Tri-Estarylla Dosage
Generic name: NORGESTIMATE 0.180mg, ETHINYL ESTRADIOL 0.035mg; NORGESTIMATE 0.215mg, ETHINYL ESTRADIOL 0.035mg; NORGESTIMATE 0.25mg, ETHINYL ESTRADIOL 0.035mg;
Dosage form: tablets
Drug class: Contraceptives
Medically reviewed by Drugs.com. Last updated on Aug 1, 2023.
Recommended Dosage and Administration
Take one tablet by mouth at the same time each day with or without food. Table 1 provides the recommended dosage and administration instructions for Tri-Estarylla.
Table 1: Instructions for Administration of Tri-Estarylla |
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Starting COCs in women not currently using hormonal contraception (Day 1 Start or Sunday Start)
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Day 1 Start:
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Sunday Start:
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Switching to Tri-Estarylla from another oral contraceptive |
Start on the same day that a new pack of the previous oral contraceptive would have started. |
Switching from another contraceptive method to Tri-Estarylla |
Start Tri-Estarylla |
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Complete instructions to facilitate patient counseling on proper tablet usage are located in the FDA-Approved Patient Labeling. |
Starting Tri-Estarylla after Abortion or Miscarriage
First-trimester
- After a first-trimester abortion or miscarriage, Tri-Estarylla may be started immediately. An additional method of contraception is not needed if Tri-Estarylla is started immediately.
- If Tri-Estarylla is not started within 5 days after termination of the pregnancy, the patient should use additional non-hormonal contraception (such as condoms and spermicide) for the first seven days of her first cycle blister pack of Tri-Estarylla.
Second-trimester
- Do not start until 4 weeks after a second-trimester abortion or miscarriage, due to the increased risk of thromboembolic disease. Start Tri-Estarylla, following the instructions in Table 1 for Day 1 or Sunday start, as desired. If using Sunday start, use additional non-hormonal contraception (such as condoms and spermicide) for the first seven days of the patient's first cycle pack of Tri-Estarylla. [see CONTRAINDICATIONS (4), WARNINGS and PRECAUTIONS (5.1), and FDA-APPROVED PATIENT LABELING].
Starting Tri-Estarylla after Childbirth
- Do not start until 4 weeks after delivery, due to the increased risk of thromboembolic disease. Start contraceptive therapy with Tri-Estarylla following the instructions in Table 1 for women not currently using hormonal contraception.
- Tri-Estarylla are not recommended for use in lactating women [SEE USE IN SPECIFIC POPULATIONS (8.2)].
- If the woman has not yet had a period postpartum, consider the possibility of ovulation and conception occurring prior to use of Tri-Estarylla. [see CONTRAINDICATIONS (4), WARNINGS AND PRECAUTIONS (5.1), AND USE IN SPECIFIC POPULATIONS (8.1) AND (8.2)].
Recommendations Regarding Missed Doses
Contraceptive failure may occur when active tablets are missed. Table 2 describes instructions for Tri-Estarylla dosing and use of additional non-hormonal contraception (such as condoms) when active tablets are missed.
Table 2: Instructions for Missed Tri-Estarylla Tablets |
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Take the tablet as soon as possible. Continue taking one tablet a day until the pack is finished. |
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Take the two missed tablets as soon as possible and the next two active tablets the next day. Continue taking one tablet a day until the pack is finished. Additional non-hormonal contraception (such as condoms and spermicide) should be used as back-up if the patient has sex within 7 days after missing tablets. |
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Day 1 start: Throw out the rest of the pack and start a new pack that same day. |
Dosage Recommendations if Vomiting or Diarrhea Occurs
In case of severe vomiting or diarrhea, absorption may not be complete and additional contraceptive measures should be taken. If vomiting or diarrhea occurs within 3 to 4 hours after taking an active tablet, handle this as a missed tablet.
Tri-Estarylla Use for Acne
The timing of initiation of dosing with Tri-Estarylla for acne should follow the guidelines for use of Tri-Estarylla as an oral contraceptive. Consult the DOSAGE AND ADMINISTRATION section (2.1) for instructions.
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