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Naratriptan Side Effects

For the Consumer

Applies to naratriptan: oral tablet

As well as its needed effects, naratriptan may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking naratriptan, check with your doctor immediately:

More common:
  • Chest pain (severe)
  • heaviness, tightness, or pressure in the chest, throat, or neck
  • sensation of burning, warmth, heat, numbness, tightness, or tingling
Less common:
  • Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
Less common or rare:
  • Convulsions (seizures)
  • irregular heartbeat
  • slow heartbeat

Minor Side Effects

Some naratriptan side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Less common:
  • Anxiety
  • bone pain
  • change in taste sensation
  • chills or fever
  • difficulty with sleeping
  • eye problems
  • fainting
  • general feeling of discomfort or illness
  • joint pain
  • muscle or joint stiffness, tightness, or rigidity
  • pounding heartbeat
  • stomach discomfort or pain
  • trembling or shaking of the hands or feet
  • unusual tiredness or weakness

For Healthcare Professionals

Applies to naratriptan: oral tablet


The most commonly reported adverse reactions have included paresthesias, dizziness, drowsiness, malaise/fatigue, and throat/neck symptoms.[Ref]


Common (1% to 10%): Palpitations, chest pain and discomfort, chest pressure/heaviness
Uncommon (0.1% to 1%): Bradycardia, tachycardia
Very rare (less than 0.01%): Peripheral vascular ischemia, coronary artery vasospasm, transient ischemic ECG changes, angina, myocardial infarctions
Frequency not reported: Acute myocardial infarction, increased blood pressure[Ref]


Common (1% to 10%): Malaise/fatigue, sensations of pain or pressure, heaviness or tightness (maybe of throat/neck/chest), warm-hot sensation, vertigo[Ref]

Nervous system

Common (1% to 10%): Paresthesias, dizziness, drowsiness, headaches
Rare (0.01% to 0.1%): Somnolence[Ref]


Common (1% to 10%): Nausea, vomiting, hyposalivation
Rare (0.01% to 0.1%): Ischemic colitis[Ref]


Uncommon (0.1% to 1%): Visual disturbance, photophobia[Ref]


Common (1% to 10%): Musculoskeletal pain, muscle stiffness, tightness and rigidity[Ref]


Rare (0.01% to 0.1%): Anaphylaxis, hypersensitivity reactions including cutaneous hypersensitivity and angioedema[Ref]


Rare (0.01% to 0.1%): Rash, urticaria, pruritus, facial edema[Ref]


1. Cerner Multum, Inc. "Australian Product Information." O 0

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. "Product Information. Amerge (naratriptan)." Glaxo Wellcome, Research Triangle Park, NC.

It is possible that some side effects of naratriptan may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.