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User Reviews for Seroquel XR

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Seroquel XR.

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Condition DownUp Reviews Compare Avg. Ratings DownUp
Bipolar Disorder 74 reviews 28 medications
   
7.4
Depression 42 reviews 79 medications
   
7.3
Schizophrenia 7 reviews 42 medications
   
6.9
Schizoaffective Disorder 6 reviews 27 medications
   
6.0
Major Depressive Disorder 11 reviews 46 medications
   
5.5
Summary of Seroquel XR reviews 140 reviews 6.6

Reviews for Seroquel XR

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For Bipolar Disorder "Gained probably 80 pounds, constantly was ravenous, felt horrible, drowsy and disconnected, and my symptoms were not any better. No thanks"

Anonymous (taken for 1 to 2 years) May 23, 2017

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For Depression "I was on this medication for around 3 years at different doses, anywhere from 50 mgs to 600 mgs. It was a very good medicine and helped a lot with my anxiety and depression and really calmed me down and was very helpful, but the weight gain was a killer. I would try to go off over and over and would have to keep going back to it because I would be in such bad shape without it. I had a love/hate relationship with it. I became pre-diabetic while on it. I finally was able to go off and stay off at one point. It's a great drug, but the side effects are horrible as far as weight gain."

   
8.0

Gastroparesis Girl (taken for 2 to 5 years) May 20, 2017

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For Bipolar Disorder "SeroquelXR has changed my life for the better. I am currently on 400mg once daily. (I also take klonopin before I go to work). For the last 6 months, I have not had to call out sick from work, which was a monthly occurrence before Seroquel. I have not had to take a leave of absence in the last year. I used to have to take 2 six week leaves a year. I feel much more positive about my job and my life in general. It has been a game changer for me. The only down side is the weight gain. It seems to slow your metabolism down and increase your appetite after taking it, making it difficult to loose weight. I am currently not overweight, so the weight gain is a small price to pay. I do have to exercise regularly and watch more carefully what I eat"

   
9.0

B303 May 13, 2017

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For Bipolar Disorder "I don't understand all the negative reviews. For me this pill has worked well. It's calmed me right down and has been blissful at moments. It's expensive unfortunately. As for weight gain, I've noticed that it's pretty neutral... Granted I'm weaning off of Zoloft as well so who knows but I find with medications with 'weight gain' as a side effect just trying your hardest to eat a well balanced diet will prevent it. It's too easy to give up and say oh well I'm gonna get fat - - it's very much not the case. Don't give up, if you're bipolar like me there's a chance you can do a lot with your brain so give it a shot and take your life back. I think much more clearly and am more productive. The overwhelming tiredness subsided after one week."

   
9.0

Patient 2545865 (taken for 1 to 6 months) April 29, 2017

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For Bipolar Disorder "I have Bipolar, most the time being on Seroquel has helped settle my racing thoughts, helps me sleep at night, and helps me regulate my moods. At times I still get the highs and lows but not as severe without Seroquel. The side effects that I get is dry mouth, dry skin, increased appetite and High Cholestrol. Most of the time this medication helps me out."

   
8.0

AlouiseH April 20, 2017

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For Bipolar Disorder "I take this medication for bipolar, but it also does wonders for generalized anxiety disorder. I have suffered for DECADES with anxiety and panic attacks and SSRIs have stopped working for me. When I started taking seroquel it was like I finally saw color in the black and white world I was living in. My moods are completely under control and my anxiety is controlled for the most part. This medication definitely has side effects. Its a tranquilizer. It makes you very tired. It also made me gain a significant amount of weight...but I would rather deal with the side effects then deal with the horrible anxiety I was living with everyday. I take it before bed...make sure you're able to get at least 8 hours of sleep so you're not groggy the next day"

   
9.0

Anonymous April 11, 2017

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For Bipolar Disorder "I have been on this for about 2 months and I've recently been getting extremely tired all day long (even if I take it way earlier the day before). The drowsiness is so extreme that I cant even watch a show. I'm literally struggling to stay awake all day cause I feel like I just wanna sleep my life away. My depression has been through the roof as well! And to top it off, the weight I have gained since I have been on it, has been insane. I constantly wanna eat all the time! I have gained at least 20-30 pounds in the past month or two! I am definitely gonna tell my doctor I want off of it ASAP! I cant take it anymore "

   
1.0

Brittiany April 5, 2017

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For Bipolar Disorder "I'm 24 yrs old, have severe RA and been talking seroquel XR at 300 milligrams a night for nearly a year.... I was diagnosed bipolar 2 years ago but had so much trouble finding a psychiatrist who was caring enough to listen to me (like a psychologist AND work as a psychiatrist, pill pusher) so my diagnosis went treated and untreated on and off for a while. BUT since I've been seeing my doctor regularly and she seems to genuinely care I've trusted her judgment with her diagnosis and what she thought would help me most.... besides the weight gain, honestly I feel much more stable & I can deal with the world around me as I see it and haven't had any serious depressive episodes or hypomania. This medication has worked wonders for me."

   
9.0

Nessa Rea March 15, 2017

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For Bipolar Disorder "No dude it doesn't work. I've been on it for few months. No it doesn't work for anxiety. It helps the shaking part. That's it. Doesn't work for depression either. When I was on it I hurt myself and was thinking about suicide. It didn't stop my racing thought. My OCD is the same. Man just no. I gained 40 pounds in 2 months just with 250mg. It's the worst medication of its category. I was on Zyprexa before but besides the horrible weight gain at least I was doing much better. I hate this medication. Do not take it people. It makes you fat doesn't help at all. No man just NOOO. I'm going back to Paxil 30mg and Zyprexa 7.5 mg which work so much better. Bye SEROQUEL."

   
1.0

Joj (taken for 1 to 6 months) February 3, 2017

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For Depression "I have depression with anxious disitress.My extremely racing thoughts would typically whip me up into a panicky state, sometimes with outbursts of irrational anger. Seroquel XR works fantastically to ease that racing mind, to a more 'normal'and useful pace. Side effects are virtually absent: the XR doesn't floor me like immediate release Seroquel did. I can function and think well. Seroquel XR is a good medicine. It also helps with my depression."

   
10

Global Man January 25, 2017

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For Major Depressive Disorder "been great for me except for the weight gain , I just want to eat all the time"

   
9.0

Shazza Hall October 23, 2016

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For Schizoaffective Disorder "Hi I'm taking seroquel XR 400mg.it all started last winter with my psychosis episode. I went a bit manic,anexity,depression.wont get into details. I went in mental hospital for 2 months,there is where i started taking seroquel. to be honest 1st 2 weeks i have been vomiting every single night,had dizzines so hard that I had to hold walls while walking down the hallway.Its fine because at that point I didn't know if its just a bad dream or reality.after period of let's say 2 months I got much better.still i was feeling like my emotions, vocabularity, thought's was really in bad condition. as time passes I got used to it (im using it for 10months now.) DONT DO COLD TURKEY!!!"

   
8.0

sin47 (taken for 6 months to 1 year) October 23, 2016

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For Bipolar Disorder "My diagnosis is Bipolar one. I have been on Serequel XR for 3 years now. I have been stable for one year which is amazing. I am very lucky that this medication works really well for me. For the first few months or so it increased my appetite and I was fairly sedated throughout the day. As I adjusted to the medication this wore off. I now function better than I ever have. Suicidal thoughts are pretty much all gone, and when they do come, they pass. Have not had any depression, and only slightly concerning elevated moods (which happen rarely.) This drug prevents me from psychosis and for that I am extremely thankful. I am on 600mg once at night. UK resident."

   
10

ThimbleCat October 13, 2016

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For Depression "I am diagnosed with borderline personality disorder with psychotic features. I was put in intensive out patient care after going to the Emergency Room for intense auditory hallucinations that were so malicious I feared for my own life. Lost my job and everything. Seroquel has given me hope as well as lorazepam for my anxiety. To me seroquel is a miracle drug for its antipsychotic features as well as depression. I'm having to up the dosage lately because my voices are creeping back in. Searching for further pychiactric help but right now I'm stable and I thought that would be impossible. Sharing a good experience. Thanks for reading."

   
9.0

Keylimeisbomb (taken for 1 to 6 months) October 5, 2016

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For Bipolar Disorder "Have been on Seroquel XR 25mg (once before bed) for about 6 months now and my life has completely changed for the better. Yeah, the weight gain is a pain but its a small price to pay for normality. Social anxiety / severe insomnia has not been an issue for months!! Am finally myself again. Have tried other antipsychotics but nothing works as well as this one. Only downside is an insatiable appetite - but you can minimize weight gain by substituting with fruits etc, which is what Im currently doing."

   
8.0

vanillacoke (taken for 1 to 6 months) September 13, 2016

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For Major Depressive Disorder "1200mg xr per day worked and stopped my mental process enough to pave the road to recovery. I developed arthritis in both hands and the most savage ADDICTION ever known to man i was now facing. I have now stopped compleatly and all the words and reviews can never prepare you for such an experience. I took the cold turky approach and 3 months of violent withdrawls i have stayed clear. I WOULD RECOMMEND OTHER TREATMENTS BEFORE THIS AS A LAST RESORT. It saved my life but at what cost. I still have mental health issues amd arthritis but i quickly get on with my day when i realise i could be back taking them."

   
2.0

Dave's truth.. (taken for 1 to 2 years) September 9, 2016

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For Bipolar Disorder "This med is pretty wonderful for my bipolar mania and my bipolar depression. Only set back is the sedation, but at the same time I've always struggled with anciety, so this side effect is okay with me as it helps the anxiety. Really saved my life."

   
10

AngelBunny0316 (taken for 6 months to 1 year) August 23, 2016

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For Depression "I have only been on Seroquel XR for about a week at 50mg. My doctor prescribed it as an adjunct to Remeron to treat anxiety, depression, paranoia, and insomnia. I also take gabapentin, atenolol, and Xanax. When the Seroquel XR works, it WORKS. I can feel it sedating me two hours after I take it. I've been sleeping eight and nine hours a night, which has not happened in a very, very long time. It's effective at neutralizing both anxiety and depression. BUT... it doesn't last 24 hours for me; it only lasts about 15. Once it wears off my anxiety and depression return with a vengeance. Makes for a very rough 8 or 9 hours until I can take it again."

   
6.0

This is Kris (taken for less than 1 month) August 15, 2016

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For Bipolar Disorder "First of all, let me start by saying that I hear that this is an expensive drug because of how new it is. Luckily for me (perhaps, lol), my insurance considera me catastrophic due to my checkered past, and pays the entire price because they want me to take this medication and stfu lol. Since taking Seroquel XR, my life has improved so much, and I really have never felt more stable in my life. I've tried anticonvulsants and other antipsychotics and they have not worked for me. This medication really does, to my surprise! The only downfall is that I've gained 10 pounds taking it, but any antipsychotic will do that. Strongly recommend Seroquel XR!"

   
10

JoeyBBY92 July 16, 2016

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For Bipolar Disorder "I really noticed a negative difference when comparing the XR version to the regular Seroquel. It took longer to kick in and made me so drowsy at work that I felt like I was drunk. I think I was taking 100-200 mg. When I went back to regular Seroquel, 100-200 mg put me to sleep fast and made a difference in stabilizing my mood without me feeling too drowsy to function the next day."

   
4.0

Anonymous June 6, 2016

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For Depression "I've been on just about every antidepressant on the market and my doctor and I decided to try adjunct therapy with Seroquel to "boost" the effect of the Brintellix I take. I was really pleased to find it has a significant effect on my anxiety, which has always been a major component of my depression. While it didn't get rid of my depression, I feel better overall than I have in ages. Downsides? It's expensive if you don't have good insurance. I get a 90-day supply for $80. It also will knock you the heck out. I have to take mine before 6 p.m. or I will have great difficulty in waking up (even with an alarm). It has a heavy sedating effect."

   
8.0

garybooberry (taken for 1 to 6 months) May 10, 2016

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For Schizoaffective Disorder "Been on regular seroquel for 4 years fine. Started this for mania/depression and paranoid thoughts. Awful. Weaned up from 50mg to 450mg then back down to off in 1 week. Stomach pains. Out of touch with reality. Groggy. Weight gain immediatley. It helped the symptoms, but no way to live."

   
1.0

Jt131.31 April 27, 2016

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For Bipolar Disorder "I was prescribed seroquel xr for Bipolar depression My dr started me on 50mg and I am gradually increasing the dosage its been about 4 weeks and I am currently taking 200 mg I will agree that it has helped the hopelesness feelings and suicidal thoughts Which is a plus but the zombie like feeling and dry mouth are tough I have a job that requires constant activity its hard to keep up have to definitely slow down My Dr advised me that these side affects are all normal and eventually I will get used to it can't wait for this to happen"

   
7.0

shortie62 April 9, 2016

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For Depression "It was mainly prescribed as a sleep aid, in addition to its antidepressant qualities. I was on regular Seroquel and now on XL as I have trouble staying asleep. It's slightly better. I'm getting 6 hours of sleep a night. I am not usually groggy or snowed by this, maybe once per 30 doses. I'm ok with it. Only downside is cost (XL is brand)"

   
8.0

Anonymous (taken for 1 to 6 months) March 30, 2016

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For Bipolar Disorder "Been on Quetiapine MR for around 9 months. 300mg at night. Found it far less sedating than Olanzapine. Its been a miracle for my Bipolar, absolutely no depression and no manic episodes. Yeah I put on weight but the effects on my mood and mental health have been incredible."

   
9.0

p-mo (taken for 6 months to 1 year) March 23, 2016

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