Generic Name: quetiapine (kwe TYE a peen)
Brand Name: SEROquel, SEROquel XR
What is Seroquel XR?
Seroquel XR is also used together with antidepressant medications to treat major depressive disorder in adults.
Seroquel XR may also be used for purposes not listed in this medication guide.
Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor.
Seroquel XR is not approved for use in older adults with dementia-related psychosis.
Before taking this medicine
You should not use Seroquel XR if you are allergic to it.
Seroquel XR may increase the risk of death in older adults with dementia-related psychosis and is not approved for this use.
Seroquel XR is not approved for use by anyone younger than 10 years old.
Tell your doctor if you have ever had:
high or low blood pressure;
low white blood cell (WBC) counts;
abnormal thyroid tests or prolactin levels;
constipation or urination problems;
glaucoma or cataracts;
high cholesterol or triglycerides;
diabetes (in you or a family member); or
Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.
Taking antipsychotic medicine in the last 3 months of pregnancy may cause withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles in the newborn. If you get pregnant, tell your doctor right away. Do not stop taking Seroquel XR without your doctor's advice.
Seroquel XR may temporarily affect fertility (your ability to have children) in women.
You should not breastfeed while you are using Seroquel XR.
How should I take Seroquel XR?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
High doses or long-term use of quetiapine can cause a serious movement disorder that may not be reversible. The longer you use Seroquel XR, the more likely you are to develop this disorder, especially if you are an older adult. Symptoms of this disorder include tremors or other uncontrollable muscle movements.
You may take Seroquel with or without food.
You should take Seroquel XR without food or with a light meal.
Swallow the tablet whole and do not crush, chew, or break it.
Seroquel XR may cause you to have high blood sugar (hyperglycemia). If you are diabetic, check your blood sugar levels on a regular basis.
Drink plenty of liquids while you are taking Seroquel XR.
Blood pressure may need to be checked often in a child or teenager taking Seroquel XR.
You should not stop using Seroquel XR suddenly. Stopping suddenly may make your condition worse.
This medicine may affect a drug-screening urine test and you may have false results. Tell the laboratory staff that you use Seroquel XR.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Seroquel XR can be fatal.
What should I avoid while taking quetiapine?
Avoid drinking alcohol. Dangerous side effects could occur.
Avoid driving or hazardous activity until you know how Seroquel XR will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.
Avoid becoming overheated or dehydrated during exercise and in hot weather. You may be more prone to heat stroke.
Seroquel XR side effects
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.
Call your doctor at once if you have:
uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement);
mask-like appearance of the face, trouble swallowing, problems with speech;
a light-headed feeling, like you might pass out;
painful or difficult urination;
blurred vision, tunnel vision, eye pain, or seeing halos around lights;
severe nervous system reaction--very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, fainting;
high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or
low white blood cell counts--fever, chills, mouth sores, skin sores, sore throat, cough, trouble breathing, feeling light-headed.
Common side effects may include:
dizziness, drowsiness, tiredness;
lack of energy;
increased appetite, weight gain;
dry mouth; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Seroquel XR?
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
Seroquel XR can cause a serious heart problem. Your risk may be higher if you also use certain other medicines for infections, asthma, heart problems, high blood pressure, depression, mental illness, cancer, malaria, or HIV.
Many drugs can affect Seroquel XR. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.
More about Seroquel XR (quetiapine)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Español
- 182 Reviews
- Generic Availability
- Drug class: atypical antipsychotics
- FDA Alerts (6)
- FDA Approval History
Related treatment guides
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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