me. Just super put out and exhausted. I am sleeping up to 10-12 hours a day. It has caused me to have less ambition at my workplace too. I am very active as I am a CNA at the hospital, but I bleed through my pants at least two times a shift. My acne is horrible around my chin, and my stomach is sore from the on and off bloating. It brought tears to my eyes finding this page and seeing I am not alone in this."

1 / 10
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  • Anonymous
  • April 12, 2009

For Birth Control "I had nothing but negative effects from the Depo shot that are continuing even after the duration of action of the Depo. I am now experiencing terrible migraines (I rarely, if ever had even minor headaches). They have been occurring multiple times per day including nausea and diarrhea. I experienced these same symptoms for the first time after I received my first shot. I also experienced neck stiffness, severe mood swings, bouts of depression that seemed to arrive from nowhere, no sex drive whatsoever, and worst of all menstrual bleeding for an entire month straight which was only counteracted by a high dosage of birth control pills."

3 / 10
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  • Ove...
  • Taken for less than 1 month
  • September 21, 2018

For Abnormal Uterine Bleeding "It’s a good medicine overall. I had really heavy bleeding and got sent to the hospital, and they put me on this, which was 10 mg for 20 days, and I stopped bleeding 12 days into it. But after reading some of these comments, it makes me so worried because once I stop it, I’ll have the “breakthrough” bleeding. So my thing is, how are you going to put someone on something for so long, then when they stop taking it, it’ll come rushing again? Hmm."

5 / 10
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  • Lis...
  • Taken for less than 1 month
  • March 9, 2020

For Abnormal Uterine Bleeding "I took Provera for 21 days to treat very heavy nonstop bleeding. I am 45. At first, it drastically reduced my bleeding for a few days, but the bleeding continued quite heavily again until the last 4 days of being on it."

7 / 10
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  • cla...
  • January 10, 2013

For Endometriosis "I got on this as a teenager for my endometriosis. Besides spotting for the first four months, I have had no ill effects. No weight gain. In fact, it's hard to keep weight on. I got off of it to have my kids. Now I'm back on it. It's so much easier raising toddlers without cramps and random bleeding. I recommend it highly. Don't let bad experiences scare you. I actually had a horrible time with the pill. I love my Depo shots!"

10 / 10
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  • Jan...
  • March 14, 2009

For Abnormal Uterine Bleeding "I am a 51-year-old female. In January 2008, I had a light period that lasted for 4 days and then stopped. Five days later, I started bleeding again. I had such a heavy flow with clotting that I had to change every 2 hours. After the 14th day, I began to get very weak. My mother convinced me that this was not normal and to see a gynecologist. On day 16 of this heavy bleeding, I went to the gynecologist. She told me I was going through menopause and prescribed Provera. On the next day, I was to take 20mg for 10 days. After 2 days, I stopped bleeding. On day 12, my doctor told me I needed to do this for the next 3 months and each month would get better, and it would help me through menopause. I do not feel good at all when I take the Provera."

6 / 10
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  • Ms ...
  • Taken for 2 to 5 years
  • November 6, 2013

For Abnormal Uterine Bleeding "When I was first on Depo Provera, I bled for 6 months straight. The OB said my body had to get used to it and I would need another cycle, so I took the shot for another 6 months, and lo and behold, I had bleeding every day for 1 year. I don't even know how that was possible, but it was like a heavy period every day. When I called the OB and other clinics, everyone said, 'You signed a waiver.' OK, well no one said if I had a problem. I stopped Depo, and like a silly college kid, I was convinced to take Depo 6 months later. The OB said my body may be different, and again I had my period for 6 more months. Thank goodness there were no effects except the annoyance of bleeding every day for 18 months altogether. This shot does work, why have sex bleeding?"

4 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.