Comparing Deplin vs L-methylfolate

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Deplin (l-methylfolate)	L-methylfolate	Enter another drug to compare

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Deplin (l-methylfolate)	L-methylfolate	Enter another drug to compare
Prescription only Prescribed for Folate Deficiency, Hyperhomocysteinemia, Depression. Deplin may also be used for purposes not listed in this medication guide.	Prescription and OTC Prescribed for Folate Deficiency, Hyperhomocysteinemia, Depression, Borderline Personality Disorder. L-methylfolate may also be used for purposes not listed in this medication guide.	Related suggestions Depression Bupropion Sertraline Cymbalta Lexapro Zoloft Fluoxetine Folate Deficiency Folic acid Folacin-800 FA-8 Elfolate XaQuil XR Denovo Hyperhomocysteinemia Folbic Multivitamin Folbee Renal Caps Folplex 2.2 Folgard RX Popular comparisons Deplin vs multivitamin Deplin vs Folbic
More about Deplin (l-methylfolate)	More about L-methylfolate
Ratings & Reviews
Deplin has an average rating of 7.7 out of 10 from a total of 114 ratings on Drugs.com. 70% of reviewers reported a positive effect, while 16% reported a negative effect.	L-methylfolate has an average rating of 7.8 out of 10 from a total of 166 ratings on Drugs.com. 73% of reviewers reported a positive effect, while 16% reported a negative effect.
View all 114 reviews	View all 166 reviews
Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.
Anxiety (9.6%) Depression (5.3%) Headaches (3.5%) View all Deplin side effects	Anxiety (10.2%) Depression (4.2%) Insomnia (3.6%) Headaches (2.4%) View all L-methylfolate side effects
Drug Class
Vitamins	Vitamins
Generic Availability
N/A	Lower cost generic
Pricing and Coupons * Prices are without insurance
We could not find an exact match for this medicine. Try searching the Price Guide directly.	We could not find an exact match for this medicine. Try searching the Price Guide directly.
Get free Discount Card	Get free Discount Card

Dosage Forms
Oral capsule	Oral capsule Oral tablet
Brand Names
Other l-methylfolate brands include: Denovo, Duleek-DP, Elfolate, L-Methylfolate Forte, XaQuil XR	Denovo, Deplin, Duleek-DP, Elfolate, L-Methylfolate Forte, XaQuil XR
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.
N/A	N/A
CSA Schedule ¹ View glossary of CSA terms
N Not a controlled drug Is not subject to the Controlled Substances Act.	N Not a controlled drug Is not subject to the Controlled Substances Act.
Pregnancy Category
N Category N Not classified See the full pregnancy warnings document.	N Category N Not classified See the full pregnancy warnings document.
Drug Interactions
A total of 25 drugs are known to interact with Deplin: 3 major drug interactions (6 brand and generic names) 21 moderate drug interactions (140 brand and generic names) 1 minor drug interactions (4 brand and generic names)	A total of 25 drugs are known to interact with L-methylfolate: 3 major drug interactions (6 brand and generic names) 21 moderate drug interactions (140 brand and generic names) 1 minor drug interactions (4 brand and generic names)
Alcohol/Food/Lifestyle Interactions
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.	No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
Disease Interactions
Bipolar disorder	Bipolar disorder
First Approval Date
N/A	N/A
WADA Class View classifications
N/A	N/A
More Information
Side effects Drug interactions Dosage Pregnancy warnings Drug images Support group En español	Side effects Drug interactions Dosage Pregnancy warnings Drug images Support group En español
Patient Resources
Deplin uses	L-methylfolate uses
Professional Resources
N/A	N/A
Related Treatment Guide
Folate Deficiency Hyperhomocysteinemia Depression	Folate Deficiency Hyperhomocysteinemia Depression Borderline Personality Disorder

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

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Comparing Deplin vs L-methylfolate

See also:

Lexapro

Abilify

Rexulti

Zoloft

Seroquel

Prozac

Cymbalta

Wellbutrin

Zyprexa

Celexa

Further information

Comparing Deplin vs L-methylfolate

See also:

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