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Macitentan Dosage

Medically reviewed by Last updated on Oct 30, 2023.

Applies to the following strengths: 10 mg

Usual Adult Dose for Pulmonary Hypertension

10 mg orally once a day

Uses: For the treatment of pulmonary arterial hypertension (PAH, WHO Group I) to delay disease progression

Renal Dose Adjustments

No adjustment recommended.

Liver Dose Adjustments

No adjustment recommended.

If hepatic dysfunction develops during treatment:


The US FDA requires a Risk Evaluation and Mitigation Strategy (REMS) for macitentan. It includes elements to assure safe use and an implementation system. For additional information:


This drug is not recommended for use in children.

Consult WARNINGS section for additional precautions.


No adjustment recommended.

Other Comments

Administration advice:


Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.