User Reviews for Seroquel XR
The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Learn more about Seroquel XR.
Reviews for Seroquel XR to treat Depression
"I was on this medication for around 3 years at different doses, anywhere from 50 mgs to 600 mgs. It was a very good medicine and helped a lot with my anxiety and depression and really calmed me down and was very helpful, but the weight gain was a killer. I would try to go off over and over and would have to keep going back to it because I would be in such bad shape without it. I had a love/hate relationship with it. I became pre-diabetic while on it. I finally was able to go off and stay off at one point. It's a great drug, but the side effects are horrible as far as weight gain."
Gastroparesis Girl (taken for 2 to 5 years) May 20, 2017
3 users found this comment helpful.
"I have depression with anxious disitress.My extremely racing thoughts would typically whip me up into a panicky state, sometimes with outbursts of irrational anger. Seroquel XR works fantastically to ease that racing mind, to a more 'normal'and useful pace. Side effects are virtually absent: the XR doesn't floor me like immediate release Seroquel did. I can function and think well. Seroquel XR is a good medicine. It also helps with my depression."
Global Man January 25, 2017
22 users found this comment helpful.
"I am diagnosed with borderline personality disorder with psychotic features. I was put in intensive out patient care after going to the Emergency Room for intense auditory hallucinations that were so malicious I feared for my own life. Lost my job and everything. Seroquel has given me hope as well as lorazepam for my anxiety. To me seroquel is a miracle drug for its antipsychotic features as well as depression. I'm having to up the dosage lately because my voices are creeping back in. Searching for further pychiactric help but right now I'm stable and I thought that would be impossible. Sharing a good experience. Thanks for reading."
Keylimeisbomb (taken for 1 to 6 months) October 5, 2016
39 users found this comment helpful.
"I have only been on Seroquel XR for about a week at 50mg. My doctor prescribed it as an adjunct to Remeron to treat anxiety, depression, paranoia, and insomnia. I also take gabapentin, atenolol, and Xanax. When the Seroquel XR works, it WORKS. I can feel it sedating me two hours after I take it. I've been sleeping eight and nine hours a night, which has not happened in a very, very long time. It's effective at neutralizing both anxiety and depression. BUT... it doesn't last 24 hours for me; it only lasts about 15. Once it wears off my anxiety and depression return with a vengeance. Makes for a very rough 8 or 9 hours until I can take it again."
This is Kris (taken for less than 1 month) August 15, 2016
33 users found this comment helpful.
"I've been on just about every antidepressant on the market and my doctor and I decided to try adjunct therapy with Seroquel to "boost" the effect of the Brintellix I take. I was really pleased to find it has a significant effect on my anxiety, which has always been a major component of my depression. While it didn't get rid of my depression, I feel better overall than I have in ages. Downsides? It's expensive if you don't have good insurance. I get a 90-day supply for $80. It also will knock you the heck out. I have to take mine before 6 p.m. or I will have great difficulty in waking up (even with an alarm). It has a heavy sedating effect."
garybooberry (taken for 1 to 6 months) May 10, 2016
41 users found this comment helpful.
"It was mainly prescribed as a sleep aid, in addition to its antidepressant qualities. I was on regular Seroquel and now on XL as I have trouble staying asleep. It's slightly better. I'm getting 6 hours of sleep a night. I am not usually groggy or snowed by this, maybe once per 30 doses. I'm ok with it. Only downside is cost (XL is brand)"
Anonymous (taken for 1 to 6 months) March 30, 2016
20 users found this comment helpful.
"I've been on Venlafaxine 300mg along with Quetiapine, Mirtazapine and Pregabalin for Major Depression for around 7 years.Augmentation therapy works for me. It's not perfect, but this level of Venlafaxine along with the other meds has kept me alive. I'm not getting better, but I'm certainly more stable and not going downhill and not suicidal. So in conclusion, don't be scared of meds, they may just save your life."
robbieMac (taken for 5 to 10 years) December 24, 2015
63 users found this comment helpful.
"My experience on Seroquel nearly cost me my job as it turned me into a ZOMBIE!. Since going off the drug I am fully functional. My head is clear and I have energy to do things. I cannot believe my Dr prescribed me an antipsychotic drug such as seroquel. Colleagues observing me thought I had undergone a major personality disorder. I have been off it for a month now and not missing it one bit."
Arri (taken for 1 to 6 months) November 11, 2015
41 users found this comment helpful.
"I was diagnosed with bipolar disorder 8 months ago (i am 19) but I do not have that. Instead I have BPD and depression. I was taking olanzapine which took away my entire life - I could barely do anything, but for the past 2 days with seroquel it has almost the opposite effect. Together with Prozac I have felt more motivated and less suicidal. Also I'm able to control my anxiety and I have more control over my behaviour. I also have trouble focusing but this has helped me focus on therapy a lot more. Sleep not great but I'm only on 25mg ; I only sleep for about 6-7 hours and then wake up and keep going back to sleep. This is the first drug that's given me hope."
Issy96 November 10, 2015
48 users found this comment helpful.
"I have taken it for PTSD at night for a long time. I'm able to sleep without having horrific nightmares. There is weight gain, but that boosts me to eat healthy and exercise, which helps my depression! klonipin to help with daytime anxiety and Seroquel before bed are the two drugs that keep me sane and able to live a normal life."
Kmtdstr (taken for 2 to 5 years) October 2, 2015
55 users found this comment helpful.
"Hate this med. Constantly sick on it. Stomach pain, severe diarrhea, passing out, severe dizziness and unable to wake up. Hungry for food all the time. Nasty taste in mouth. Thirsty all the time. Can't motivate myself to do anything. This was on the lowest dose available. Won't take it ever again don't care what my doctor says. No way."
sick constantly (taken for 1 to 6 months) August 26, 2015
33 users found this comment helpful.
"In the beginning I was on 300 mg of seroquel (not extended release) for 3 years. Got pregnant they took me off. I moved provinces they ended up putting me back on a smaller dose 150mg sleeping wise I would go to sleep right away and stay asleep all night. For the past 2 months they decided to put me on 150mg seroquel xl now it takes me hours to fall asleep and I wake up constantly throughout the night and have a hard time falling back asleep! I feel like xl does not work near as good depression wise and sleeping wise."
Amanda7106 July 23, 2015
19 users found this comment helpful.
"Seroquel XR worked very well for me with a combination of Seroquel and Zoloft together. I've been well for over 3 years now. Usually I would fall in to a depression with in a year just taking an antidepressent Because my body would build a tolerance to the medications. I know this medicine isn't for everyone, but I've had a very good experience and I'm stable and happy."
cdfig83 February 20, 2015
88 users found this comment helpful.
"I was prescribed seroquel 100mg for Post Traumatic Stress Disorder and I could only take it for two days. I took it as prescribed before bedtime. I almost crashed my truck several times on my way to work and I had to pull over on the shoulder to sleep on my way home from work. Day 2 was a Saturday. I slept for 14.5 hours. I can't function at all on this."
Mikfr November 28, 2014
64 users found this comment helpful.
"I have only been on Seroquel 25 mg for just over a week. So I cannot say if I will experience the weight gain or not. But so far this is the best thing that's worked for me. I was horrifically depressed and anxious for over a year, and before that moderately. But after just 1 days on the Seroquel I felt a huge difference. My thoughts had slowed down, my anxiety and depression got cut in half, my appreciation of time and continuity came back a bit, the disassociation was appeased. For the past year I felt like I was on one giant bad paranoia trip, and only after I started taking this medicine did I feeling normal again. There are still major things that are a problem, but the Seroquel makes it way more manageable."
sarrakii (taken for less than 1 month) June 14, 2014
156 users found this comment helpful.
"I am presently in hospital and have been put on Seroquel XR. As previously commented, the low dosages cause lethargy and sleepiness. However, I am not nearly as suicidal as I was, I have hope for the future and have not been on for more than a few days. I am optimistic that once I have reached the proper dosage that I will once again enjoy life as I once did. Paxil, Effexor and a number of other antidepressants worsened by symptoms over time and/or never did do much for the depressive symptoms in the first place. This medicine is worth trying if you are extremely depressed or suicidal."
WannaBeBetterForever February 7, 2014
111 users found this comment helpful.
"Made me a zombie at low doses and didn't help with depression. In fact, I felt even more depressed since I wasn't able to hold a conversation or think straight due to drowsiness.But it seems to work for some people."
Anonymous (taken for 1 to 6 months) January 5, 2014
78 users found this comment helpful.
"I have had Bipolar Disorder/Personality Disorder and severe depression for about 30 years and have tried just about every medicine there is. A recent set-back had me in hospital: my Dr. decided to put me on Seroquel XR 400 mg along with my other medicines. In the beginning it seemed to help me, as time went on my symptoms of low mood suicidal thoughts, etc. came back...most important to note was the WEIGHT GAIN. In under a year almost 50 lbs for no real reason. Extreme fatigue and sleepiness-hard to get out of bed in the mornings! Am now reducing dosage to slowly get off it as per Dr.'s orders and switching to an alternative. I am hoping this will work."
Koosh's Mom (taken for 6 months to 1 year) November 20, 2013
70 users found this comment helpful.
"I have used this for years now! I love it, before taking I absolutely could not sleep. I started out with 50mg, and am now taking 75mg after all of these years. I cannot sleep without it and I have no side effects from this medicine. "
shellwoo November 14, 2013
90 users found this comment helpful.
"I have been on 400mg of Seroquel XR along with my antidepressant for more than 1 year. Initially the medicine worked great for my Stress, Delusions and helped me sleep well in the night. Lately the anxiety has returned and I have severe anxiety during the day time. In the night I pass out so don't feel much in the night. However this medicine has caused me gain a lot of weight. I would say I have gained about 25 pounds since starting the medicine."
Indian Guy (taken for 1 to 2 years) September 25, 2013
50 users found this comment helpful.
"I have had depression since I was a child but I didn't start getting help for it until I was 19. I have tried Prozac and Celexa which did nothing for me and then my doctor asked me if I have ever heard of a medicine called Seroquel XR. I started out on 50mg and then worked my way up to 300mg. The only side effects for me were weight gain and drowsiness but the drowsiness went away after a couple of months of using this medicine. Overall I really like this medicine. It has helped me tremendously!"
Anonymous (taken for 6 months to 1 year) June 6, 2013
97 users found this comment helpful.
"After taking Seroquel for 5 months at 25 mg, I recently upped it to 50 mg at night-time. This has resulted in me being able to drop my Ativian from 2 mg to 1 mg and still get a great sleep. I am much more productive, think clearly and feel positive. I feel like my personality is coming back. Coincidence? I think not."
TOC Wildcat (taken for 1 to 6 months) May 30, 2013
115 users found this comment helpful.
"I was put on 25mg of Seroquel at age 15 due to major depression. I agree with the previous comment made, even on such a low dose I also feel I'm in a chemical straight jacket. I have trouble thinking straight, I can't concentrate for over 15 minutes, my sleep is average - it's extremely hard to wake up. I also find I'm so much more angrier and impulsive, I stutter and can't form words, as well as shaking uncontrollably in my legs when I get anxious. I also get headaches or even at least twice per week. However, my family and close friends have noticed a considerable improvement in my mental health eg suicidal thoughts have almost stopped completely and an increase in more 'happy Emma days'. Such a strong, powerful and dangerous med"
Emma (taken for 1 to 2 years) April 30, 2013
46 users found this comment helpful.
"I have been on a few antidepressants for 11 years with only fair results. My Doctor started me on some Seroquel XR 200mg at bedtime over the last few weeks. This medication not only has helped me with the terrible side effects when you come off many of the typical SSRI but I am sleeping and my depression has improved from a 2 out of 10 to 7 out of ten. Sometimes, SSRI medication side effects are stated as minor but they can be very severe at times. More Doctors should know about Seroquel XR and the great results when stopping antidepressants."
Midnight Cowboy (taken for less than 1 month) April 23, 2013
58 users found this comment helpful.
"Quetiapine 25mg used to get over Post traumatic stress disorder post Mental Health problems caused by an allergy to Valium. Presently taking 50% of a tablet at night."
angela offer December 16, 2012
31 users found this comment helpful.
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- Drug class: atypical antipsychotics