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Naratriptan Side Effects

Medically reviewed by Last updated on Oct 13, 2022.

Applies to naratriptan: oral tablet.

Serious side effects of Naratriptan

Along with its needed effects, naratriptan may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking naratriptan:

More common

  • Chest pain (severe)
  • heaviness, tightness, or pressure in the chest, throat, or neck
  • sensation of burning, warmth, heat, numbness, tightness, or tingling

Less common

  • Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings

Less common or rare

Other side effects of Naratriptan

Some side effects of naratriptan may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Anxiety
  • bone pain
  • change in taste sensation
  • chills or fever
  • difficulty with sleeping
  • eye problems
  • fainting
  • general feeling of discomfort or illness
  • joint pain
  • muscle or joint stiffness, tightness, or rigidity
  • pounding heartbeat
  • stomach discomfort or pain
  • trembling or shaking of the hands or feet
  • unusual tiredness or weakness

For Healthcare Professionals

Applies to naratriptan: oral tablet.


The most commonly reported adverse reactions have included paresthesias, dizziness, drowsiness, malaise/fatigue, and throat/neck symptoms.[Ref]


Common (1% to 10%): Palpitations, chest pain and discomfort, chest pressure/heaviness

Uncommon (0.1% to 1%): Bradycardia, tachycardia

Very rare (less than 0.01%): Peripheral vascular ischemia, coronary artery vasospasm, transient ischemic ECG changes, angina, myocardial infarctions

Frequency not reported: Acute myocardial infarction, increased blood pressure[Ref]


Common (1% to 10%): Malaise/fatigue, sensations of pain or pressure, heaviness or tightness (maybe of throat/neck/chest), warm-hot sensation, vertigo[Ref]

Nervous system

Common (1% to 10%): Paresthesias, dizziness, drowsiness, headaches

Rare (0.01% to 0.1%): Somnolence[Ref]


Common (1% to 10%): Nausea, vomiting, hyposalivation

Rare (0.01% to 0.1%): Ischemic colitis[Ref]


Uncommon (0.1% to 1%): Visual disturbance, photophobia[Ref]


Common (1% to 10%): Musculoskeletal pain, muscle stiffness, tightness and rigidity[Ref]


Rare (0.01% to 0.1%): Anaphylaxis, hypersensitivity reactions including cutaneous hypersensitivity and angioedema[Ref]


Rare (0.01% to 0.1%): Rash, urticaria, pruritus, facial edema[Ref]


1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. "Product Information. Amerge (naratriptan)." Glaxo Wellcome (2001):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.