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Ergomar Side Effects

Generic name: ergotamine

Medically reviewed by Last updated on Nov 21, 2023.

Note: This document contains side effect information about ergotamine. Some dosage forms listed on this page may not apply to the brand name Ergomar.

Applies to ergotamine: oral tablets, rectal suppositories, sublingual tablets.


  • Possible serious and/or life-threatening cerebral and/or peripheral ischemia when used concomitantly with potent CYP3A4 inhibitors (see Interactions); concomitant use contraindicated.138 139 140

Side effects include:

Nausea, vomiting, abdominal pain, numbness and tingling of the fingers and toes, muscle pain in the extremities, weakness in the legs.

For Healthcare Professionals

Applies to ergotamine: compounding powder, sublingual tablet.


The most commonly reported adverse effects have included nausea and vomiting.[Ref]


Frequency not reported: Ischemia, cyanosis, absence of pulse, cold extremities, precordial distress, EKG changes, gangrene, transient tachycardia, bradycardia, hypertension

Serious vasoconstrictive have occurred, more commonly with long-term therapy at relatively high doses, however, they have been reported with short-term or normal doses.

Nervous system

Rare (less than 0.1%): Cerebral ischemia

Frequency not reported: Paresthesias, numbness, weakness

Reports of cerebral ischemia, including 1 death, have been reported for patients receiving ergotamine and protease inhibitors concomitantly. A black box warning is now required labeling for these drugs.


Frequency not reported: Nausea, vomiting


Frequency not reported: Musculoskeletal aches, pains, and cramps


Frequency not reported: Vertigo


Frequency not reported: Localized edema, itching


1. (2013) "Product Information. Ergomar (ergotamine)." Rosedale Therapeutics

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.