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Letairis (ambrisentan) Drug Interactions

A total of 130 drugs are known to interact with Letairis (ambrisentan).

  • 5 major drug interactions
  • 86 moderate drug interactions
  • 39 minor drug interactions

Show all medications in the database that may interact with Letairis (ambrisentan).

Check for interactions with Letairis (ambrisentan)

Type in a drug name and select a drug from the list.

Common medications checked in combination with Letairis (ambrisentan)

  • Adcirca (tadalafil)
  • Adempas (riociguat)
  • Advair Diskus (fluticasone / salmeterol)
  • aspirin (Aspir 81, Ecotrin, Acetylsalicylic Acid, Aspirin Low Strength, Bayer Aspirin, Aspir-Low, Ascriptin, Arthritis Pain, Fasprin, Ecotrin Adult Low Strength, Low Dose ASA, Bufferin, Aspiritab, Aspirin Lite Coat, Easprin, Bayer Children's Aspirin, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Bayer Aspirin Regimen, Aspirtab, Halfprin, Aspergum, Durlaza, Acuprin 81, Miniprin, Bufferin Low Dose, Empirin, Buffered Aspirin, Entercote, St. Joseph Aspirin, Ascriptin Enteric, Ecpirin, Bayer Women's Aspirin With Calcium, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Aspi-Cor, Medi-Seltzer, Sloprin, St. Joseph 81 mg Chewable Aspirin, ZORprin, Bayer Aspirin Extra Strength Plus, Buffex, Ecotrin Maximum Strength, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Bufferin Extra Strength, Therapy Bayer, Stanback Analgesic, Norwich Aspirin, Zero-Order Release, YSP Aspirin, Migralex, Heartline, Bayer Advanced Aspirin, Buffasal)
  • carvedilol (Coreg, Coreg CR)
  • furosemide (Lasix, Diaqua-2, Lo-Aqua)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • Lasix (furosemide)
  • levothyroxine (Synthroid, Levoxyl, Tirosint, Levothroid, Eltroxin, Levothyrox, Unithroid, Euthyrox, Levo-T, L Thyroxine Roche, Novothyrox, Levotabs, Oroxine, Eutroxsig, Tirosint-Sol, Levotec, Evotrox)
  • Lyrica (pregabalin)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • oxygen
  • potassium chloride (Klor-Con, KCl, K-Dur, Klor-Con M20, K-Tab, Klor-Con M10, Klor-Con 10, Micro-K, Slow-K, Kay Ciel, K-Dur 20, K-Lor, Klor-Con Sprinkle, Klotrix, Micro-K 10, K-Dur 10, Ten-K, Epiklor, Kaochlor, Kaon-CI, K-Norm, Kal Potassium 99, Kaochlor S-F, Cena K, Kaon-CL 20%, K-Sol, K + Potassium, Klor-Con/25, K-8, Klor-Con 8, K-10, Glu-K, Kaon-CL 10, Kato, Ed K+10, PC-10, Klor-Con M15, K-Vescent (Potassium Chloride), K+Care, Klorvess, Rum-K, Gen-K)
  • prednisone (Deltasone, Rayos, Sterapred DS, Sterapred, Prednicot, Meticorten, Liquid Pred, Orasone, Prednicen-M)
  • Revatio (sildenafil)
  • sildenafil (Viagra, Revatio)
  • spironolactone (Aldactone, CaroSpir)
  • tadalafil (Cialis, Adcirca)
  • Tracleer (bosentan)
  • trazodone (Desyrel, Oleptro, Desyrel Dividose)
  • Viagra (sildenafil)
  • Vitamin B12 (cyanocobalamin)
  • Vitamin D3 (cholecalciferol)
  • warfarin (Coumadin, Jantoven)

Letairis (ambrisentan) disease Interactions

There are 4 disease interactions with Letairis (ambrisentan) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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