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Protease inhibitors

What are Protease inhibitors?

Protease inhibitors are synthetic drugs that inhibit the action of HIV-1 protease, an enzyme that cleaves two precursor proteins into smaller fragments. These fragments are needed for viral growth, infectivity and replication. Protease inhibitors bind to the active site of the protease enzyme and prevent the maturation of the newly produced virions so that they remain non-infectious.

Protease inhibitors are used in the treatment of human immunodeficiency virus (HIV infection) and acquired immune deficiency syndrome (AIDS).

List of Protease inhibitors:

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Drug Name Reviews Avg. Ratings
Victrelis (Pro)
generic name: boceprevir
3 reviews
   
10
Olysio (Pro)
generic name: simeprevir
4 reviews
   
9.7
Lexiva (Pro)
generic name: fosamprenavir
0 reviews
   
9.0
Kaletra (Pro)
generic name: lopinavir / ritonavir
3 reviews
   
8.8
Prezista (Pro)
generic name: darunavir
4 reviews
   
8.4
Incivek (Pro)
generic name: telaprevir
7 reviews
   
8.2
Aptivus (Pro)
generic name: tipranavir
0 reviews
   
7.0
Norvir (Pro)
generic name: ritonavir
1 review
   
6.0
Reyataz (Pro)
generic name: atazanavir
1 review
   
5.8
Viracept (Pro)
generic name: nelfinavir
0 reviews
   
5.0
Agenerase
generic name: amprenavir
0 reviews
   
4.5
Crixivan (Pro)
generic name: indinavir
0 reviews
   
2.0
Fortovase
generic name: saquinavir
0 reviews
   
1.0
Invirase (Pro)
generic name: saquinavir
0 reviews
   
1.0

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

See Also

Medical conditions associated with protease inhibitors:

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