Opsumit (macitentan) Drug Interactions
A total of 154 drugs (579 brand and generic names) are known to interact with Opsumit (macitentan).
- 60 major drug interactions (198 brand and generic names)
- 91 moderate drug interactions (373 brand and generic names)
- 3 minor drug interactions (8 brand and generic names)
Check for interactions with Opsumit (macitentan)
Common medications checked in combination with Opsumit (macitentan)
- Adcirca (tadalafil)
- Adempas (riociguat)
- alprazolam
- aspirin
- atorvastatin
- digoxin
- furosemide
- hydroxychloroquine
- Lasix (furosemide)
- Letairis (ambrisentan)
- lisinopril
- metformin
- metolazone
- omeprazole
- sildenafil
- spironolactone
- Tyvaso (treprostinil)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Xarelto (rivaroxaban)
See also...
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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