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Frovatriptan Side Effects

Medically reviewed by Last updated on Dec 9, 2023.

Applies to frovatriptan: oral tablet.

Serious side effects of Frovatriptan

Along with its needed effects, frovatriptan may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking frovatriptan:

Less common

Incidence not known

Other side effects of Frovatriptan

Some side effects of frovatriptan may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Incidence not known

For Healthcare Professionals

Applies to frovatriptan: oral tablet.


The most commonly reported adverse events included dizziness, fatigue, paraesthesia, headache, and vascular flushing.[Ref]


Postmarketing reports: Hypersensitivity reactions including cutaneous disorders, angioedema, and anaphylactic reactions[Ref]


Common (1% to 10%): Flushing, chest discomfort

Uncommon (0.1% to 1%): Palpitations, tachycardia, peripheral coldness, hypertension, chest pain

Rare (0.01% to 0.1%): Bradycardia

Postmarketing reports: Myocardial infarction, coronary arteriospasm[Ref]

Nervous system

Common (1% to 10%): Dizziness, headache, paresthesia, dysesthesia, hypoesthesia , somnolence

Uncommon (0.1% to 1%): Dysgeusia, tremor, disturbance in attention. lethargy, sedation, vertigo, involuntary muscle contractions

Rare (0.01% to 0.1%): Amnesia hypertonia hypotonia, hyporeflexia, movement disorder

Postmarketing reports: Seizure[Ref]


Uncommon (0.1% to 1%): Anxiety, insomnia, confusional state, nervousness, agitation, depression, depersonalization

Rare (0.01% to 0.1%): Abnormal dreams, personality disorder[Ref]


Common (1% to 10%): Dry mouth, dyspepsia, vomiting, nausea, abdominal pain, diarrhea

Uncommon (0.1% to 1%): Dysphagia, flatulence, constipation, anorexia, esophagospasm, increased salivation

Rare (0.01% to 0.1%): Change in bowel habits, chelitis, eructation, gastroesophageal reflux, hiccough, peptic ulcer, salivary gland pain, stomatitis, toothache, lip blister, lip pain , oral mucosal blistering, peptic ulcer, salivary gland pain[Ref]


Common (1% to 10%): Skeletal pain

Uncommon (0.1% to 1%): Musculoskeletal stiffness, musculoskeletal pain, pain in extremity, back pain, arthralgia[Ref]


Common (1% to 10%): Throat tightness

Uncommon (0.1% to 1%): Rhinitis, sinusitis, pharyngolaryngeal pain

Rare (0.01% to 0.1%): Epistasis, hiccups, hyperventilation, respiratory disorder, throat irritation[Ref]


Common (1% to 10%): Visual disturbance

Uncommon (0.1% to 1%): Eye pain, eye irritation, photophobia

Rare (0.01% to 0.1%): Night blindness[Ref]


Common (1% to 10%): Hyperhidrosis

Uncommon (0.1% to 1%): Pruritus

Rare (0.01% to 0.1%): Erythema, piloerection, urticaria, purpura[Ref]


Common (1% to 10%): Fatigue, hot or cold sensation, tinnitus

Uncommon (0.1% to 1%): Ear pain, ear discomfort, ear disorder, ear pruritus, hyperacusis, feeling hot temperature intolerance, asthenia, sluggishness, energy increased, malaise

Rare (0.01% to 0.1%): Pyrexia[Ref]


Uncommon (0.1% to 1%): Increased micturition frequency, polyuria

Rare (0.01% to 0.1%): Nocturia, renal pain, abnormal urine analysis[Ref]


Uncommon (0.1% to 1%): Dehydration, thirst

Rare (0.01% to 0.1%): Hypoglycemia[Ref]


Rare (0.01% to 0.1%): Lymphadenopathy[Ref]


Rare (0.01% to 0.1%): Increased blood bilirubin[Ref]


Uncommon (0.1% to 1%): Breast tenderness[Ref]


1. (2001) "Product Information. Frova (frovatriptan)." Endo Laboratories LLC

2. Cerner Multum, Inc. "UK Summary of Product Characteristics."

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.