Adempas Side Effects
Generic Name: riociguat
Note: This page contains information about the side effects of riociguat. Some of the dosage forms included on this document may not apply to the brand name Adempas.
Common side effects of Adempas include: dyspepsia, gastritis, and headache. See below for a comprehensive list of adverse effects.
For the Consumer
Applies to riociguat: oral tablet
In addition to its needed effects, some unwanted effects may be caused by riociguat (the active ingredient contained in Adempas). In the event that any of these side effects do occur, they may require medical attention.
Major Side Effects
You should check with your doctor immediately if any of these side effects occur when taking riociguat:More common:
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- unusual tiredness or weakness
- Abdominal or stomach pain or swelling
- bloating or swelling of the face, arms, hands, lower legs, or feet
- bloody or black, tarry stools
- bruising or purple areas on the skin
- coughing or spitting up blood
- decreased alertness
- fast, irregular, pounding, or racing heartbeat or pulse
- heavy non-menstrual vaginal bleeding
- rapid weight gain
- troubled breathing with exertion
- vomiting of blood or material that looks like coffee grounds
Minor Side Effects
Some of the side effects that can occur with riociguat may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:More common:
- heartburn or indigestion
- nausea or vomiting
- stuffy nose
- Difficulty having a bowel movement (stool)
For Healthcare Professionals
Applies to riociguat: oral tablet
Very common (10% or more): Hypotension (10%)
Frequency not reported: Palpitations, peripheral edema[Ref]
Very common (10% or more): Dyspepsia (21%), gastritis (21%), nausea (14%), diarrhea (12%), vomiting (10%)
Common (1% to 10%): Gastroesophageal reflux disease, constipation
Frequency not reported: Dysphagia, abdominal distention[Ref]
Common (1% to 10%): Anemia[Ref]
Very common (10% or more): Headache (27%), dizziness (20%)[Ref]
Frequency not reported: Nasal congestion, epistaxis[Ref]
1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
2. "Product Information. Adempas (riociguat)." Bayer Pharmaceutical Inc, West Haven, CT.
Not all side effects for Adempas may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
More about Adempas (riociguat)
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