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Protease inhibitors

What are Protease inhibitors?

Protease inhibitors are synthetic drugs that inhibit the action of HIV-1 protease, an enzyme that cleaves two precursor proteins into smaller fragments. These fragments are needed for viral growth, infectivity and replication. Protease inhibitors bind to the active site of the protease enzyme and prevent the maturation of the newly produced virions so that they remain non-infectious.

Protease inhibitors are used in the treatment of human immunodeficiency virus (HIV infection) and acquired immune deficiency syndrome (AIDS).

List of Protease inhibitors:

View by  Brand | Generic
Drug Name Avg. Rating Reviews
Incivek (Pro)
Generic name: telaprevir
8.2
7 reviews
Prezista (Pro)
Generic name: darunavir
8.4
4 reviews
Olysio (Pro)
Generic name: simeprevir
9.7
4 reviews
Victrelis (Pro)
Generic name: boceprevir
10
3 reviews
Norvir (Pro)
Generic name: ritonavir
4.6
3 reviews
Kaletra (Pro)
Generic name: lopinavir / ritonavir
8.8
3 reviews
Reyataz (Pro)
Generic name: atazanavir
5.8
1 review
Crixivan (Pro)
Generic name: indinavir
1.7
1 review
Viracept (Pro)
Generic name: nelfinavir
5.0
No reviews
Lexiva (Pro)
Generic name: fosamprenavir
9.0
No reviews
Invirase (Pro)
Generic name: saquinavir
1.0
No reviews
Fortovase
Generic name: saquinavir
1.0
No reviews
Aptivus (Pro)
Generic name: tipranavir
7.0
No reviews
Agenerase
Generic name: amprenavir
4.5
No reviews
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

See Also

Medical conditions associated with protease inhibitors:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.