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Caffeine / Ergotamine Dosage

Medically reviewed by Drugs.com. Last updated on Sep 26, 2023.

Applies to the following strengths: 100 mg-1 mg; 100 mg-2 mg

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Migraine

Oral: Ergotamine 1 mg-caffeine 100 mg per tablet:
Initial dose: 2 tablets orally at first sign of an attack; 1 additional tablet every half-hour as needed not to exceed maximum doses
Maximum doses: 6 tablets per attack; 10 tablets per 7-day period

Rectal: Ergotamine 2 mg-caffeine 100 mg per suppository:
Initial dose: 1 suppository rectally at first sign of a migraine attack; 1 additional suppository may be administered after 1 hour if needed for full relief
Maximum dose: 2 suppositories per attack; 5 suppositories per 7-day period

Comments:


Use: To abort or prevent vascular headaches, such as a migraine, migraine variants, or "histaminic cephalalgia".

Renal Dose Adjustments

Contraindicated

Liver Dose Adjustments

Contraindicated

Precautions

US BOXED WARNING: CONCOMITANT ADMINISTRATION WITH POTENT CYP450 3A4 INHIBITORS:


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available, however this drug is contraindicated in patients with renal impairment

Other Comments

Administration advice:


Storage requirements:

General:

Monitoring:

Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.