L-methylfolate Alternatives Compared
| L-methylfolate | Rexulti (brexpiprazole) | Bupropion |
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| L-methylfolate | Rexulti (brexpiprazole) | Bupropion |
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Prescription and OTC
Prescribed for Folate Deficiency, Hyperhomocysteinemia, Depression, Borderline Personality Disorder. L-methylfolate may also be used for purposes not listed in this medication guide. |
Prescription only
Rexulti is an atypical antipsychotic that may be used to treat adults with schizophrenia or depression, or used to relieve agitation associated with dementia in Alzheimer's disease. Most people... View more |
Prescription only
Bupropion may be used in the treatment of depression or as an aid to smoking cessation; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black... View more |
Related suggestions Depression
Popular comparisons
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| More about L-methylfolate | More about Rexulti (brexpiprazole) | More about Bupropion | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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L-methylfolate has an average rating of 7.8 out of 10 from a total of 166 ratings on Drugs.com. 73% of reviewers reported a positive effect, while 16% reported a negative effect. |
Rexulti has an average rating of 6.6 out of 10 from a total of 490 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 26% reported a negative effect. |
Bupropion has an average rating of 7.0 out of 10 from a total of 2900 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 20% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||
View all L-methylfolate side effects |
View all Rexulti side effects |
View all Bupropion side effects |
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| Drug Class | ||||||||||||||||||
| Generic Availability | ||||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Rexulti prices |
View all Bupropion prices |
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| Dosage Forms | ||||||||||||||||||
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| Brand Names | ||||||||||||||||||
| Denovo, Deplin, Duleek-DP, Elfolate, L-Methylfolate Forte, XaQuil XR |
N/A |
Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||
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N/A |
91 hours |
30 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 25 drugs are known to interact with L-methylfolate:
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A total of 600 drugs are known to interact with Rexulti:
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A total of 559 drugs are known to interact with Bupropion:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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N/A |
July 10, 2015 |
December 30, 1985 |
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| WADA Class View classifications | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
| Patient Resources | ||||||||||||||||||
| Professional Resources | ||||||||||||||||||
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N/A |
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| Related Treatment Guide | ||||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.