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Ingrezza Side Effects

Generic name: valbenazine

Medically reviewed by Last updated on Mar 15, 2022.

Note: This document contains side effect information about valbenazine. Some of the dosage forms listed on this page may not apply to the brand name Ingrezza.

In Summary

Common side effects of Ingrezza include: drowsiness, fatigue, and sedated state. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to valbenazine: oral capsule

Side effects requiring immediate medical attention

Along with its needed effects, valbenazine (the active ingredient contained in Ingrezza) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking valbenazine:

Less common

  • Absence of or decrease in body movement
  • clumsiness or unsteadiness
  • dizziness
  • drooling
  • inability to sit still
  • loss of balance control
  • need to keep moving
  • restlessness
  • trembling and shaking of the fingers or hands
  • trouble walking

Incidence not known

Side effects not requiring immediate medical attention

Some side effects of valbenazine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Blurred vision
  • decrease in the frequency of urination
  • decrease in urine volume
  • difficulty having a bowel movement (stool)
  • difficulty in passing urine (dribbling)
  • dry mouth
  • painful urination
  • sleepiness or unusual drowsiness

Less common

For Healthcare Professionals

Applies to valbenazine: oral capsule


-The most common adverse reaction (5% or more and twice the rate of placebo) was somnolence.

-A total of 3% of patients discontinued treatment because of adverse reactions.[Ref]

Nervous system

Very common (10% or more): Somnolence/fatigue/sedation (10.9%)

Common (1% to 10%): Anticholinergic effects (dry mouth, constipation, attention disturbance, blurred vision, urinary retention), balance disorders/fall/gait disturbance/dizziness, headache, akathisia/restlessness, drooling, dyskinesia,

non-akathisia extrapyramidal symptoms[Ref]


Common (1% to 10%): Vomiting, nausea[Ref]


Common (1% to 10%): Increased alkaline phosphatase and bilirubin[Ref]


Common (1% to 10%): Increased blood glucose, increased weight, increased prolactin[Ref]


Common (1% to 10%): Arthralgia[Ref]


Common (1% to 10%): Anxiety, insomnia[Ref]


Common (1% to 10%): Respiratory infections[Ref]

Frequently asked questions


1. "Product Information. Ingrezza (valbenazine)." Neurocrine Biosciences, Inc., San Diego, CA.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.