Clonidine Alternatives Compared
| Clonidine | Botox | Qulipta |
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| Clonidine | Botox (onabotulinumtoxinA) | Qulipta (atogepant) |
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Prescription only
Clonidine can be used to lower blood pressure and treat ADHD; however, it causes sedation, and tolerance can develop to its blood pressure-lowering effects. Clonidine should not be stopped suddenly... View more |
Prescription only
Botox is approved to treat many conditions, such as chronic migraine, involuntary muscle contractions or twitching, excessive sweating, increased saliva, and overactive bladder to name a few. Botox... View more |
Prescription only
Prescribed for Chronic Migraine, Migraine Prevention. Qulipta may also be used for purposes not listed in this medication guide. |
Related suggestions Migraine Prevention (Migraine Prophylaxis)
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| More about Clonidine | More about Botox (onabotulinumtoxinA) | More about Qulipta (atogepant) | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
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No lower-cost generic available |
No lower-cost generic available |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Clonidine has an average rating of 7.2 out of 10 from a total of 743 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 21% reported a negative effect. |
Botox has an average rating of 5.5 out of 10 from a total of 457 ratings on Drugs.com. 45% of reviewers reported a positive effect, while 43% reported a negative effect. |
Qulipta has an average rating of 7.3 out of 10 from a total of 84 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 16% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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Commonly reported side effects include:
See also: clonidine side effects in more detail. |
Common side effects include:
See also: Botox side effects in more detail. |
See also: Qulipta side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all clonidine prices |
View all Botox prices |
View all Qulipta prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Catapres, Catapres-TTS, Clonidine ER, Duraclon, Kapvay, Nexiclon XR | Other onabotulinumtoxinA brands include: Botox Cosmetic |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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15 hours |
N/A |
11 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 367 drugs are known to interact with clonidine:
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A total of 114 drugs are known to interact with Botox:
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A total of 172 drugs are known to interact with Qulipta:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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September 03, 1974 |
December 09, 1991 |
September 28, 2021 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.