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Seroquel XR User Reviews & Ratings (Page 3)

Seroquel XR has an average rating of 7.1 out of 10 from a total of 205 reviews on Drugs.com. 62% of reviewers reported a positive experience, while 19% reported a negative experience.

Reviews for Seroquel XR

  • lynnpl
  • Taken for less than 1 month
  • December 29, 2012

For Bipolar Disorder "I've been in and out of mental health clinics for a long time..just trying to find something to slow my racing thoughts and make me feel like life is bearable. I've taken benzodiazepines..only to become drug seeking and take too many and need early refils, thereby being forced by prescriber to wean off. Done SSRI's with no effect whatsoever. Remeron made me gain 40 pounds in like 2 months time and didn't help me sleep. Marijuana made me paranoid. I just started some new therapy and was diagnosed with bipolar 2 and post traumatic stress disorder. She gave me Seroquel XR and my mind is calm and I sleep good on it. I'm still on a pretty low dose..going up to 100mg tonight and then 150mg on 2 days. Just hope I don't gain weight but so far I feel productive and my mind is quiet."

8 / 10
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49 Report
  • sick...
  • Taken for 1 to 6 months
  • August 26, 2015

For Depression "Hate this med. Constantly sick on it. Stomach pain, severe diarrhea, passing out, severe dizziness and unable to wake up. Hungry for food all the time. Nasty taste in mouth. Thirsty all the time. Can't motivate myself to do anything. This was on the lowest dose available. Won't take it ever again don't care what my doctor says. No way."

1 / 10
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40 Report
  • Natty...
  • Taken for 5 to 10 years
  • March 8, 2013

For Bipolar Disorder "I was diagnosed with bipolar II about 5 yrs ago and I've tried everything on the market nothing worked for me except Seroquel. Right now I take 300 mg twice per day and I'm so stable. I'm loving it problem though with Seroquel is that its a major weight gainer. I would stop taking it on and off when I felt better but then would use other meds to bandage my symptoms...get back on then off again...until one day I decided to stop with the denial and allow someone to help me for real. I've been on it now faithfully for 9 months...but I've put on 60lbs! It makes me eat after hours in the middle of the night. I'm depressed because of the weight gain. So I workout at home at times trying to be more consistent. You have to work this medicine."

10 / 10
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47 Report

Frequently asked questions

  • Joj
  • Taken for 1 to 6 months
  • February 3, 2017

For Bipolar Disorder "No dude it doesn't work. I've been on it for few months. No it doesn't work for anxiety. It helps the shaking part. That's it. Doesn't work for depression either. When I was on it I hurt myself and was thinking about suicide. It didn't stop my racing thought. My OCD is the same. Man just no. I gained 40 pounds in 2 months just with 250mg. It's the worst medication of its category. I was on Zyprexa before but besides the horrible weight gain at least I was doing much better. I hate this medication. Do not take it people. It makes you fat doesn't help at all. No man just NOOO. I'm going back to Paxil 30mg and Zyprexa 7.5 mg which work so much better. Bye SEROQUEL."

1 / 10
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33 Report
  • cano
  • Taken for 1 to 6 months
  • February 14, 2021

For Bipolar Disorder "I’ve been on it for about a month to treat my Bipolar Disorder at a very low dose. It’s worked WONDERS. I genuinely feel for the first time in my life “well adjusted”. I’m much less anxious and when I am anxious it’s just for a short time, not the entire day or days at a time. I also sleep much more soundly, am less susceptible to becoming overwhelmed by small tasks, my thoughts are generally more pleasant (there still are rough moments and intrusive thoughts, just less often now), and have had more “good” days in the past month than in the whole past 3 years. My only side effect has been dry mouth."

9 / 10
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18 Report

Are you taking this medicine?

  • Chris
  • Taken for 2 to 5 years
  • October 5, 2013

For Schizophrenia "From the age of eleven to seventeen, I lost touch to reality, no doctor could figure out what was wrong with me cause I didn't tell my real problems. I was living in an imaginary world. At the age of seventeen I was finally able to express some of my problems, and got started on Seroquel XR, day by day I had the feeling of becoming normal again, and regained the control over my own life. I still have issues from all the problems that involved my past, but I can truly say that I got control back. I truly think Seroquel XR saved my life."

9 / 10
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44 Report
  • Music...
  • August 17, 2017

For Bipolar Disorder "I have been taking this drug for a year and a half and it has changed my life. I've tried various drugs and lifestyle treatments over 5 years of great instability and desperation, going between breakdown after breakdown. Finding the right dose and preparation (slow release) has not only lifted me from crisis, but improved my wellbeing to an all time level. (It took a little while to adjust.) In particular it guarantees me a good night sleep and I can up the dose slightly if things slip. It has done wonders for my anxiety and given me the stability to really be what I want to be. I feel it is important to note that the drug is one part of the picture, and mindfulness, exercise, social/professional support etc. are important where possible"

10 / 10
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31 Report
  • pjsy
  • October 31, 2011

For Bipolar Disorder "The Seroquel makes me feel like I'm dreaming. I kind of feel like I'm losing my sense of reality. The dreams/nightmares I have seem lucid like I can't tell the difference between what I dreamt and what really happened. It is just completely changing my personality. I don't feel like myself anymore."

4 / 10
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48 Report
  • The...
  • March 15, 2014

For Bipolar Disorder "Aching or discomfort in the lower legs or sensation of crawling in the legs, unusual tiredness or weakness, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, muscle pain or cramps."

7 / 10
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41 Report
  • Tom...
  • Taken for 2 to 5 years
  • January 29, 2018

For Depression "First, I'm not schizophrenic, nor have I been diagnosed as bipolar.. I take this for drug induced anxiety I was initially given Seroquel XR because I exhibited rapid speech & a disorganized thought pattern during my (continual) intoxication by kratom. Kratom is a 'natural', legal substance with opioid and stimulant qualities. Well, I noticed right off that Seroquel XR calmed my racing thoughts. I saw this as a benefit -- but the next move was for me to quit using kratom. I got help for that via SUBOXONE, which I'm still on. My whole life & way of thinking took a sharp turn for the better. I remain on the Seroquel XR, along with the SUBOXONE. When I questioned the continued need for Seroquel XR, my Dr. simply said, "Look, you're doing great. Why change a thing?" And he's right. So Seroquel XR remains a part of my daily recipe for success."

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28 Report
  • DETER...
  • April 26, 2010

For Bipolar Disorder "I was diagnosed Bipolar 1 with psychotic features 3 years ago, but always dealt with grandiose thinking, mild delusions, a good deal of depression. After self medicating for two years I had a mental melt down and after spending 2 months cooped up in my apartment, anorexic, dying; I decided it was time to see a psychiatrist. The medications I was prescribed ranged from mood stabilizers to antipsychotics, benzo's, sleeping pills, many I was allergic to like Depakote and Trileptal. Anyway at first I tried the regular Seroquel but gained 40lbs in one month and slept 14 hours a day. Switched to Seroquel XR, not as tired, lost 20bs, appetite/ mental noise decreased, panic relief, strong sleep aide, life manageable, they are expensive. HIGHLY recommend."

9 / 10
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51 Report
  • Angry...
  • April 11, 2012

For Depression "Was taken off Geodon because of night-time anxiety and put on Seroquel XR. I feel so unmotivated. Sedated. I no more feel better by afternoon when it's time to take it again. I dread the next dose. Haven't felt this depressed in a while."

1 / 10
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46 Report
  • Belin...
  • Taken for 1 to 6 months
  • December 22, 2015

For Major Depressive Disorder "Absolutely amazing drug. Has quite literally saved my life. Pity I need to lie to the Australian government about having bipolar to get it prescribed. No doubt this is stopping many thousands of Australians from getting access to it. Seriously. I went from suicidal for several months to absolutely normal in one dose. One dose. Talk to your doctor about this if anti depressants are not working for you. Understand it may require you to lie about having bipolar."

10 / 10
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34 Report
  • maybe...
  • May 9, 2013

For Bipolar Disorder "I take this medication for Bipolar II and it has been amazing at stabilizing my moods. I no longer feel filled with rage and irritability and no longer have issues with impulsive thoughts. The big problem that I am having with this medication is horrendous weight gain. I exercise at least three times a week and eat well, yet I have gained 20kg (44.09 pounds) in the 8 months that I have been on this medicine. Another issue I have is vivid dreams. But I think this is just a sign of getting deep and sound sleep - something I could never achieve prior to taking this medicine. It is amazing but a nightmare all rolled into one."

7 / 10
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41 Report
  • AlexisM
  • November 6, 2017

For Depression "I've been on this for 4-5 years and it is my rock. It literally helps me so much, I couldn't have made it through high school without it. Honestly it's what helped me through my suicidal phases. I still get them but it's not as intense and I don't try and act on it anymore."

10 / 10
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27 Report
  • Britt...
  • April 5, 2017

For Bipolar Disorder "I have been on this for about 2 months and I've recently been getting extremely tired all day long (even if I take it way earlier the day before). The drowsiness is so extreme that I cant even watch a show. I'm literally struggling to stay awake all day cause I feel like I just wanna sleep my life away. My depression has been through the roof as well! And to top it off, the weight I have gained since I have been on it, has been insane. I constantly wanna eat all the time! I have gained at least 20-30 pounds in the past month or two! I am definitely gonna tell my doctor I want off of it ASAP! I cant take it anymore "

1 / 10
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29 Report
  • Jenne...
  • Taken for less than 1 month
  • March 12, 2016

For Bipolar Disorder "OK, it's only early days, day 4 to be exact on 50mg morning and night. It's amazing! After reading all the horror stories of the tranquilliser effects, zombie like states+cravings. Its an understatement when I said I was petrified what effect this would have on me. First day within an hour of taking it, I slept for six hours woke up feeling fine, refreshed even. Then dosed up in the evening at 9, again, asleep by 11, slept like a baby. 7am Woke feeling energised, lighter, happier. No drowsiness or brain fuzz! I feel so much more positive about life in general. I feel so blissfully normal! Day 4 still napping within 4 hrs of dose for 2 hrs max but I could push through it. And still sleeping all night!"

10 / 10
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  • Thimb...
  • October 13, 2016

For Bipolar Disorder "My diagnosis is Bipolar one. I have been on Serequel XR for 3 years now. I have been stable for one year which is amazing. I am very lucky that this medication works really well for me. For the first few months or so it increased my appetite and I was fairly sedated throughout the day. As I adjusted to the medication this wore off. I now function better than I ever have. Suicidal thoughts are pretty much all gone, and when they do come, they pass. Have not had any depression, and only slightly concerning elevated moods (which happen rarely.) This drug prevents me from psychosis and for that I am extremely thankful. I am on 600mg once at night. UK resident."

10 / 10
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30 Report
  • happy...
  • Taken for 5 to 10 years
  • November 10, 2013

For Bipolar Disorder "I took regular Seroquel which did help somewhat. I would rate that at a 4 out 10. I found about Seroquel XR when people told me to see a pdoc this was in 2007 because I was bipolar 1 and couldn't get it under control on my first visit with pdoc I told her my situation and Seroquel after my visit she gave me 2 samples of Seroquel XR which was only out 4 months at that time it has been a huge help with mania and depression I take 800mgs at bedtime when I wake up I take 400mg Lamictal that helps a great deal for me with the racing thoughts and impulsivity along with 2mg of clonazepam that has been a life saver it took many years in and out the psyc hospitals to finally get it right."

10 / 10
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  • Anonymous
  • November 14, 2009

For Insomnia "I completely support the first review. I have had insomnia for many years and tried everything from herbs to drugs. And only this could help and provide a good rest during the night. I have already taken this medication for over 5 years, about 25mg not more. It is enough to get 8 hours with no dreams sleep !"

9 / 10
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  • Anony...
  • Taken for 1 to 6 months
  • March 30, 2016

For Depression "It was mainly prescribed as a sleep aid, in addition to its antidepressant qualities. I was on regular Seroquel and now on XL as I have trouble staying asleep. It's slightly better. I'm getting 6 hours of sleep a night. I am not usually groggy or snowed by this, maybe once per 30 doses. I'm ok with it. Only downside is cost (XL is brand)"

8 / 10
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31 Report
  • JoeyBBY
  • July 16, 2016

For Bipolar Disorder "First of all, let me start by saying that I hear that this is an expensive drug because of how new it is. Luckily for me (perhaps, lol), my insurance considera me catastrophic due to my checkered past, and pays the entire price because they want me to take this medication and stfu lol. Since taking Seroquel XR, my life has improved so much, and I really have never felt more stable in my life. I've tried anticonvulsants and other antipsychotics and they have not worked for me. This medication really does, to my surprise! The only downfall is that I've gained 10 pounds taking it, but any antipsychotic will do that. Strongly recommend Seroquel XR!"

10 / 10
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29 Report
  • Angel...
  • Taken for 6 months to 1 year
  • August 23, 2016

For Bipolar Disorder "This med is pretty wonderful for my bipolar mania and my bipolar depression. Only set back is the sedation, but at the same time I've always struggled with anciety, so this side effect is okay with me as it helps the anxiety. Really saved my life."

10 / 10
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  • B303
  • May 13, 2017

For Bipolar Disorder "SeroquelXR has changed my life for the better. I am currently on 400mg once daily. (I also take klonopin before I go to work). For the last 6 months, I have not had to call out sick from work, which was a monthly occurrence before Seroquel. I have not had to take a leave of absence in the last year. I used to have to take 2 six week leaves a year. I feel much more positive about my job and my life in general. It has been a game changer for me. The only down side is the weight gain. It seems to slow your metabolism down and increase your appetite after taking it, making it difficult to loose weight. I am currently not overweight, so the weight gain is a small price to pay. I do have to exercise regularly and watch more carefully what I eat"

9 / 10
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26 Report
  • Phoenix...
  • Taken for 10 years or more
  • July 19, 2021

For Schizophrenia "Seroquel XR saved my life. But, at a heavy price. Numb, zombie like existence, no emotions, flat affect, morbid obesity. It takes hours and multiple cups of coffee to wake up...etc. But it has kept me safe by keeping me out of the psych ward."

9 / 10
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13 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.