Iloprost Side Effects
Commonly reported side effects of iloprost include: trismus, increased cough, vasodilatation, and flushing. Other side effects include: glossalgia, and insomnia. See below for a comprehensive list of adverse effects.
For the Consumer
Applies to iloprost: inhalation solution
In addition to its needed effects, some unwanted effects may be caused by iloprost. In the event that any of these side effects do occur, they may require medical attention.
Major Side Effects
You should check with your doctor immediately if any of these side effects occur when taking iloprost:Incidence not known:
- Black, tarry stools
- chest pain
- difficult or labored breathing
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- extreme fatigue
- fast, pounding, or irregular heartbeat or pulse
- hives or rash
- irregular breathing
- noisy breathing
- pinpoint red spots on the skin
- swelling of the eyelids, face, lips, fingers, feet, or lower legs
- tightness in the chest
- troubled breathing or swallowing
- unusual bleeding or bruising
Minor Side Effects
Some of the side effects that can occur with iloprost may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:More common:
- Back pain
- cough increased
- coughing or spitting up blood
- difficulty opening the mouth
- feeling of warmth
- redness of the face, neck, arms, and occasionally, upper chest
- trouble sleeping
- Change in taste
- mouth irritation
- tongue irritation or pain
- stuffy nose
For Healthcare Professionals
Applies to iloprost: inhalation solution
Cardiovascular side effects have included congestive heart failure, chest pain, supraventricular tachycardia, peripheral edema, vasodilation (flushing), hypotension, palpitations and syncope.[Ref]
Gastrointestinal side effects have included nausea and vomiting. Postmarketing experience has included diarrhea.[Ref]
Hepatic side effects have included increased GGT (gamma-glutamyltranspeptidase) and alkaline phosphatase levels.[Ref]
Musculoskeletal side effects have included muscle cramps, back pain, tongue pain and trismus.[Ref]
Nervous system side effects have included headache, dizziness and insomnia.[Ref]
Renal side effects have included kidney failure.[Ref]
Respiratory side effects have included hemoptysis, pneumonia, dyspnea and increased cough. Postmarketing experience has included cases of bronchospasm and wheezing, particularly in susceptible patients with hyperreactive airways.[Ref]
General side effects have included flu syndrome. Postmarketing reports have included mouth and tongue irritation and dysgeusia.[Ref]
Other side effects have included cases of epistaxis and gingival bleeding which have been reported within one month of starting iloprost treatment.[Ref]
Hypersensitivity side effects have included postmarketing reports of hypersensitivity and rash.
Dermatologic side effects have included postmarketing reports of rash.
Hematologic side effects have included postmarketing reports of thrombocytopenia.
1. "Product Information. Ventavis (iloprost)." CoTherix Inc, South San Francisco, CA.
Not all side effects for iloprost may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
More about iloprost
- Other brands: Ventavis
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