Skip to main content

Ingrezza Side Effects

Generic name: valbenazine

Medically reviewed by Philip Thornton, DipPharm. Last updated on May 25, 2023.

Note: This document contains side effect information about valbenazine. Some dosage forms listed on this page may not apply to the brand name Ingrezza.


Common side effects of Ingrezza include: drowsiness, fatigue, and sedated state. Continue reading for a comprehensive list of adverse effects.

Applies to valbenazine: oral capsules.

Side effects include:

Adverse effects occurring in ≥2% of patients receiving valbenazine (the active ingredient contained in Ingrezza) in short-term tardive dyskinesia clinical trials and at a higher frequency than reported with placebo include somnolence (including fatigue and sedation), anticholinergic effects (including dry mouth, constipation, attention disturbance, blurred vision, and urinary retention), balance disorders (including falls, gait disturbances, and dizziness), headache, akathisia/restlessness, vomiting, nausea, and arthralgia.

For Healthcare Professionals

Applies to valbenazine: oral capsule.


-The most common adverse reaction (5% or more and twice the rate of placebo) was somnolence.

-A total of 3% of patients discontinued treatment because of adverse reactions.[Ref]

Nervous system

Very common (10% or more): Somnolence/fatigue/sedation (10.9%)

Common (1% to 10%): Anticholinergic effects (dry mouth, constipation, attention disturbance, blurred vision, urinary retention), balance disorders/fall/gait disturbance/dizziness, headache, akathisia/restlessness, drooling, dyskinesia,

non-akathisia extrapyramidal symptoms[Ref]


Common (1% to 10%): Vomiting, nausea[Ref]


Common (1% to 10%): Increased alkaline phosphatase and bilirubin[Ref]


Common (1% to 10%): Increased blood glucose, increased weight, increased prolactin[Ref]


Common (1% to 10%): Arthralgia[Ref]


Common (1% to 10%): Anxiety, insomnia[Ref]


Common (1% to 10%): Respiratory infections[Ref]

Frequently asked questions


1. Product Information. Ingrezza (valbenazine). Neurocrine Biosciences, Inc. 2017.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.