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Valbenazine Side Effects

In Summary

Commonly reported side effects of valbenazine include: drowsiness, fatigue, and sedation. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to valbenazine: oral capsule

Along with its needed effects, valbenazine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking valbenazine:

Less common
  • Dizziness
  • inability to sit still
  • need to keep moving
  • restlessness
  • trouble walking
Incidence not known
  • Fainting
  • irregular heartbeat recurrent

Some side effects of valbenazine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Blurred vision
  • decrease in the frequency of urination
  • decrease in urine volume
  • difficulty having a bowel movement (stool)
  • difficulty in passing urine (dribbling)
  • dry mouth
  • painful urination
  • sleepiness or unusual drowsiness
Less common

For Healthcare Professionals

Applies to valbenazine: oral capsule


-The most common adverse reaction (5% or more and twice the rate of placebo) was somnolence.
-A total of 3% of patients discontinued treatment because of adverse reactions.[Ref]

Nervous system

Very common (10% or more): Somnolence/fatigue/sedation (10.9%)
Common (1% to 10%): Anticholinergic effects (dry mouth, constipation, attention disturbance, blurred vision, urinary retention), balance disorders/fall/gait disturbance/dizziness, headache, akathisia/restlessness, drooling, dyskinesia,
non-akathisia extrapyramidal symptoms[Ref]


Common (1% to 10%): Vomiting, nausea[Ref]


Common (1% to 10%): Increased alkaline phosphatase and bilirubin[Ref]


Common (1% to 10%): Increased blood glucose, increased weight, increased prolactin[Ref]


Common (1% to 10%): Arthralgia[Ref]


Common (1% to 10%): Anxiety, insomnia[Ref]


Common (1% to 10%): Respiratory infections[Ref]


1. "Product Information. Ingrezza (valbenazine)." Neurocrine Biosciences, Inc., San Diego, CA.

Some side effects of valbenazine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.