Seroquel XR for Depression User Reviews

• josia...
• May 25, 2021

"I am diagnosed with BPD, severe anxiety and depression. I've tried multiple antidepressant before, and none of them worked for me. My doctor prescribed me 50 mg of Seroquel XR, and I take it before going to sleep. I have now been taking it for 3 months, and it literally saved my life. I've experienced some side effects at first, but now that my body is used to the medication, I feel so much better. I can go out, see friends, and do a lot of things I couldn't even think about doing 2 months ago. In contrary to a lot of people, I didn't gain weight yet, I even lost some. It also helps my mood swings and my dissociation. The only negative thing I can think of is the tiredness. But, if I get out of bed right away, I'm good for the day. I can recommend to not take it too late, because it can make it hard to wake up in the morning. In conclusion, I think it's a great medication and even if you're scared to take it, just give it a try and let it time to start working."

• sarra...
• Taken for less than 1 month
• June 14, 2014

"I have only been on Seroquel 25 mg for just over a week. So I cannot say if I will experience the weight gain or not. But so far this is the best thing that's worked for me. I was horrifically depressed and anxious for over a year, and before that moderately. But after just 1 days on the Seroquel I felt a huge difference. My thoughts had slowed down, my anxiety and depression got cut in half, my appreciation of time and continuity came back a bit, the disassociation was appeased. For the past year I felt like I was on one giant bad paranoia trip, and only after I started taking this medicine did I feeling normal again. There are still major things that are a problem, but the Seroquel makes it way more manageable."

• cdfig
• February 20, 2015

"Seroquel XR worked very well for me with a combination of Seroquel and Zoloft together. I've been well for over 3 years now. Usually I would fall in to a depression with in a year just taking an antidepressent Because my body would build a tolerance to the medications. I know this medicine isn't for everyone, but I've had a very good experience and I'm stable and happy."

• Wanna...
• February 7, 2014

"I am presently in hospital and have been put on Seroquel XR. As previously commented, the low dosages cause lethargy and sleepiness. However, I am not nearly as suicidal as I was, I have hope for the future and have not been on for more than a few days. I am optimistic that once I have reached the proper dosage that I will once again enjoy life as I once did. Paxil, Effexor and a number of other antidepressants worsened by symptoms over time and/or never did do much for the depressive symptoms in the first place. This medicine is worth trying if you are extremely depressed or suicidal."

• TOC...
• Taken for 1 to 6 months
• May 30, 2013

"After taking Seroquel for 5 months at 25 mg, I recently upped it to 50 mg at night-time. This has resulted in me being able to drop my Ativian from 2 mg to 1 mg and still get a great sleep. I am much more productive, think clearly and feel positive. I feel like my personality is coming back. Coincidence? I think not."

• Anonymous
• February 2, 2012

"I've had depression since I was a young teenager. I didn't decide to get treatment until I was 24. I felt like I was unraveling. I didn't want to get out of bed. I lost interest in all the things that I once loved to do. I had problems with drugs and alcohol. Sleeping problems. The whole nine yards. The medication that my doctor decided to put me on was Seroquel XR. I was a little apprehensive at first, being a drug user for many years, I knew what Seroquel was. My doctor assured me that in a controlled and carefully watched environment, she believed it would help. She started me on 50 mgs. I've moved to 150 mgs. I've had drastic positive changes in my mood. I feel happy, rested, and content. No negative side effects. It worked miracles."

• Anonymous
• May 26, 2011

"Seroquel XR has changed my life. I feel I am present again in my world. Before taking this medication I had very little hope that I would ever feel enthusiastic about life. I recognize myself again. I can't say enough about how excited I am about living. I tried so many therapies and had given up hope anything would work. The combination of my antidepressant and Seroquel XR was the key for me."

• Anonymous
• Taken for 6 months to 1 year
• June 6, 2013

"I have had depression since I was a child but I didn't start getting help for it until I was 19. I have tried Prozac and Celexa which did nothing for me and then my doctor asked me if I have ever heard of a medicine called Seroquel XR. I started out on 50mg and then worked my way up to 300mg. The only side effects for me were weight gain and drowsiness but the drowsiness went away after a couple of months of using this medicine. Overall I really like this medicine. It has helped me tremendously!"

• shell...
• November 14, 2013

"I have used this for years now! I love it, before taking I absolutely could not sleep. I started out with 50mg, and am now taking 75mg after all of these years. I cannot sleep without it and I have no side effects from this medicine. "

• Anonymous
• June 2, 2011

"Read a lot of bad things about Seroquel on the web. After a couple days tried it myself (100 mg a night) and I've found it amazing. It really helps with my anxiety and my hyperactive behavior. Just feel a lot more calm and settled in general. Don't believe everything you read. Just try it for a few nights and see how it suits you. Everyone is different."

• Anonymous
• Taken for 1 to 6 months
• January 5, 2014

"Made me a zombie at low doses and didn't help with depression. In fact, I felt even more depressed since I wasn't able to hold a conversation or think straight due to drowsiness.But it seems to work for some people."

• robbi...
• Taken for 5 to 10 years
• December 24, 2015

"I've been on Venlafaxine 300mg along with Quetiapine, Mirtazapine and Pregabalin for Major Depression for around 7 years.Augmentation therapy works for me. It's not perfect, but this level of Venlafaxine along with the other meds has kept me alive. I'm not getting better, but I'm certainly more stable and not going downhill and not suicidal. So in conclusion, don't be scared of meds, they may just save your life."

• Kmtdstr
• Taken for 2 to 5 years
• October 2, 2015

"I have taken it for PTSD at night for a long time. I'm able to sleep without having horrific nightmares. There is weight gain, but that boosts me to eat healthy and exercise, which helps my depression! klonipin to help with daytime anxiety and Seroquel before bed are the two drugs that keep me sane and able to live a normal life."

• mik
• Taken for 6 months to 1 year
• June 17, 2018

"After being hospitalized twice for suicidal ideation, my psychiatrist decided to put me on Effexor and 150mg of seroquel. I was in the hospital while I started the medication, but at the beginning all I could do was sleep for a few days or so. I wasn’t affected by that too much because I was inpatient, but I read some others mentioning this and I can imagine it would definitely get in the way of trying to go about your everyday. Also my mouth was so dry and I lost my appetite (among other symptoms that I don’t really remember). Those symptoms, while very debilitating, subsided within a few weeks though and now I’m much better and I honestly rarely if ever feel depressed any more! I was very reluctant to go on medication but it’s kept me alive so I guess I can’t really hate it that much. This drug, while causing a lot of problems in the beginning, turned out to be a life saver (literally)."

• Sympt...
• January 31, 2011

"I recently started Seroquel 50 MG for the first couple days and then up to 150 MG. This medication works great! It creates anxiolytic effects similar to Klonopin and relieves all my anxiety. I sleep well to. This medicine really knocks you out and makes you very sedated. Take at night. I can actually function thanks to this medication and it works excellently for paranoia, anxiety and depression also found it to work greatly for sleep. I was previously on Abilify which was very activating and gave me a lot of anxiety and I couldn't sleep more than 1-2 hours. On Seroquel I sleep a full 8 hours and I wake up refreshed and ready for the day. It controls my anxiety and works wonders. Side effects are: No sex drive and drowsiness."

• KassR
• July 28, 2008

"Everyday I was very depressed or very angery for no apparant reason. It felt like my brain was all tangled and it was really hurting me, and had been for years. So I talked with my doctor, and she put me on 200mg seroquel. Since then I can think clearly and feel happy, I love it. You start at 25mg and work up to higher doses. Watch out though, if you try to start at 200mg it can knock you out for 24hrs, or at least it knocked me out."

• Issy
• November 10, 2015

"I was diagnosed with bipolar disorder 8 months ago (i am 19) but I do not have that. Instead I have BPD and depression. I was taking olanzapine which took away my entire life - I could barely do anything, but for the past 2 days with seroquel it has almost the opposite effect. Together with Prozac I have felt more motivated and less suicidal. Also I'm able to control my anxiety and I have more control over my behaviour. I also have trouble focusing but this has helped me focus on therapy a lot more. Sleep not great but I'm only on 25mg ; I only sleep for about 6-7 hours and then wake up and keep going back to sleep. This is the first drug that's given me hope."

• Kooshs...
• Taken for 6 months to 1 year
• November 20, 2013

"I have had Bipolar Disorder/Personality Disorder and severe depression for about 30 years and have tried just about every medicine there is. A recent set-back had me in hospital: my Dr. decided to put me on Seroquel XR 400 mg along with my other medicines. In the beginning it seemed to help me, as time went on my symptoms of low mood suicidal thoughts, etc. came back...most important to note was the WEIGHT GAIN. In under a year almost 50 lbs for no real reason. Extreme fatigue and sleepiness-hard to get out of bed in the mornings! Am now reducing dosage to slowly get off it as per Dr.'s orders and switching to an alternative. I am hoping this will work."

• Mikfr
• November 28, 2014

"I was prescribed seroquel 100mg for Post Traumatic Stress Disorder and I could only take it for two days. I took it as prescribed before bedtime. I almost crashed my truck several times on my way to work and I had to pull over on the shoulder to sleep on my way home from work. Day 2 was a Saturday. I slept for 14.5 hours. I can't function at all on this."

• Smittyz
• August 18, 2008

"For years I suffered from severe depression, doctors must have tried every different medicine of this nature in hopes to help me, however it wasn't until I was given seroquel that I began to feel better, and sleep like a baby. At first I would sleep 12 to 14 hours after taking the medicine, then I began to get used to it. I haven't had a bout of depression in 3 years. I can sleep again but now around 8 hours a night. I can honestly say I love this pill. Even with the side effects of hunger it's totally worth it. "

• Global...
• January 25, 2017

"I have depression with anxious disitress.My extremely racing thoughts would typically whip me up into a panicky state, sometimes with outbursts of irrational anger. Seroquel XR works fantastically to ease that racing mind, to a more 'normal'and useful pace. Side effects are virtually absent: the XR doesn't floor me like immediate release Seroquel did. I can function and think well. Seroquel XR is a good medicine. It also helps with my depression."

• This...
• Taken for less than 1 month
• August 15, 2016

"I have only been on Seroquel XR for about a week at 50mg. My doctor prescribed it as an adjunct to Remeron to treat anxiety, depression, paranoia, and insomnia. I also take gabapentin, atenolol, and Xanax. When the Seroquel XR works, it WORKS. I can feel it sedating me two hours after I take it. I've been sleeping eight and nine hours a night, which has not happened in a very, very long time. It's effective at neutralizing both anxiety and depression. BUT... it doesn't last 24 hours for me; it only lasts about 15. Once it wears off my anxiety and depression return with a vengeance. Makes for a very rough 8 or 9 hours until I can take it again."

• garyb...
• Taken for 1 to 6 months
• May 10, 2016

"I've been on just about every antidepressant on the market and my doctor and I decided to try adjunct therapy with Seroquel to "boost" the effect of the Brintellix I take. I was really pleased to find it has a significant effect on my anxiety, which has always been a major component of my depression. While it didn't get rid of my depression, I feel better overall than I have in ages. Downsides? It's expensive if you don't have good insurance. I get a 90-day supply for $80. It also will knock you the heck out. I have to take mine before 6 p.m. or I will have great difficulty in waking up (even with an alarm). It has a heavy sedating effect."

• Arri
• Taken for 1 to 6 months
• November 11, 2015

"My experience on Seroquel nearly cost me my job as it turned me into a ZOMBIE!. Since going off the drug I am fully functional. My head is clear and I have energy to do things. I cannot believe my Dr prescribed me an antipsychotic drug such as seroquel. Colleagues observing me thought I had undergone a major personality disorder. I have been off it for a month now and not missing it one bit."

• Midni...
• Taken for less than 1 month
• April 23, 2013

"I have been on a few antidepressants for 11 years with only fair results. My Doctor started me on some Seroquel XR 200mg at bedtime over the last few weeks. This medication not only has helped me with the terrible side effects when you come off many of the typical SSRI but I am sleeping and my depression has improved from a 2 out of 10 to 7 out of ten. Sometimes, SSRI medication side effects are stated as minor but they can be very severe at times. More Doctors should know about Seroquel XR and the great results when stopping antidepressants."