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Medications for Pulmonary Hypertension

Drugs associated with Pulmonary Hypertension

The following drugs and medications are in some way related to, or used in the treatment of this condition.

What is Pulmonary Hypertension: Pulmonary hypertension is usually caused by a narrowing of the small arteries of the lung, which makes it hard for blood to flow. Blood pressure increases. The right side of the heart must work harder to pump blood, and may become enlarged over time. Eventually, heart failure may develop.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
Revatio Rx B N X 6 reviews
7.0

Generic name: sildenafil systemic

Drug class: agents for pulmonary hypertension

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Tracleer Rx X N 2 reviews
7.0

Generic name: bosentan systemic

Drug class: agents for pulmonary hypertension

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Letairis Rx X N 9 reviews
8.0

Generic name: ambrisentan systemic

Drug class: agents for pulmonary hypertension

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
sildenafil Rx B N X 6 reviews
7.0

Generic name: sildenafil systemic

Brand name:  Revatio

Drug class: impotence agents, agents for pulmonary hypertension

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Adcirca Rx B N X 5 reviews
5.0

Generic name: tadalafil systemic

Drug class: agents for pulmonary hypertension

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
isosorbide dinitrate Off Label Rx C N Add review Add

Generic name: isosorbide dinitrate systemic

Brand names:  Isordil, Isordil Titradose, Dilatrate-SR, Isochron, IsoDitrate

Drug class: antianginal agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

Off Label: Yes

 
Remodulin Rx B N Add review
4.0

Generic name: treprostinil systemic

Drug class: agents for pulmonary hypertension

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Tyvaso Rx B N 6 reviews
8.0

Generic name: treprostinil systemic

Drug class: agents for pulmonary hypertension

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Flolan Rx B N 2 reviews
8.0

Generic name: epoprostenol systemic

Drug class: agents for pulmonary hypertension

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Isordil Off Label Rx C N Add review Add

Generic name: isosorbide dinitrate systemic

Drug class: antianginal agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
Ventavis Rx C N Add review
8.0

Generic name: iloprost systemic

Drug class: agents for pulmonary hypertension

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
bosentan Rx X N 2 reviews
7.0

Generic name: bosentan systemic

Brand name:  Tracleer

Drug class: agents for pulmonary hypertension

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
ambrisentan Rx X N 10 reviews
8.0

Generic name: ambrisentan systemic

Brand name:  Letairis

Drug class: agents for pulmonary hypertension

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
tadalafil Rx B N X 5 reviews
6.0

Generic name: tadalafil systemic

Brand name:  Adcirca

Drug class: impotence agents, agents for pulmonary hypertension

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
Veletri Rx B N Add review Add

Generic name: epoprostenol systemic

Drug class: agents for pulmonary hypertension

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Orenitram Rx B N Add review Add

Generic name: treprostinil systemic

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Isordil Titradose Off Label Rx C N Add review Add

Generic name: isosorbide dinitrate systemic

Drug class: antianginal agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
Dilatrate-SR Off Label Rx C N Add review Add

Generic name: isosorbide dinitrate systemic

Drug class: antianginal agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
epoprostenol Rx B N 2 reviews
8.0

Generic name: epoprostenol systemic

Brand names:  Flolan, Veletri

Drug class: agents for pulmonary hypertension

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
treprostinil Rx B N 6 reviews
7.0

Generic name: treprostinil systemic

Brand names:  Remodulin, Tyvaso, Orenitram

Drug class: agents for pulmonary hypertension

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
Isochron Off Label Rx C N Add review Add

Generic name: isosorbide dinitrate systemic

Drug class: antianginal agents

For consumers: dosage, interactions, side effects

Off Label: Yes

 
IsoDitrate Off Label Rx C N Add review Add

Generic name: isosorbide dinitrate systemic

Drug class: antianginal agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off Label: Yes

 
iloprost Rx C N Add review
8.0

Generic name: iloprost systemic

Brand name:  Ventavis

Drug class: agents for pulmonary hypertension

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
Opsumit Rx X N 1 review
10

Generic name: macitentan systemic

Drug class: agents for pulmonary hypertension

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Adempas Rx X N Add review Add

Generic name: riociguat systemic

Drug class: vasodilators

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph

 
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Learn more about Pulmonary Hypertension

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N The drug is not subject to the Controlled Substances Act.
1 The drug has a high potential for abuse. The drug has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use of the drug under medical supervision.
2 The drug has a high potential for abuse. The drug has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse of the drug may lead to severe psychological or physical dependence.
3 The drug has a potential for abuse less than the drugs in schedules 1 and 2. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to moderate or low physical dependence or high psychological dependence.
4 The drug has a low potential for abuse relative to the drugs in schedule 3. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to limited physical dependence or psychological dependence relative to the drugs in schedule 3.
5 The drug has a low potential for abuse relative to the drugs in schedule 4. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to limited physical dependence or psychological dependence relative to the drugs in schedule 4.
Alcohol
X Interacts with Alcohol.

Synonym(s): PAH; Pulmonary Arterial Hypertension

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