L-Methylfolate Dosage

Usual Adult Dose for Folic Acid Deficiency

L-methylfolate (in the 7.5 mg or 15 mg strength marketed as Deplin tablets) is approved by the FDA for the distinct nutritional requirements of individuals who have suboptimal L-methylfolate levels in the cerebrospinal fluid, plasma, and/or red blood cells and have major depressive disorder (MDD) with particular emphasis as adjunctive support for individuals who are on an antidepressant.
Dose: 7.5 mg or 15 mg orally once daily

L-methylfolate (in the 7.5 mg or 15 mg strength marketed as Deplin tablets) is also approved by the FDA for the distinct nutritional requirements of individuals who have suboptimal L-methylfolate levels in the cerebrospinal fluid, plasma, and/or red blood cells and have schizophrenia who present with negative symptoms and/or cognitive impairment, with particular emphasis as an adjunctive support for individuals who have stabilized on antipsychotics.
Dose: 7.5 mg or 15 mg orally once daily

L-methylfolate (in a 1 mg strength marketed as Zervalx tablets) is approved by the FDA as an orally administered prescription medical food for the dietary management of:
1) intermediate to higher risk pregnancies which require an increased dietary folate intake
2) hemolytic, megaloblastic, and/or sickle cell anemia complicated by folate deficiency
Dose: 1 mg orally once daily

Usual Adult Dose for Hyperhomocysteinemia

L-methylfolate (in a 1 mg strength marketed as Zervalx tablets) is approved by the FDA as an orally administered prescription medical food for the dietary management of:
1) preconception hyperhomocysteinemia
2) methotrexate induced plasma hyperhomocysteinemia
Dose: 1 mg orally once daily

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dialysis

Data not available