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Medications for Borderline Personality Disorder

Other names: BPD; EID; EIRD; Emotion-Impulse Regulation Disorder; Emotional Dysregulation Disorder; Emotional Intensity Disorder; Emotional Regulation Disorder; Emotionally Unstable Personality Disorder; ERD; EUPD; Impulsive Personality Disorder; IPD; Personality Disorder, Borderline

Borderline personality disorder (BPD) is a serious mental illness characterized by pervasive instability in moods, interpersonal relationships, self-image, and behavior.

Drugs used to treat Borderline Personality Disorder

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
lorazepam Off-label 9.3 3 reviews
Rx D 4 X

Generic name: lorazepam systemic

Drug class: benzodiazepines, miscellaneous antiemetics, benzodiazepine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

bupropion Off-label 9.0 1 review
Rx C N X

Generic name: bupropion systemic

Drug class: miscellaneous antidepressants, smoking cessation agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

l-methylfolate Off-label 9.0 2 reviews
Rx N N

Generic name: l-methylfolate systemic

Drug class: vitamins

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts

Off-label: Yes

clonazepam Off-label 8.8 5 reviews
Rx D 4 X

Generic name: clonazepam systemic

Drug class: benzodiazepines, benzodiazepine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

escitalopram Off-label 8.6 19 reviews
Rx C N X

Generic name: escitalopram systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

fluoxetine Off-label 8.4 14 reviews
Rx C N X

Generic name: fluoxetine systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

lurasidone Off-label 8.4 15 reviews
Rx B N X

Generic name: lurasidone systemic

Drug class: atypical antipsychotics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

clozapine Off-label 8.2 5 reviews
Rx B N X

Generic name: clozapine systemic

Drug class: atypical antipsychotics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

asenapine Off-label 8.0 2 reviews
Rx C N X

Generic name: asenapine systemic

Drug class: atypical antipsychotics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

citalopram Off-label 7.8 8 reviews
Rx C N X

Generic name: citalopram systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

lamotrigine Off-label 7.6 59 reviews
Rx C N X

Generic name: lamotrigine systemic

Drug class: triazine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

oxcarbazepine Off-label 7.5 6 reviews
Rx C N X

Generic name: oxcarbazepine systemic

Drug class: dibenzazepine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

quetiapine Off-label 7.4 112 reviews
Rx C N X

Generic name: quetiapine systemic

Drug class: atypical antipsychotics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

diazepam Off-label 7.3 8 reviews
Rx D 4 X

Generic name: diazepam systemic

Drug class: benzodiazepines, benzodiazepine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

olanzapine Off-label 7.3 29 reviews
Rx C N X

Generic name: olanzapine systemic

Drug class: atypical antipsychotics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

aripiprazole Off-label 7.2 30 reviews
Rx C N X

Generic name: aripiprazole systemic

Drug class: atypical antipsychotics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

topiramate Off-label 6.9 15 reviews
Rx D N X

Generic name: topiramate systemic

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

sertraline Off-label 6.7 28 reviews
Rx C N X

Generic name: sertraline systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

buspirone Off-label 6.4 12 reviews
Rx B N X

Generic name: buspirone systemic

Drug class: miscellaneous anxiolytics, sedatives and hypnotics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

lithium Off-label 6.2 11 reviews
Rx D N X

Generic name: lithium systemic

Drug class: antimanic agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

divalproex sodium Off-label 6.0 3 reviews
Rx D N X

Generic name: divalproex sodium systemic

Drug class: fatty acid derivative anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off-label: Yes

alprazolam Off-label 5.0 2 reviews
Rx D 4 X

Generic name: alprazolam systemic

Drug class: benzodiazepines

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

carbamazepine Off-label 5.0 2 reviews
Rx D N X

Generic name: carbamazepine systemic

Drug class: dibenzazepine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

risperidone Off-label 4.9 18 reviews
Rx C N X

Generic name: risperidone systemic

Drug class: atypical antipsychotics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

haloperidol Off-label 3.0 3 reviews
Rx C N X

Generic name: haloperidol systemic

Drug class: miscellaneous antipsychotic agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off-label: Yes

Learn more about Borderline Personality Disorder

IBM Watson Micromedex

Symptoms and treatments

Mayo Clinic Reference

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription Only.
OTC Over the Counter.
Rx/OTC Prescription or Over the Counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.