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Generic name: tadalafilta-DAL-a-fil ]
Brand names: Adcirca, Alyq, Cialis, Tadalafil (Eqv-Adcirca), Tadalafil (Eqv-Cialis), Tadliq
Drug class: Agents for pulmonary hypertension

Medically reviewed by on Dec 11, 2023. Written by Cerner Multum.

What is Alyq?

Alyq is used in adult men to treat erectile dysfunction (impotence) and symptoms of benign prostatic hypertrophy (enlarged prostate).

Alyq can also be used in men and women to treat pulmonary arterial hypertension (PAH) and improve exercise capacity.

Do not take Alyq for erectile dysfunction and symptoms of enlarged prostate if you are taking this medicine for pulmonary arterial hypertension.

Alyq may also be used for purposes not listed in this medication guide.

Alyq side effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Alyq may cause serious side effects. Stop using Alyq and call your doctor at once if you have:

Get emergency medical help if you have nausea, chest pain, dizziness during sex.

Common side effects of Alyq may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Some drugs can cause unwanted or dangerous effects when used with Alyq. Tell your doctor about all your other medicines.

Stop using Alyq and get emergency medical help if you have sudden vision loss or hearing problems.

Get emergency medical help at once if you have nausea, chest pain, or dizziness during sex.

Before taking this medicine

You should not take Alyq if you are allergic to it, or if you take other medicines to treat pulmonary arterial hypertension, such as riociguat (Adempas).

Do not take Alyq if you are also using certain medicines for chest pain or heart problems called nitrates. These include nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Nitrates are also found in some recreational drugs such as amyl nitrate, butyl nitrate or nitrite ("poppers"). Taking this medicine with a nitrate can cause a sudden and serious decrease in blood pressure.

Some Alyq can remain in your bloodstream for 2 or more days after each dose you take (longer if you have liver or kidney disease). Avoid nitrate use during this time.

Tell your doctor if you have or have ever had:

It is not known if Alyq will harm an unborn baby. However, having pulmonary hypertension during pregnancy may cause complications or medical problems such as heart failure, and stroke in both mother and baby. Tell your doctor if you are pregnant or plan to become pregnant.

Ask a doctor if it is safe to breastfeed while using Alyq.

Not approved for use by anyone younger than 18 years old.

How should I take Alyq?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Your dose needs may change if you switch to a different brand, strength, or form of this medicine. Avoid medication errors by using exactly as directed on the label, or as prescribed by your doctor.

When taking Alyq for erectile dysfunction, take it when needed, about 30 minutes before sexual activity. The medicine can help achieve an erection when sexual stimulation occurs. An erection will not occur just by taking a pill.

If you take Alyq once a day, take it at the same time each day, with or without food.

Swallow the tablet whole and do not crush, chew, or break it.

Shake the oral suspension (liquid) for 30 seconds before you measure a dose. Measure a dose with the supplied measuring device (not a kitchen spoon).

Do not use this medication more than once per day.

Do not change your Alyq dose or stop taking this medicine. Follow your doctor's dosing instructions very carefully.

If you receive medical care for heart problems, tell your caregivers when you last took Alyq.

This medicine does not prevent the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV).

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Alyq?

Avoid drinking alcohol. Alcohol can further lower your blood pressure and may increase your risk of headache, dizziness, or fainting.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

Grapefruit may interact with Alyq and cause side effects. Avoid consuming grapefruit products.

What other drugs will affect Alyq?

Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective.

Tell your doctor about all your other medicines, especially:

This list is not complete and many other drugs may affect Alyq. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Frequently asked questions

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.