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Protease inhibitors

What are Protease inhibitors?

Protease inhibitors are synthetic drugs that inhibit the action of HIV-1 protease, an enzyme that cleaves two precursor proteins into smaller fragments. These fragments are needed for viral growth, infectivity and replication. Protease inhibitors bind to the active site of the protease enzyme and prevent the maturation of the newly produced virions so that they remain non-infectious.

Protease inhibitors are used in the treatment of human immunodeficiency virus (HIV infection) and acquired immune deficiency syndrome (AIDS).

List of Protease inhibitors

View by  Generic | Brand
Drug Name Avg. Rating Reviews
lopinavir / ritonavir systemic (Pro)
Brand name: Kaletra
7.0
5 reviews
darunavir systemic (Pro)
Brand name: Prezista
7.8
5 reviews
atazanavir systemic (Pro)
Brand name: Reyataz
8.8
4 reviews
ritonavir systemic (Pro)
Brand name: Norvir
1.0
3 reviews
tipranavir systemic (Pro)
Brand name: Aptivus
No reviews
saquinavir systemic
Brand name: Invirase
No reviews
nelfinavir systemic (Pro)
Brand name: Viracept
No reviews
fosamprenavir systemic (Pro)
Brand name: Lexiva
No reviews
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

See also

Medical conditions treated or associated with protease inhibitors:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.