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Medications for Tardive Dyskinesia

About Tardive Dyskinesia

Tardive dyskinesia are involuntary movements, especially of the lower face, that develop after exposure to a group of medications known as neuroleptics. The abnormal movements include tongue thrusting, repetitive chewing, jaw swinging and/or facial grimacing.

The most commonly used offending neuroleptics are typical (old generation) antipsychotic medications, such as haloperidol, trifluoperazine, or fluphenazine. They act by blocking dopamine receptors in the brain.

The condition may be reversible, if recognized in the earliest stages, by stopping the causative agent, but may be permanent. On occasion, if the anti-psychotics are stopped after the tardive dyskinesia has been present for a long period, the condition may become significantly worse.

Drugs used to treat Tardive Dyskinesia

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Ingrezza 3.3 4 reviews
Rx N X

Generic name: valbenazine systemic

Drug class: VMAT2 inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

propranolol Off-label Rate Add review
Rx C N X

Generic name: propranolol systemic

Drug class: non-cardioselective beta blockers, group II antiarrhythmics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

Austedo 5.5 2 reviews
Rx N X

Generic name: deutetrabenazine systemic

Drug class: VMAT2 inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

valbenazine 4.4 5 reviews
Rx N X

Generic name: valbenazine systemic

Brand name:  Ingrezza

Drug class: VMAT2 inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

vitamin e 1.0 1 review
Rx/OTC C N

Generic name: vitamin e systemic

Brand names:  Aquasol E, Aquavite-E, Alpha E, E-600, Aqua-E, Aqua Gem-E, E-400 Clear, E-Gems, E Pherol …show all

Drug class: vitamins

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Natural Product Monographs

deutetrabenazine 3.3 4 reviews
Rx N X

Generic name: deutetrabenazine systemic

Brand name:  Austedo

Drug class: VMAT2 inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

apomorphine Off-label Rate Add review
Rx C N X

Generic name: apomorphine systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Off-label: Yes

tetrabenazine Off-label 0.0 1 review
Rx C N X

Generic name: tetrabenazine systemic

Drug class: VMAT2 inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

clonidine Off-label Rate Add review
Rx C N X

Generic name: clonidine systemic

Drug class: antiadrenergic agents, centrally acting

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

ropinirole Off-label Rate Add review
Rx C N X

Generic name: ropinirole systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

pramipexole Off-label Rate Add review
Rx C N X

Generic name: pramipexole systemic

Drug class: dopaminergic antiparkinsonism agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

chlordiazepoxide Off-label Rate Add review
Rx N 4 X

Generic name: chlordiazepoxide systemic

Drug class: benzodiazepines

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

bromocriptine Off-label Rate Add review
Rx B N X

Generic name: bromocriptine systemic

Drug class: dopaminergic antiparkinsonism agents, prolactin inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

Aquasol E Rate Add review
Rx/OTC C N

Generic name: vitamin e systemic

Drug class: vitamins

For consumers: dosage, interactions, side effects

Aquavite-E 1.0 1 review
Rx/OTC C N

Generic name: vitamin e systemic

Drug class: vitamins

For consumers: dosage, interactions, side effects

Alpha E Rate Add review
Rx/OTC C N

Generic name: vitamin e systemic

Drug class: vitamins

For consumers: dosage, interactions, side effects

E-600 Rate Add review
Rx/OTC C N

Generic name: vitamin e systemic

Drug class: vitamins

For consumers: dosage, interactions, side effects

Aqua-E Rate Add review
Rx/OTC C N

Generic name: vitamin e systemic

Drug class: vitamins

For consumers: dosage, interactions, side effects

Aqua Gem-E Rate Add review
Rx/OTC C N

Generic name: vitamin e systemic

Drug class: vitamins

For consumers: dosage, interactions, side effects

E-400 Clear Rate Add review
Rx/OTC C N

Generic name: vitamin e systemic

Drug class: vitamins

For consumers: dosage, interactions, side effects

E-Gems Rate Add review
Rx/OTC C N

Generic name: vitamin e systemic

Drug class: vitamins

For consumers: dosage, interactions, side effects

E Pherol Rate Add review
Rx/OTC C N

Generic name: vitamin e systemic

Drug class: vitamins

For consumers: dosage, interactions, side effects

Learn more about Tardive Dyskinesia

IBM Watson Micromedex

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription Only.
OTC Over the Counter.
Rx/OTC Prescription or Over the Counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

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