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Medications for Bipolar Disorder

Drugs associated with Bipolar Disorder

The following drugs and medications are in some way related to, or used in the treatment of this condition.

What is Bipolar Disorder: Bipolar disorder is characterized by periods of excitability (mania) alternating with periods of depression. The "mood swings" between mania and depression are often very abrupt.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
lithium Rx D N X 169 reviews
7.0

Generic name: lithium systemic

Brand name:  Lithobid

Drug class: miscellaneous antipsychotic agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
lamotrigine Rx C N X 432 reviews
8.0

Generic name: lamotrigine systemic

Brand names:  Lamictal, Lamictal ODT, Lamictal CD

Drug class: triazine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
clonazepam Rx D 4 X 73 reviews
8.0

Generic name: clonazepam systemic

Brand name:  Klonopin

Drug class: benzodiazepines, benzodiazepine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
gabapentin Off Label Rx C N X 69 reviews
8.0

Generic name: gabapentin systemic

Drug class: gamma-aminobutyric acid analogs

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
bupropion Off Label Rx C N X 38 reviews
6.0

Generic name: bupropion systemic

Drug class: miscellaneous antidepressants, smoking cessation agents

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
divalproex sodium Rx D N X 141 reviews
6.0

Generic name: divalproex sodium systemic

Brand names:  Depakote, Depakote ER, Depakote Sprinkles

Drug class: fatty acid derivative anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
quetiapine Rx C N X 334 reviews
7.0

Generic name: quetiapine systemic

Brand names:  Seroquel, Seroquel XR

Drug class: atypical antipsychotics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
risperidone Rx C N X 84 reviews
6.0

Generic name: risperidone systemic

Brand names:  Risperdal, Risperdal Consta, Risperdal M-Tab

Drug class: atypical antipsychotics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
sertraline Off Label Rx C N X 25 reviews
7.0

Generic name: sertraline systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
carbamazepine Rx D N X 74 reviews
7.0

Generic name: carbamazepine systemic

Brand names:  Tegretol, Equetro, Tegretol XR

Drug class: dibenzazepine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
citalopram Off Label Rx C N X 5 reviews
7.0

Generic name: citalopram systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
topiramate Off Label Rx D N X 74 reviews
7.0

Generic name: topiramate systemic

Drug class: carbonic anhydrase inhibitor anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
clonidine Off Label Rx C N X 5 reviews
6.0

Generic name: clonidine systemic

Brand names:  Catapres, Catapres-TTS

Drug class: antiadrenergic agents, centrally acting

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
olanzapine Rx C N X 112 reviews
7.0

Generic name: olanzapine systemic

Brand names:  Zyprexa, Zyprexa Zydis, Zyprexa Intramuscular

Drug class: atypical antipsychotics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
oxcarbazepine Off Label Rx C N X 84 reviews
8.0

Generic name: oxcarbazepine systemic

Drug class: dibenzazepine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
venlafaxine Off Label Rx C N X 44 reviews
7.0

Generic name: venlafaxine systemic

Drug class: serotonin-norepinephrine reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
aripiprazole Rx C N X 189 reviews
6.0

Generic name: aripiprazole systemic

Brand names:  Abilify, Abilify Discmelt

Drug class: atypical antipsychotics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
escitalopram Off Label Rx C N X 32 reviews
7.0

Generic name: escitalopram systemic

Drug class: selective serotonin reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
duloxetine Off Label Rx C N X 29 reviews
6.0

Generic name: duloxetine systemic

Drug class: serotonin-norepinephrine reuptake inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
valproic acid Off Label Rx D N X 11 reviews
6.0

Generic name: valproic acid systemic

Drug class: fatty acid derivative anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

Off Label: Yes

 
ziprasidone Rx C N X 146 reviews
5.0

Generic name: ziprasidone systemic

Brand name:  Geodon

Drug class: atypical antipsychotics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
fluoxetine / olanzapine Rx C N X 28 reviews
8.0

Generic name: fluoxetine / olanzapine systemic

Brand name:  Symbyax

Drug class: psychotherapeutic combinations

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, Prescribing Information

 
levetiracetam Off Label Rx C N X 5 reviews
6.0

Generic name: levetiracetam systemic

Drug class: pyrrolidine anticonvulsants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
verapamil Off Label Rx C N X Add review Add

Generic name: verapamil systemic

Drug class: calcium channel blocking agents, group IV antiarrhythmics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
armodafinil Off Label Rx C 4 12 reviews
8.0

Generic name: armodafinil systemic

Drug class: CNS stimulants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Off Label: Yes

 
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Topics under Bipolar Disorder

Learn more about Bipolar Disorder

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N The drug is not subject to the Controlled Substances Act.
1 The drug has a high potential for abuse. The drug has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use of the drug under medical supervision.
2 The drug has a high potential for abuse. The drug has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse of the drug may lead to severe psychological or physical dependence.
3 The drug has a potential for abuse less than the drugs in schedules 1 and 2. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to moderate or low physical dependence or high psychological dependence.
4 The drug has a low potential for abuse relative to the drugs in schedule 3. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to limited physical dependence or psychological dependence relative to the drugs in schedule 3.
5 The drug has a low potential for abuse relative to the drugs in schedule 4. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to limited physical dependence or psychological dependence relative to the drugs in schedule 4.
Alcohol
X Interacts with Alcohol.

Synonym(s): Bipolar Affective Disorder; Bipolar Affective Mood Disorder; Bipolar I Disorder; Bipolar II Disorder; Manic Depression; Manic Depressive Disorder; Manic Depressive Illness; Mood Disorder

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