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Methylergonovine Dosage

Medically reviewed by Last updated on Apr 14, 2022.

Applies to the following strengths: 0.2 mg; 0.2 mg/mL

Usual Adult Dose for Postpartum Bleeding

0.2 mg IM after delivery of the placenta or during the puerperium; may be repeated at intervals of 2 to 4 hours as required

0.2 mg orally 3 or 4 times a day for a maximum of 1 week during the puerperium


  • Under full obstetric supervision, this drug may be given parenterally during the second stage of labor following delivery of the anterior shoulder.
  • IV administration should be avoided unless administration is considered life-saving; IV dosing is the same as IM, give IV slowly over at least 60 seconds

  • For routine management of uterine atony, hemorrhage and subinvolution of the uterus following delivery of the placenta.
  • For control of uterine hemorrhage in the second stage of labor following delivery of the anterior shoulder.

Renal Dose Adjustments

Use caution

Liver Dose Adjustments

Use caution



  • Hypersensitivity
  • Hypertension
  • Toxemia
  • Pregnancy

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments

Administration advice:

  • For oral and IM administration; avoid intra-arterial or periarterial administration
  • Routine IV administration should be avoided because of the possibility of sudden hypertensive and cerebrovascular accidents; if administered IV, give slowly over no less than 60 seconds and closely monitor blood pressure

Storage requirements:
  • Protect from light

  • Methergine injection should be stored separately from medications intended for neonatal administration to avoid inadvertent administration to newborn infants.

  • Monitor BP, especially if IV administration is necessary

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.