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Medications for Migraine

Other names: Basilar Artery Migraine; Basilar-Type Migraine; Complicated Migraine; Hemiplegic Migraine; Migraine Headache

Migraine headaches are a type of headache that some people get repeatedly over time. Migraines are different from other headaches because they occur with symptoms such as nausea, vomiting, or sensitivity to light.

Some people who get migraines have warning symptoms, called an aura, before the actual headache begins. Most people, however, do not have such warning symptoms.

Drugs used to treat Migraine

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
Goody's Extra Strength 10 2 reviews
OTC N N X

Generic name: acetaminophen / aspirin / caffeine systemic

Drug class: analgesic combinations

For consumers: dosage, interactions, side effects

Migergot 10 6 reviews
Rx X N

Generic name: caffeine / ergotamine systemic

Drug class: antimigraine agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

acetaminophen / aspirin / caffeine / salicylamide 9.9 7 reviews
Rx/OTC N N X

Generic name: acetaminophen / aspirin / caffeine / salicylamide systemic

Brand name:  Painaid

Drug class: analgesic combinations

For consumers: dosage, interactions, side effects

methylergonovine Off-label 9.8 10 reviews
Rx C N

Generic name: methylergonovine systemic

Brand name:  Methergine

Drug class: uterotonic agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

Off-label: Yes

Methergine Off-label 9.7 8 reviews
Rx C N

Generic name: methylergonovine systemic

Drug class: uterotonic agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Off-label: Yes

Painaid 9.5 2 reviews
Rx/OTC N N X

Generic name: acetaminophen / aspirin / caffeine / salicylamide systemic

Drug class: analgesic combinations

For consumers: dosage, interactions, side effects

Butalbital Compound 9.3 22 reviews
Rx C 3 X

Generic name: aspirin / butalbital / caffeine systemic

Drug class: analgesic combinations

For consumers: dosage, interactions, side effects

caffeine / ergotamine 9.1 23 reviews
Rx X N

Generic name: caffeine / ergotamine systemic

Brand names:  Cafergot, Migergot

Drug class: antimigraine agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

frovatriptan 9.1 49 reviews
Rx C N

Generic name: frovatriptan systemic

Brand name:  Frova

Drug class: antimigraine agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Treximet 9.1 88 reviews
Rx C N X

Generic name: naproxen / sumatriptan systemic

Drug class: antimigraine agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Axert 9.0 28 reviews
Rx C N

Generic name: almotriptan systemic

Drug class: antimigraine agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Ergomar 9.0 1 review
Rx X N

Generic name: ergotamine systemic

Drug class: antimigraine agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Frova 9.0 41 reviews
Rx C N

Generic name: frovatriptan systemic

Drug class: antimigraine agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

naproxen / sumatriptan 9.0 95 reviews
Rx C N X

Generic name: naproxen / sumatriptan systemic

Brand name:  Treximet

Drug class: antimigraine agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

Vanquish 9.0 2 reviews
OTC N N X

Generic name: acetaminophen / aspirin / caffeine systemic

Drug class: analgesic combinations

For consumers: dosage, interactions, side effects

almotriptan 8.9 32 reviews
Rx C N

Generic name: almotriptan systemic

Brand name:  Axert

Drug class: antimigraine agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

aspirin / butalbital / caffeine 8.8 82 reviews
Rx C 3 X

Generic name: aspirin / butalbital / caffeine systemic

Brand names:  Butalbital Compound, Fiorinal

Drug class: analgesic combinations

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

Maxalt 8.8 115 reviews
Rx C N

Generic name: rizatriptan systemic

Drug class: antimigraine agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Amerge 8.7 28 reviews
Rx C N

Generic name: naratriptan systemic

Drug class: antimigraine agents

For consumers: dosage, interactions, side effects

Maxalt-MLT 8.7 71 reviews
Rx C N

Generic name: rizatriptan systemic

Drug class: antimigraine agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

naratriptan 8.6 45 reviews
Rx C N

Generic name: naratriptan systemic

Brand name:  Amerge

Drug class: antimigraine agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Relpax 8.6 146 reviews
Rx C N

Generic name: eletriptan systemic

Drug class: antimigraine agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Cafergot 8.5 13 reviews
Rx X N

Generic name: caffeine / ergotamine systemic

Drug class: antimigraine agents

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Fiorinal 8.5 48 reviews
Rx C 3 X

Generic name: aspirin / butalbital / caffeine systemic

Drug class: analgesic combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Imitrex Statdose 8.5 17 reviews
Rx C N

Generic name: sumatriptan systemic

Drug class: antimigraine agents

For consumers: dosage, interactions, side effects

Topics under Migraine

Alternative treatments for Migraine

The following products are considered to be alternative treatments or natural remedies for Migraine. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Migraine.

Learn more about Migraine

IBM Watson Micromedex

Symptoms and treatments

Mayo Clinic Reference

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription Only.
OTC Over the Counter.
Rx/OTC Prescription or Over the Counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.