Lithium Interactions
There are 720 drugs known to interact with lithium, along with 12 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 185 are major, 498 are moderate, and 37 are minor.
- View all 720 medications that may interact with lithium
- View lithium alcohol/food interactions (1)
- View lithium disease interactions (12)
Most frequently checked interactions
View interaction reports for lithium and the medicines listed below.
- Abilify (aripiprazole)
- Adderall (amphetamine / dextroamphetamine)
- Ambien (zolpidem)
- Ativan (lorazepam)
- Benadryl (diphenhydramine)
- Celexa (citalopram)
- Cymbalta (duloxetine)
- Depakote (divalproex sodium)
- Effexor XR (venlafaxine)
- Geodon (ziprasidone)
- Klonopin (clonazepam)
- Lamictal (lamotrigine)
- Latuda (lurasidone)
- Lexapro (escitalopram)
- Lyrica (pregabalin)
- Prozac (fluoxetine)
- Seroquel (quetiapine)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Topamax (topiramate)
- Valium (diazepam)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Vyvanse (lisdexamfetamine)
- Wellbutrin (bupropion)
- Wellbutrin XL (bupropion)
- Xanax (alprazolam)
- Zoloft (sertraline)
- Zyprexa (olanzapine)
- Zyrtec (cetirizine)
Lithium alcohol/food interactions
There is 1 alcohol/food interaction with lithium.
Lithium disease interactions
There are 12 disease interactions with lithium which include:
- dementia
- cardiac disease
- dehydration
- diarrhea/hyperhidrosis
- hypothyroidism
- renal dysfunction
- sodium depletion
- previous neuroleptic malignant syndrome (NMS)
- seizure disorders
- fever
- hyperprolactinemia/breast cancer
- neutropenia
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
