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Deplin Disease Interactions

There is 1 disease interaction with Deplin (l-methylfolate).

Moderate

L-methylfolate (applies to Deplin) bipolar disorder

Moderate Potential Hazard, Moderate plausibility.

L-methylfolate should be used with caution in patients with a history of bipolar disorder. Patients with depressive symptoms should be adequately screened to determine if they are at risk for bipolar disorder since mood elevation in this population is possible.

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Deplin drug interactions

There are 25 drug interactions with Deplin (l-methylfolate).

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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