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Deutetrabenazine Dosage

Medically reviewed by Last updated on Jul 11, 2023.

Applies to the following strengths: 6 mg; 9 mg; 12 mg; 24 mg; 6 mg-12 mg-24 mg

Usual Adult Dose for Huntington Disease


Use: For chorea associated with Huntington's disease

Usual Adult Dose for Tardive Dyskinesia


Use: For tardive dyskinesia

Renal Dose Adjustments

Data not available

Liver Dose Adjustments


Dose Adjustments

Patients switching from tetrabenazine to deutetrabenazine: Discontinue tetrabenazine and initiate deutetrabenazine the following day; the initial dose for deutetrabenazine is based on the current tetrabenazine daily dose (TDD):

CYP450 2D6 Poor Metabolizers OR Concomitant Use of Strong CYP450 2D6 Inhibitors:


DEPRESSION/SUICIDALITY: This drug can increase the risk of depression and suicidality (suicidal thoughts and behavior) in patients with Huntington's disease; therefore, it is contraindicated in patients with untreated or inadequately treated depression and in those who are suicidal.


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments

Administration Advice:

Storage Requirements:


Patient Advice:

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.