Methylergonovine Dosage

Medically reviewed by Drugs.com. Last updated on Apr 4, 2025.

Usual Adult Dose for Postpartum Bleeding

Parenteral:
0.2 mg IM after delivery of the placenta or during the puerperium; may be repeated at intervals of 2 to 4 hours as required

Orally:
0.2 mg orally 3 or 4 times a day for a maximum of 1 week during the puerperium

Comments:

• Under full obstetric supervision, this drug may be given parenterally during the second stage of labor following delivery of the anterior shoulder.
• IV administration should be avoided unless administration is considered life-saving; IV dosing is the same as IM, give IV slowly over at least 60 seconds

Uses:

• For routine management of uterine atony, hemorrhage and subinvolution of the uterus following delivery of the placenta.
• For control of uterine hemorrhage in the second stage of labor following delivery of the anterior shoulder.

Renal Dose Adjustments

Use caution

Liver Dose Adjustments

Use caution

Precautions

CONTRAINDICATIONS:

• Hypersensitivity
• Hypertension
• Toxemia
• Pregnancy

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• For oral and IM administration; avoid intra-arterial or periarterial administration
• Routine IV administration should be avoided because of the possibility of sudden hypertensive and cerebrovascular accidents; if administered IV, give slowly over no less than 60 seconds and closely monitor blood pressure

Storage requirements:

• Protect from light

General:

• Methergine injection should be stored separately from medications intended for neonatal administration to avoid inadvertent administration to newborn infants.

Monitoring:

• Monitor BP, especially if IV administration is necessary

See also:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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