Frovatriptan Side Effects

Medically reviewed by Drugs.com. Last updated on Jan 27, 2023.

Summary

More frequently reported side effects include: dizziness, fatigue, paresthesia, and flushing. Continue reading for a comprehensive list of adverse effects.

Applies to frovatriptan: oral tablet.

Serious side effects of Frovatriptan

Along with its needed effects, frovatriptan may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking frovatriptan:

Less common

• Changes in vision
• chest pain
• fast, irregular, pounding, or racing heartbeat or pulse
• increased sweating

Incidence not known

• Abdominal or stomach pain
• agitation
• bloody diarrhea
• cold fingers or toes
• confusion
• cough
• diarrhea
• difficulty swallowing
• dizziness
• fainting
• fever
• headache, sudden, severe, and continuing
• large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
• numbness or tingling of the fingers or toes
• overactive reflexes
• pain spreading to the left shoulder
• paleness or cold feeling in the fingertips and toes
• poor coordination
• puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
• restlessness
• shivering
• skin rash, hives, or itching skin
• talking or acting with excitement you cannot control
• tightness in the chest, throat, neck, and jaw
• tingling or pain in the fingers or toes when exposed to cold
• trembling or shaking
• twitching
• unusual tiredness or weakness
• weakness in the legs

Other side effects of Frovatriptan

Some side effects of frovatriptan may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

• Acid or sour stomach
• belching
• bone pain
• continuing ringing or buzzing or other unexplained noise in the ears
• dry mouth
• feeling of warmth
• hearing loss
• heartburn
• hot or cold sensation
• indigestion
• pain or tenderness around the eyes and cheekbones
• redness of the face, neck, arms, and occasionally upper chest
• stomach discomfort or upset
• stuffy or runny nose
• trouble sleeping

Incidence not known

• Seizures

For Healthcare Professionals

Applies to frovatriptan: oral tablet.

General

The most commonly reported adverse events included dizziness, fatigue, paraesthesia, headache, and vascular flushing.^[Ref]

Hypersensitivity

Postmarketing reports: Hypersensitivity reactions including cutaneous disorders, angioedema, and anaphylactic reactions^[Ref]

Cardiovascular

Common (1% to 10%): Flushing, chest discomfort

Uncommon (0.1% to 1%): Palpitations, tachycardia, peripheral coldness, hypertension, chest pain

Rare (0.01% to 0.1%): Bradycardia

Postmarketing reports: Myocardial infarction, coronary arteriospasm^[Ref]

Nervous system

Common (1% to 10%): Dizziness, headache, paresthesia, dysesthesia, hypoesthesia , somnolence

Uncommon (0.1% to 1%): Dysgeusia, tremor, disturbance in attention. lethargy, sedation, vertigo, involuntary muscle contractions

Rare (0.01% to 0.1%): Amnesia hypertonia hypotonia, hyporeflexia, movement disorder

Postmarketing reports: Seizure^[Ref]

Psychiatric

Uncommon (0.1% to 1%): Anxiety, insomnia, confusional state, nervousness, agitation, depression, depersonalization

Rare (0.01% to 0.1%): Abnormal dreams, personality disorder^[Ref]

Gastrointestinal

Common (1% to 10%): Dry mouth, dyspepsia, vomiting, nausea, abdominal pain, diarrhea

Uncommon (0.1% to 1%): Dysphagia, flatulence, constipation, anorexia, esophagospasm, increased salivation

Rare (0.01% to 0.1%): Change in bowel habits, chelitis, eructation, gastroesophageal reflux, hiccough, peptic ulcer, salivary gland pain, stomatitis, toothache, lip blister, lip pain , oral mucosal blistering, peptic ulcer, salivary gland pain^[Ref]

Musculoskeletal

Common (1% to 10%): Skeletal pain

Uncommon (0.1% to 1%): Musculoskeletal stiffness, musculoskeletal pain, pain in extremity, back pain, arthralgia^[Ref]

Respiratory

Common (1% to 10%): Throat tightness

Uncommon (0.1% to 1%): Rhinitis, sinusitis, pharyngolaryngeal pain

Rare (0.01% to 0.1%): Epistasis, hiccups, hyperventilation, respiratory disorder, throat irritation^[Ref]

Ocular

Common (1% to 10%): Visual disturbance

Uncommon (0.1% to 1%): Eye pain, eye irritation, photophobia

Rare (0.01% to 0.1%): Night blindness^[Ref]

Dermatologic

Common (1% to 10%): Hyperhidrosis

Uncommon (0.1% to 1%): Pruritus

Rare (0.01% to 0.1%): Erythema, piloerection, urticaria, purpura^[Ref]

Other

Common (1% to 10%): Fatigue, hot or cold sensation, tinnitus

Uncommon (0.1% to 1%): Ear pain, ear discomfort, ear disorder, ear pruritus, hyperacusis, feeling hot temperature intolerance, asthenia, sluggishness, energy increased, malaise

Rare (0.01% to 0.1%): Pyrexia^[Ref]

Genitourinary

Uncommon (0.1% to 1%): Increased micturition frequency, polyuria

Rare (0.01% to 0.1%): Nocturia, renal pain, abnormal urine analysis^[Ref]

Metabolic

Uncommon (0.1% to 1%): Dehydration, thirst

Rare (0.01% to 0.1%): Hypoglycemia^[Ref]

Hematologic

Rare (0.01% to 0.1%): Lymphadenopathy^[Ref]

Hepatic

Rare (0.01% to 0.1%): Increased blood bilirubin^[Ref]

Endocrine

Uncommon (0.1% to 1%): Breast tenderness^[Ref]

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer