L-methylfolate Alternatives Compared
| L-methylfolate | Cymbalta | Bupropion |
|
|---|
| L-methylfolate | Cymbalta duloxetine | Bupropion |
|
|||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Prescribed for Folic Acid Deficiency, Hyperhomocysteinemia, Depression. May also be prescribed off label for Borderline Personality Disorder. |
Cymbalta has antidepressant, anti-anxiety, and pain-relieving properties; however, it has been associated with a discontinuation syndrome on withdrawal even when tapered. Prescribed for Chronic Pain... View more |
Bupropion may be used in the treatment of depression or as an aid to smoking cessation; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black... View more |
Choose a suggestion below Depression
Popular Comparisons
|
|||||||||||||||
| More about L-methylfolate | More about Cymbalta (duloxetine) | More about Bupropion | ||||||||||||||||
| Generic Status | ||||||||||||||||||
| Availability | ||||||||||||||||||
|
Prescription only |
Prescription only |
Prescription only |
||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
|
L-methylfolate has an average rating of 7.7 out of 10 from a total of 151 ratings on Drugs.com. 73% of reviewers reported a positive effect, while 16% reported a negative effect. |
Cymbalta has an average rating of 6.3 out of 10 from a total of 1663 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 30% reported a negative effect. |
Bupropion has an average rating of 7.0 out of 10 from a total of 2578 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 20% reported a negative effect. |
||||||||||||||||
| Drug Class | ||||||||||||||||||
| Side Effects | ||||||||||||||||||
|
See the full l-methylfolate side effects document. |
Common side effects include: asthenia, constipation, diarrhea, dizziness, drowsiness, fatigue, hypersomnia, insomnia, nausea, sedated state, headache, xerostomia. See the full Cymbalta side effects document. |
Commonly reported side effects include: insomnia, nausea, pharyngitis, weight loss, constipation, dizziness, headache, xerostomia. See the full bupropion side effects document. |
||||||||||||||||
| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
|
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Cymbalta prices and generic prices |
View all bupropion prices |
||||||||||||||||
| Dosage Form(s) Available | ||||||||||||||||||
|
|
|
||||||||||||||||
| Brand Names | ||||||||||||||||||
| Denovo, Deplin, Duleek-DP, Elfolate, L-Methylfolate Forte, XaQuil XR | Other duloxetine brands include: Drizalma Sprinkle, Irenka | Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||
|
N/A |
17 hours |
30 hours |
||||||||||||||||
| CSA Schedule** View glossary of terms | ||||||||||||||||||
|
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
||||||||||||||||
| Pregnancy Category | ||||||||||||||||||
|
Category N
Not classified
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
||||||||||||||||
| Drug Interactions | ||||||||||||||||||
|
A total of 25 drugs are known to interact with l-methylfolate:
|
A total of 574 drugs are known to interact with Cymbalta:
|
A total of 425 drugs are known to interact with bupropion:
|
||||||||||||||||
| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
|
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
|
|
||||||||||||||||
| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
|
N/A |
N/A |
December 30, 1985 |
||||||||||||||||
| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||
|
N/A |
N/A |
N/A |
||||||||||||||||
| More Information | ||||||||||||||||||
| Patient resources | ||||||||||||||||||
| Professional Resources | ||||||||||||||||||
|
N/A |
N/A |
|||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||
|
||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.