Skip to main content

Seroquel XR User Reviews & Ratings (Page 5)

Seroquel XR has an average rating of 7.1 out of 10 from a total of 205 reviews on Drugs.com. 62% of reviewers reported a positive experience, while 19% reported a negative experience.

Reviews for Seroquel XR

  • Amanda
  • July 23, 2015

For Depression "In the beginning I was on 300 mg of seroquel (not extended release) for 3 years. Got pregnant they took me off. I moved provinces they ended up putting me back on a smaller dose 150mg sleeping wise I would go to sleep right away and stay asleep all night. For the past 2 months they decided to put me on 150mg seroquel xl now it takes me hours to fall asleep and I wake up constantly throughout the night and have a hard time falling back asleep! I feel like xl does not work near as good depression wise and sleeping wise."

3 / 10
Was this helpful?YesNo
23 Report
  • Obses...
  • October 22, 2009

For Obsessive Compulsive Disorder "Diagnosed with GAD and OCD, more so the mental aspect (the obsessions). On clonazepam, Zoloft 200mg and Seroquel XR 50mg a few hours before bed. I have to say that it feels great and helps me fall asleep, but I still have some anxiety driven dreams. The hours before sleep are wonderful, it really takes you down a level or two. I just wish it lasted 24 hours."

7 / 10
Was this helpful?YesNo
33 Report
  • sloth...
  • Taken for 6 months to 1 year
  • December 2, 2020

For Bipolar Disorder "I have been on Seroquel XR for almost a year now. Started on 150mg then went up to 300mg. Today I started 400mg as my moods are getting very impulsive and I’m getting manic. I’ve been on probably over 25+ medications and this is by far the best. Zyprexa made me gain 60 pounds in 6 months and also made my breasts started leaking a milky substance. All I can say is give it a try. It doesn’t hurt at all. You never know if it will be the life changing medicine for you."

8 / 10
Was this helpful?YesNo
11 Report

Frequently asked questions

  • KoRny...
  • February 3, 2011

For Bipolar Disorder "I had a "nervous breakdown" in November of 2009 and ended up in a psych hospital where I was promptly given Seroquel among other medicines. The Seroquel was amazing. I felt like someone switched the on button in my brain and I finally woke up. When I got out of the hospital and sought out a new psychiatrist for treatment, he took me off of the Seroquel because I am diabetic. After a year of unsuccessful treatment with other medicines, I begged to be put back on the Seroquel because the depression was unbearable, and I wasn't responding to other medicines. So he agreed and once again that switch has been flipped on and I feel "normal"! I am only on 300mg. I have to take it early because it knocks me out. In the morning I am very dizzy and have slurred speech."

10 / 10
Was this helpful?YesNo
30 Report
  • Anonymous
  • September 18, 2011

For Depression "Seroquel XR is very good. It boost up my energy. After trying other medications this is the best with little side effects. In the morning you feel like staying in bed and weight gain because of hunger craving. "

9 / 10
Was this helpful?YesNo
29 Report

Are you taking this medicine?

  • Longh...
  • Taken for 6 months to 1 year
  • November 18, 2017

For Bipolar Disorder "I was taking 300 mg of Seroquel XR for 6 months. The best part was being able to get a good night’s sleep. I had only been getting 2-3 hrs rest each night. My mind would race and it was a struggle to stay in bed. I would get up and start cleaning. Additionally, I would spend hours creating plans to organize my life. I had not actually followed any of those plans and I was depressed. I took Latuda for a short period but it made my inability to sleep worse. That’s when I was switched to Seroquel. I loved the way it helped me feel normal. The bad - I gained 30 lbs in 6 months. I asked to be taken off and started taking Geodon. Once again I cannot sleep. I am going to ask to go back to Seroquel XR and focus on following a healthy diet."

9 / 10
Was this helpful?YesNo
17 Report
  • culle...
  • September 27, 2010

For Bipolar Disorder "After much trial an error with other medications I am pleased to find that Seroquel XR really helps. I take 500 mg per day. Started at 200 but worked my way up until I felt better. Wish I had discovered this years ago."

9 / 10
Was this helpful?YesNo
29 Report
  • Haley...
  • December 28, 2015

For Major Depressive Disorder "I'm currently taking 150mg seroquel XR along with 45mg Remeron for MDD I take them both at night, To help with my sleep. It also is to help my anxiety disorder. I've noticed that I am less depressed and anxious, But that's only because I'm so depersonalised I can't focus on my surroundings, Let alone my anxiety I constantly feel stuck in a dream-like state and I can't focus. Even as I write this I'm struggling to find the words,and describe how I feel, Because I don't feel much of anything I haven't had many other side effects, even when I drastically increased the dose All in all, It technically does help, But this is no way to live"

6 / 10
Was this helpful?YesNo
20 Report
  • Bipol...
  • July 31, 2017

For Bipolar Disorder "I have to say I've this medicine a 7 out of 10 because it has brought me out of both some wicked manias and depressive episodes. The sedation is a love-hate relationship with me- It's nice for my anxiety, but is also a nuisance. I MUST take this medicine 12 hours before I need to wake up, or I have trouble waking up. I feel it does interfere with my creative and intellectual abilities a tad bit. Overall, however, it's good med."

7 / 10
Was this helpful?YesNo
17 Report
  • p-mo
  • Taken for 6 months to 1 year
  • March 23, 2016

For Bipolar Disorder "Been on Quetiapine MR for around 9 months. 300mg at night. Found it far less sedating than Olanzapine. Its been a miracle for my Bipolar, absolutely no depression and no manic episodes. Yeah I put on weight but the effects on my mood and mental health have been incredible."

9 / 10
Was this helpful?YesNo
19 Report
  • baby...
  • June 29, 2009

For Bipolar Disorder "I think this is one of the best medication's out there at this time. It has really changed me 100%. I have bipolar and I can't tell you how happy I am. I have also been on regular Seroquel and there is no comparison XR for me works far better than the regular. "

10 / 10
Was this helpful?YesNo
30 Report
  • SuniS...
  • January 3, 2009

For Bipolar Disorder "I like this medicine. Even the side effects are manageable. I get loopy on them, but that is better than the screaming drama queen I once was. I take 600 mg and have a psychiatrist and a councellor, who that helps me through situations that I used to rage through. Also, I'm a rapid-cycling BiPolar II so I think it's wonderful just to be able to be somewhat normal."

7 / 10
Was this helpful?YesNo
30 Report
  • normal
  • Taken for 5 to 10 years
  • December 9, 2022

For Bipolar Disorder "Five years ago, I was diagnosed with Bipolar 2 Disorder, anxiety, PTSD, breakthrough depression, and ADHD. I never realized I was depressed I thought it was just my life. I did not think I had any of these things, but by the grace of God, I saw a psychiatrist at my recovery clinic, and he sat, he talked with me, and here I am. Seroquel XR has literally saved my life. My mood has never been better. For many years of my life, I was mad at the world or could barely get out of bed. Since taking this medicine, I feel normal for the first time in my entire life. My mental health was a big part of why I self-medicated, and did not realize this until that appointment. I would suggest that if the doctor offers this, it would be wise to try it."

10 / 10
Was this helpful?YesNo
5 Report
  • Anonymous
  • August 18, 2013

For Schizoaffective Disorder "I take this medication for its side effects primarily. It works great if you have severe insomnia. This medicine makes you very hungry when you take it. It also helps to relive anxious feelings and help calm feelings of stress. Again my doctor prescribed this medicine due to weight loss, insomnia, anxiety. This is not what the medicine is exactly made for but I have tried dozens of medicines and this is the only one that has helped with my problems."

9 / 10
Was this helpful?YesNo
23 Report
  • Anonymous
  • May 17, 2010

For Generalized Anxiety Disorder "Excellent for sleep onset - up to a point. If things get really bad, I've had to augment it with temazepam and Valium. I also have depression. I was on and off it for about 3 months and it causes brain fog and word retrieval problems. There is also a significant increase in appetite, but it's not as bad as Remeron."

6 / 10
Was this helpful?YesNo
28 Report
  • Anonymous
  • August 8, 2009

For Bipolar Disorder "Great medication for agitation and sleep when taken in the evening. There is a bit of a hangover period for a couple of hours but that is acceptable to me for a full nights sleep. Much better than regular Seroquel which you better be near a bed soon after taking it. Seroquel XR is much smoother and gives me a chance to adjust to the sedation as I get ready for bed."

9 / 10
Was this helpful?YesNo
29 Report
  • MarkyBy
  • June 21, 2015

For Bipolar Disorder "I went from talking 120mgs of Cymbalta to taking 150 mgs of Seroquel XR just over one year ago. I fortunately did not suffer from any if the initial side effects that I've now researched & have learned are really common when starting this medication. However, 1 month ago, I'm not sure why but I ended up missing 2 nightly doses. What I experienced was nothing short of being in hell, literally. I physically was incapable of movement, getting up to simply get to the restroom was near impossible, every muscle in my body was weak & near useless. I couldn't do anything but remain in a fetal position curled up on my side for the duration of over 12 hours. My head was cloudy, confused & unable to process any thought. After this experience, I want off"

2 / 10
Was this helpful?YesNo
19 Report
  • Anonymous
  • April 11, 2017

For Bipolar Disorder "I take this medication for bipolar, but it also does wonders for generalized anxiety disorder. I have suffered for DECADES with anxiety and panic attacks and SSRIs have stopped working for me. When I started taking seroquel it was like I finally saw color in the black and white world I was living in. My moods are completely under control and my anxiety is controlled for the most part. This medication definitely has side effects. Its a tranquilizer. It makes you very tired. It also made me gain a significant amount of weight...but I would rather deal with the side effects then deal with the horrible anxiety I was living with everyday. I take it before bed...make sure you're able to get at least 8 hours of sleep so you're not groggy the next day"

9 / 10
Was this helpful?YesNo
16 Report
  • Might...
  • January 19, 2016

For Major Depressive Disorder "I'm currently 30 and a male. My depression has only worsened since (and before) my initial diagnosis of depression and generalized, social and "acute" anxiety 13 years ago. I've been in a major depression for at least five years, tried to kill myself twice and am unable to take care of myself. I've lived alone since I left for college in 2003. I still live alone here. I've been on any SSRI I can think of, so this was a last resort med. Seroquel has made me much too tired to work or do anything else. The only stars I gave it relate to the reduced anxiety when I'm ACTUALLY AWAKE. Other than that, I'm more numb than I ever and are at risk of losing my job"

2 / 10
Was this helpful?YesNo
18 Report
  • Ann
  • October 8, 2015

For Bipolar Disorder "I have been taking seroquel for a little over a year and a half now and it has been the best thing for me. I started off at 350mg when my mania was insanely uncontrollable. But after 2 months I was able to go down to 250 and ever since its been perfect because I don't fight the drowsiness in the mornings and get a great nights rest. I did gain weight, only 20 pounds, but I have always been extremely athletic (2 sport collegiate athlete) and it didn't really affect me at all. Just as long as it keeps the manic/depressive episodes on lock down I think I can handle a curvier body. I seriously reccommend this if you can handle a little weight gain!"

10 / 10
Was this helpful?YesNo
18 Report
  • Mil
  • Taken for 1 to 6 months
  • August 13, 2018

"I'm taking Seroquel XR 100mg daily, in the evening, before sleeping, and Flunisann(Fluoxetine hydrochloride) 10mg (antidepressant) in the morning. I'm 30 years old, and have serious anxiety problems over 15 years, with few psychotic breaks, caused by stress and anxiety. I tried a lot of different types of medications over the years, and I always felt miserable and weak while taking medications plus I had some side effects, like weight gain, and I was more or less vegetable. Now, I'm taking Seroquel over 4 months, and I feel like old me again, my work is in creative fields, in which I achieve great results right now. If you watched movie "Limitless", that is my situation right now. Of course I have my low periods at times now too, but I have will and techniques to overcome it quickly. If you are in similar situation, I recommend you to try this therapy. I wish you well, cheers!"

9 / 10
Was this helpful?YesNo
13 Report
  • mrsnowe
  • Taken for 6 months to 1 year
  • January 4, 2016

For Bipolar Disorder "I was on citolopram (celexa), lithium 1250 mg daily and olanzapine 20 mg and a lot of benzos. A state run mental health clinic opened in a local town so I stopped seeing the private psychiatrist and started to attend the public clinic. The psychiatrist was revolutionary. She immediately stopped the anti-depressant because it was elevating mood into mania. She dropped lithium to one dose at night to aid kidney wear and tear. She stopped olanzapine because I was still having mild persistent psychosis and put me on 800mg of quetiapine (seroquel). The first week was tough I was very nauseous and sleepy but once my body adjusted it was much better. The mix of quetiapine and lithium is really working for me."

10 / 10
Was this helpful?YesNo
17 Report
  • Ori
  • Taken for less than 1 month
  • January 19, 2013

For Bipolar Disorder "I was one of the unlucky ones who's prolactin levels skyrocketed. I was only on 100mg, with a plan to ramp my way up to 500 over the course of 10 weeks, which was obviously vetoed when my chest started swelling quite noticeably. Lactation isn't worth what's essentially only a sleeping pill at <500mg doses."

2 / 10
Was this helpful?YesNo
21 Report
  • Theresa
  • Taken for 5 to 10 years
  • February 20, 2024

For Major Depressive Disorder "I was diagnosed with MDD about 6 years ago. After a stay in the psych ward, I was put on Cymbalta, Trazodone, and Seroquel. I didn't realize I could ever feel this good. Just became full and never stop cold turkey."

10 / 10
Was this helpful?YesNo
1 Report
  • Wretc...
  • Taken for 2 to 5 years
  • March 13, 2016

For Major Depressive Disorder "I have suffered from major depression since early adolescence, and have been exposed to over 2 dozen different anti depressants in the last 30 years. Expensive, ineffective, grossly negative side effects to skin and, chronic fatique daily. Trying another high cost drug a desperate last resort. Each dirty little pill failed, with accumulated cost of more than $15,000 to the patient asking for help Negligent dispensation of Seroquel XR also resulted in near fatal car wreck for the patient. Aside from losing my car, and job, I was priveleged to gain 40 pounds, .... and counting. Chronic insomnia kills drivers, truckers, pilots, boat captains every day. Drug companies need try a lot harder to promote healing, rather than just bank roll profits"

2 / 10
Was this helpful?YesNo
16 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.